ID M0ZZN5_SOLTU Unreviewed; 92 AA.
AC M0ZZN5;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=NBS-coding resistance gene analog {ECO:0000313|EnsemblPlants:PGSC0003DMT400011507};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400011507, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400011507}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400011507};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- FUNCTION: Confers resistance to late blight (Phytophthora infestans)
CC races carrying the avirulence gene Avr1. Resistance proteins guard the
CC plant against pathogens that contain an appropriate avirulence protein
CC via an indirect interaction with this avirulence protein. That triggers
CC a defense system including the hypersensitive response, which restricts
CC the pathogen growth. {ECO:0000256|ARBA:ARBA00002074}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR AlphaFoldDB; M0ZZN5; -.
DR PaxDb; 4113-PGSC0003DMT400011507; -.
DR EnsemblPlants; PGSC0003DMT400011507; PGSC0003DMT400011507; PGSC0003DMG400004524.
DR Gramene; PGSC0003DMT400011507; PGSC0003DMT400011507; PGSC0003DMG400004524.
DR HOGENOM; CLU_2549963_0_0_1; -.
DR InParanoid; M0ZZN5; -.
DR OMA; YFPNDEN; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1235; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Hypersensitive response {ECO:0000256|ARBA:ARBA00022667};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Plant defense {ECO:0000256|ARBA:ARBA00022667};
KW Reference proteome {ECO:0000313|Proteomes:UP000011115}.
FT DOMAIN 2..71
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 92 AA; 10525 MW; 796DB4C92CD7B59B CRC64;
MDDNELADLV QKNLKDQRYL VVVDEIWSSD VWDSIRGIFP ICNNGSRILL TTRETEVAMY
AGAYTGEGHR VHVNPWSPPE IIYSSVIFLK NI
//
