ID M1B7H9_SOLTU Unreviewed; 334 AA.
AC M1B7H9;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Mitogen-activated protein kinase kinase kinase {ECO:0000313|EnsemblPlants:PGSC0003DMT400038860};
GN Name=102581172 {ECO:0000313|EnsemblPlants:PGSC0003DMT400038860};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400038860, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400038860}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400038860};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily.
CC {ECO:0000256|RuleBase:RU000304}.
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DR RefSeq; XP_006364160.1; XM_006364098.2.
DR AlphaFoldDB; M1B7H9; -.
DR STRING; 4113.M1B7H9; -.
DR PaxDb; 4113-PGSC0003DMT400038860; -.
DR EnsemblPlants; PGSC0003DMT400038860; PGSC0003DMT400038860; PGSC0003DMG400015018.
DR GeneID; 102581172; -.
DR Gramene; PGSC0003DMT400038860; PGSC0003DMT400038860; PGSC0003DMG400015018.
DR KEGG; sot:102581172; -.
DR eggNOG; KOG0198; Eukaryota.
DR HOGENOM; CLU_000288_63_23_1; -.
DR InParanoid; M1B7H9; -.
DR OMA; ETWITVR; -.
DR OrthoDB; 460351at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IBA:GO_Central.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR CDD; cd06606; STKc_MAPKKK; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48011; CCR4-NOT TRANSCRIPTIONAL COMPLEX SUBUNIT CAF120-RELATED; 1.
DR PANTHER; PTHR48011:SF35; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3-LIKE; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW Serine/threonine-protein kinase {ECO:0000256|RuleBase:RU000304};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 3..258
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 32
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 334 AA; 37304 MW; 4A6E2B6FEC82EA2C CRC64;
MDWTRGQTIG HGSTAAVSVA KSRFSDEVFA VKSVELSQSQ LLQKEQKILS QLSSSYVVSY
KGYDVTKEND KLMFNLMMEY MPDGTLSDEI RKQGGRINEP LIGYYTKQIL KGLEYLHSGG
IAHCDIKGQN ILLGKTGAKI ADFGCARWID PAERDGGAEP IGGTPMFMAP EVARGEEQGC
PADIWGLGCT IIEMVTGGSP WTNVTNAASL LYKIAFSGQS PEIPKFLSLQ ARDFLSKCLR
RDPKERWIAK QLLKHTFLEE FNLNSNSNQN FVTSSPTSIL DQDIWNSVEE SETTILQTGS
SPLQRVRELC SNSGELNWRW NDDERWITIR SSNR
//
