ID M1ALR5_SOLTU Unreviewed; 708 AA.
AC M1ALR5;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=FtsH {ECO:0000313|EnsemblPlants:PGSC0003DMT400025632};
GN Name=102591510 {ECO:0000313|EnsemblPlants:PGSC0003DMT400025632};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400025632, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400025632}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400025632};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: In the C-terminal section; belongs to the peptidase M41
CC family. {ECO:0000256|ARBA:ARBA00010044}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the AAA ATPase
CC family. {ECO:0000256|ARBA:ARBA00010550}.
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DR RefSeq; XP_006342112.1; XM_006342050.2.
DR AlphaFoldDB; M1ALR5; -.
DR STRING; 4113.M1ALR5; -.
DR MEROPS; M41.020; -.
DR PaxDb; 4113-PGSC0003DMT400025632; -.
DR EnsemblPlants; PGSC0003DMT400025632; PGSC0003DMT400025632; PGSC0003DMG400009900.
DR GeneID; 102591510; -.
DR Gramene; PGSC0003DMT400025632; PGSC0003DMT400025632; PGSC0003DMG400009900.
DR KEGG; sot:102591510; -.
DR eggNOG; KOG0731; Eukaryota.
DR InParanoid; M1ALR5; -.
DR OMA; NIEMPDK; -.
DR OrthoDB; 9585at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR ExpressionAtlas; M1ALR5; baseline.
DR GO; GO:0009534; C:chloroplast thylakoid; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IBA:GO_Central.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IBA:GO_Central.
DR CDD; cd19501; RecA-like_FtsH; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.720.210; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.58.760; Peptidase M41; 1.
DR HAMAP; MF_01458; FtsH; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR005936; FtsH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000642; Peptidase_M41.
DR InterPro; IPR037219; Peptidase_M41-like.
DR NCBIfam; TIGR01241; FtsH_fam; 1.
DR PANTHER; PTHR23076:SF97; ATP-DEPENDENT ZINC METALLOPROTEASE FTSH 2, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR23076; METALLOPROTEASE M41 FTSH; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF01434; Peptidase_M41; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF140990; FtsH protease domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 195..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 286..425
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 708 AA; 75961 MW; 409F91D344703107 CRC64;
MANSVLSSNF LGSQIFVSPP TPKTSKYFHF HSKRKCIVPQ SILNKKPNSD NFKNVPSKAA
LAALLFSSIT PHAFALDNTT PAAPPQVIEA EALKPSASNS LPFAQNIILN APKTQAQPAS
DLPEGTQWRY SEFLNAVKKG KVERVRFSKD GSTLQLTAVD GRRANVIVPN DPDLIDILAM
NGVDISVSEG EGGNGLFSVI GNLLFPIIAF AGLFFLFRRS QGGPGGPGGL GGPMDFGRSK
SKFQEVPETG VTFADVAGAD QAKLELQEVV DFLKNPDKYT ALGAKIPKGC LLVGPPGTGK
TLLARAVAGE AGVPFFSCAA SEFVELFVGV GASRVRDLFE KAKSKAPCIV FIDEIDAVGR
QRGAGLGGGN DEREQTINQL LTEMDGFSGN SGVIVLAATN RPDVLDSALL RPGRFDRQVT
VDRPDVAGRV RILQVHSRGK ALAKDVDFDK IARRTPGFTG ADLQNLMNEA AILAARRDLK
EISKDEISDA LERIIAGPEK KNAVVSDEKK KLVAYHEAGH ALVGALMPEY DPVAKISIIP
RGQAGGLTFF APSEERLESG LYSRSYLENQ MAVALGGRVA EEVIFGQDNV TTGASNDFMQ
VSRVARQMVE RLGFSKKIGQ VAIGGGGGNP FLGQQMSTQK DYSMATADVV DAEVRELVEK
AYERATQIIT THIDILHKLA QLLIEKETVD GEEFMSLFID GKAELFIS
//
