ID M1ALZ9_SOLTU Unreviewed; 982 AA.
AC M1ALZ9;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN Name=102602562 {ECO:0000313|EnsemblPlants:PGSC0003DMT400025747};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400025747, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400025747}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400025747};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_006342066.1; XM_006342004.2.
DR AlphaFoldDB; M1ALZ9; -.
DR STRING; 4113.M1ALZ9; -.
DR PaxDb; 4113-PGSC0003DMT400025747; -.
DR EnsemblPlants; PGSC0003DMT400025747; PGSC0003DMT400025747; PGSC0003DMG400009941.
DR GeneID; 102602562; -.
DR Gramene; PGSC0003DMT400025747; PGSC0003DMT400025747; PGSC0003DMG400009941.
DR KEGG; sot:102602562; -.
DR eggNOG; ENOG502QQ4T; Eukaryota.
DR HOGENOM; CLU_000288_22_1_1; -.
DR InParanoid; M1ALZ9; -.
DR OMA; GQFMVFN; -.
DR OrthoDB; 1203965at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR ExpressionAtlas; M1ALZ9; baseline.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProt.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48056; LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED; 1.
DR PANTHER; PTHR48056:SF44; RECEPTOR PROTEIN KINASE CLAVATA1; 1.
DR Pfam; PF00560; LRR_1; 5.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00369; LRR_TYP; 7.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..982
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004011457"
FT TRANSMEM 640..663
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 693..969
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 982 AA; 108284 MW; 75196161FB1208CC CRC64;
MSLPKKISLF LQIFIFFVFS INANSDLETL LKLKESMVAP GTSALLDWNN NTNYPFSHCS
FSGVTCNNNS HVISINITNV PLFGTIPPEI GLLLNLENLI IFGDNITGTL PLEMSQLSSI
KHVNLSYNNF SGPFPREILL GLIKLESFDI YNNNFTGELP TEFVKLKKLE TLHLGGNYFH
GEIPEVYSHI VSLKWLGLEG NSLTGKIPKS LASLPNLEEL RLGYYNSYEG GIPSEFGNIS
TLKLLDLGNC NLDGEVPPSL GNLKKLHTLF LQVNRLTGRI PSELSGLESL MSFDLSFNQL
TGEIPESFVK LQNLTLINLF RNNLHGPIPP FIGDLPNLEV LQIWGNNFTL ELPENLGRNG
RFLFLDISIN HFTGRIPPDL CKGGKLKTLI LMENYFFGPI PEQLGECKSL ARIRVRKNYL
NGTIPAGFFK LPALDMLELD NNYFTGELPT EINANNLTKL VLSNNWITGN IPPSLGNLKN
LVTLSLDMNR LSGEIPQEIA SLNKLVTINL SGNNLTGEIP SSIALCSELT LVDLSRNQLV
GEVPKEITKL NSLNALNLSR NQLSGAIPGE VGVMNGLTVL DLSYNDLSGR RPTNGQLKFF
NDTYFVGNPK LCSPHATFCP SASNSPQNAL KIHSGKFTTI QLVITIIILV TVALLLAVTV
LFIKKEKFKN SKLWKLTAFQ KLDFRAEDVL ECLKEENIIG KGGAGVVYRG SMSNGIDVAI
KKLVGRGTGH HDHGFSAEIQ TLGRIRHRNI VRLLGYVSNK DTNLLLYEYM SNGSLGEMLH
GAKGAHLKWE TRYRIAVEAA KGLCYLHHDC SPSIIHRDVK SNNILLDSDY EAHVADFGLA
KFLQDAGASE CMSSIAGSYG YIAPEYAYTL KVDQKSDVYS FGVVLLELIT GHKPVGEFGD
GVDIVRWVNK TMSELSQPSD AASVLAVVDS RLHSYPLASV INLFKIAIMC VEEESCARPT
MREVVHMLTN LPQSTTTTLL AL
//
