ID M0ZVT8_SOLTU Unreviewed; 439 AA.
AC M0ZVT8;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=3-dehydroquinate synthase {ECO:0000256|ARBA:ARBA00013031};
DE EC=4.2.3.4 {ECO:0000256|ARBA:ARBA00013031};
GN Name=102598775 {ECO:0000313|EnsemblPlants:PGSC0003DMT400009226};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400009226, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400009226}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400009226};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-
CC dehydroquinate + phosphate; Xref=Rhea:RHEA:21968, ChEBI:CHEBI:32364,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58394; EC=4.2.3.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001393};
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
CC -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis;
CC chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step
CC 2/7. {ECO:0000256|ARBA:ARBA00004661}.
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DR RefSeq; XP_006340763.1; XM_006340701.2.
DR AlphaFoldDB; M0ZVT8; -.
DR STRING; 4113.M0ZVT8; -.
DR PaxDb; 4113-PGSC0003DMT400009226; -.
DR EnsemblPlants; PGSC0003DMT400009226; PGSC0003DMT400009226; PGSC0003DMG400003582.
DR GeneID; 102598775; -.
DR Gramene; PGSC0003DMT400009226; PGSC0003DMT400009226; PGSC0003DMG400003582.
DR KEGG; sot:102598775; -.
DR eggNOG; KOG0692; Eukaryota.
DR HOGENOM; CLU_001201_0_2_1; -.
DR InParanoid; M0ZVT8; -.
DR OMA; TGINTPY; -.
DR OrthoDB; 865at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0003856; F:3-dehydroquinate synthase activity; IBA:GO_Central.
DR GO; GO:0008652; P:amino acid biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IBA:GO_Central.
DR CDD; cd08195; DHQS; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR HAMAP; MF_00110; DHQ_synthase; 1.
DR InterPro; IPR016037; DHQ_synth_AroB.
DR InterPro; IPR030960; DHQS/DOIS.
DR NCBIfam; TIGR01357; aroB; 1.
DR PANTHER; PTHR43622; 3-DEHYDROQUINATE SYNTHASE; 1.
DR PANTHER; PTHR43622:SF7; 3-DEHYDROQUINATE SYNTHASE, CHLOROPLASTIC; 1.
DR Pfam; PF01761; DHQ_synthase; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Aromatic amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023141};
KW Lyase {ECO:0000256|ARBA:ARBA00023239}; NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000011115}.
FT DOMAIN 143..401
FT /note="3-dehydroquinate synthase"
FT /evidence="ECO:0000259|Pfam:PF01761"
SQ SEQUENCE 439 AA; 47854 MW; 980C8ED471D4D6B8 CRC64;
MASSFCPKQA LSFTNSAHQS RAIPRDIHVR FPASVSSPSS RCGLKLKATT RLKVLATYAT
KVMDQSSSKA SSQAPTVVEV DLGNRSYPIY IGAGLLDQPD LLQRHIHGKR VLVVTNTTVA
PLYLDKTIST LTDGNPNVTV ESVILPDGEQ FKNMETLMKV FDKAIESRLD RRCTFVALGG
GVIGDMCGYA AASYLRGVNF IQIPTTVMAQ VDSSVGGKTG INHPLGKNMI GAFYQPQCVL
IDTDTLNTLP DRELASGLAE VIKYGLIRDA EFFEWQEQNM PLLLARDPTA FTYAIKRSCE
NKAEVVSQDE KESGVRATLN LGHTFGHAVE TGVGYGQWLH GEAVAAGTVM AVDMSRRLGW
IDDSLVQRVQ KILEQAKLPT SPPEIMTVEM FKSIMAVDKK VADGKLRLIL LNGSLGNCVF
TGDYDQKALD ETLRAFSKS
//
