ID M0ZWD8_SOLTU Unreviewed; 363 AA.
AC M0ZWD8;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Pre-pro-cysteine proteinase {ECO:0000313|EnsemblPlants:PGSC0003DMT400009507};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400009507, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400009507}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400009507};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR AlphaFoldDB; M0ZWD8; -.
DR SMR; M0ZWD8; -.
DR STRING; 4113.M0ZWD8; -.
DR MEROPS; C01.022; -.
DR PaxDb; 4113-PGSC0003DMT400009507; -.
DR EnsemblPlants; PGSC0003DMT400009507; PGSC0003DMT400009507; PGSC0003DMG400003707.
DR Gramene; PGSC0003DMT400009507; PGSC0003DMT400009507; PGSC0003DMG400003707.
DR Gramene; RHC04H1G3053.2.1; RHC04H1G3053.2.1; RHC04H1G3053.2.
DR eggNOG; KOG1542; Eukaryota.
DR HOGENOM; CLU_012184_1_3_1; -.
DR InParanoid; M0ZWD8; -.
DR OMA; KNDCDAG; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:GO_Central.
DR GO; GO:0051603; P:proteolysis involved in protein catabolic process; IBA:GO_Central.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF1027; PREPROCYSTEINE PROTEINASE-RELATED; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..363
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018716491"
FT DOMAIN 47..103
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 130..354
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 363 AA; 40120 MW; D9F127BA7A3B385D CRC64;
MDRLFLLSLL ALALFSSAIA FSDDDPLIRQ VVSENDDNHM LNAEHHFSLF KVKFGKIYAS
QEEHDHRLKV FKANLRRARR HQLLDPSAEH GITQFSDLTP SEFRRTYLGL NKPRPNLNAE
KAPILPTTDL PADFDWREKG AVTDVKNQGS CGSCWSFSTT GAVEGAHFLA TGELVSLSEQ
QLVDCDHECD PVEKNDCDAG CGGGLMTSAF EYTLKSGGLQ LEKDYPYTGK DGKCHFDKSK
IAASVSNFSV VGLDEDQIAA NLLKHGPLAV GINAAWMQTY VRGVSCPLIC LKRQDHGVLL
VGYGSEGFAP IRLKNKPYWI IKNSWGKTWG EHGYYKICRG HNICGVDAMV STVTATHTTN
PNL
//
