ID M1A225_SOLTU Unreviewed; 1388 AA.
AC M1A225;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Disease resistance RPP13-like protein 1 {ECO:0008006|Google:ProtNLM};
GN Name=102584239 {ECO:0000313|EnsemblPlants:PGSC0003DMT400012949};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400012949, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400012949}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400012949};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR RefSeq; XP_015162418.1; XM_015306932.1.
DR PaxDb; 4113-PGSC0003DMT400012949; -.
DR EnsemblPlants; PGSC0003DMT400012949; PGSC0003DMT400012949; PGSC0003DMG400005046.
DR GeneID; 102584239; -.
DR Gramene; PGSC0003DMT400012949; PGSC0003DMT400012949; PGSC0003DMG400005046.
DR KEGG; sot:102584239; -.
DR eggNOG; KOG4658; Eukaryota.
DR HOGENOM; CLU_000837_8_8_1; -.
DR InParanoid; M1A225; -.
DR OMA; FESTISW; -.
DR OrthoDB; 657067at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 5.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1257; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000011115}.
FT DOMAIN 7..102
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 170..392
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 1388 AA; 157765 MW; AB4DC645C8FD58C7 CRC64;
MVWWEAVLSP ALQVLFDKLA SGDILNILKV WNVNELLLDK LKISYFINTA VLDDAEEKQY
LNPAVETWID MLRDAVFEAE DTLDELATEA LRCKLETDSQ KFSQQVRNSW NFISMKSRIE
ELITRLEYIA KQKDVLGLES NKKCCYGKMY RGTPSTPLLL GSHVYGRYTE KEELIELLVS
DCDDTNRVAP FCVIPLIGMG GIGKTTLAQI VYNDKRICEE FDVKAWAWVS DDFSVTSITK
SLLESATAKP FDTNSLEIIQ NGLKNMFSKK RILIVLDDVW SESCDDWNEL LIPFFEGDKR
SKIIVTTRNE GVASITGMLA PYRLQEMSHD DCWSLFLHHA FGVRGMDMNP RLKEIGEEIV
KRCKGLPLAI KTLGGMLSLK LDITYWTEVL NSNLWDLPSK KYSVLPSLRL SYHHLPPNLR
RCFAYCSIFP KGYEFNKKDL VLLWMAEGFV QPMAQITMEE VGNGNFTELQ SRCFFQESSQ
NRSLFVMHDL VHDLALSVSR RTCIQLEENW KCRFYENCEK ARYFSCIRSK YDVFRKFEML
SEMKRLRTFL PLASSEGAEF CYLTKKVLSD ILPKLSCLRV LSLSYYCVTE IPESIGFLKH
LRFLNFSYTE IKYLPQSISD LYNLQTLLLC NCYYLIELPA DMGKLLNLRY LDVSGSGLQK
ISLGLDKLVC LRTLPEFVVG SNVSSNRTLP EFTVDTNTGG TFDQKSKGSG IGALGNLLHL
EGSLSILNLE NVDNIWDAHG ASLITKKHLR ELLLQWSDSF EDPEKARMET DVLELLRPHQ
NIEKVTIKGY SGTKLPTWTA NPSFHKLVSL SLINCKGCRF LPSLGQLPSL KNLMVKGLSK
IKSIGDEFFG YTSTILTPFA SLETLSFTDM LEWEDWLLGY DGDRKAFCNL LELHLEECPK
LRGELPDVLP CLVKLVICEC KQLDSSLPRL PQLNELELRS CHVRLISSMH EVTKLTSLQL
SNLSNEYVPE CFLASLRHLV IRHCDLLVSL FEEGQNLPRR LEYVELENCH NLQKLPSLLH
TLTSLEVVII TNCPRLESFA RKIFPSNLKA LAIQGCSLES LPEAMMNSIS SLKYLSINGC
LMLASFPRGS ELLPTTCQQL KIEKCPNLEF LPEGMMHISN TSLQVLEIFD CSSISSFPGG
QLPDTLKTLT VWNCFNLEAL PDIRTSTMLL ESLRVGNCTS LKHLPHGLNK LLNLSYFEVD
GCHGIKCFPL EGLPQNLTKV LIIDCENLTF LPKWMQNLTS LQELQLSNCP LITSFTEGGF
PTSLVSLDVK DCKNLMPMSE WGLHRLASLR RLTIHGISSN LSYFPQWLLP STLETLNIVQ
LSNLESLSPW LQNLTSLENL KVKDCRKLLS LPKEDMPPML SYLEISECPL SEQKCDLSKI
DHIPCTVM
//
