ID M1B9C1_SOLTU Unreviewed; 103 AA.
AC M1B9C1;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=Histone H4 {ECO:0000256|RuleBase:RU000528};
GN Name=102604694 {ECO:0000313|EnsemblPlants:PGSC0003DMT400040121};
GN Synonyms=H4 {ECO:0000313|EMBL:QCI62726.1};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400040121, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400040121}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400040121};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
RN [3] {ECO:0000313|EMBL:QCI62726.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=31308437; DOI=.1038/s41598-019-46681-z;
RA Vulavala V.K.R., Fogelman E., Faigenboim A., Shoseyov O., Ginzberg I.;
RT "The transcriptome of potato tuber phellogen reveals cellular functions of
RT cork cambium and genes involved in periderm formation and maturation.";
RL Sci. Rep. 9:10216-10216(2019).
CC -!- FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact
CC DNA into chromatin, limiting DNA accessibility to the cellular
CC machineries which require DNA as a template. Histones thereby play a
CC central role in transcription regulation, DNA repair, DNA replication
CC and chromosomal stability. DNA accessibility is regulated via a complex
CC set of post-translational modifications of histones, also called
CC histone code, and nucleosome remodeling.
CC {ECO:0000256|RuleBase:RU000528}.
CC -!- SUBUNIT: The nucleosome is a histone octamer containing two molecules
CC each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and
CC two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of
CC DNA. {ECO:0000256|RuleBase:RU000528}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the histone H4 family.
CC {ECO:0000256|ARBA:ARBA00006564, ECO:0000256|RuleBase:RU000528}.
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DR EMBL; MH669359; QCI62726.1; -; mRNA.
DR RefSeq; XP_006340089.1; XM_006340027.2.
DR RefSeq; XP_006363342.1; XM_006363280.2.
DR RefSeq; XP_006365711.1; XM_006365649.2.
DR RefSeq; XP_015158892.1; XM_015303406.1.
DR AlphaFoldDB; M1B9C1; -.
DR SMR; M1B9C1; -.
DR STRING; 4113.M1B9C1; -.
DR PaxDb; 4113-PGSC0003DMT400007674; -.
DR EnsemblPlants; PGSC0003DMT400007674; PGSC0003DMT400007674; PGSC0003DMG400002965.
DR EnsemblPlants; PGSC0003DMT400022438; PGSC0003DMT400022438; PGSC0003DMG400008696.
DR EnsemblPlants; PGSC0003DMT400040121; PGSC0003DMT400040121; PGSC0003DMG400015525.
DR EnsemblPlants; PGSC0003DMT400040122; PGSC0003DMT400040122; PGSC0003DMG400015525.
DR EnsemblPlants; PGSC0003DMT400040182; PGSC0003DMT400040182; PGSC0003DMG400015545.
DR EnsemblPlants; PGSC0003DMT400060471; PGSC0003DMT400060471; PGSC0003DMG400023522.
DR EnsemblPlants; PGSC0003DMT400060472; PGSC0003DMT400060472; PGSC0003DMG400023523.
DR EnsemblPlants; PGSC0003DMT400071314; PGSC0003DMT400071314; PGSC0003DMG400027736.
DR EnsemblPlants; PGSC0003DMT400078154; PGSC0003DMT400078154; PGSC0003DMG400030399.
DR EnsemblPlants; PGSC0003DMT400078155; PGSC0003DMT400078155; PGSC0003DMG400030400.
DR EnsemblPlants; PGSC0003DMT400078156; PGSC0003DMT400078156; PGSC0003DMG400030401.
DR EnsemblPlants; PGSC0003DMT400097008; PGSC0003DMT400097008; PGSC0003DMG400046579.
DR GeneID; 102590298; -.
DR GeneID; 102604694; -.
DR GeneID; 102604795; -.
DR GeneID; 102605372; -.
DR Gramene; PGSC0003DMT400007674; PGSC0003DMT400007674; PGSC0003DMG400002965.
DR Gramene; PGSC0003DMT400022438; PGSC0003DMT400022438; PGSC0003DMG400008696.
DR Gramene; PGSC0003DMT400040121; PGSC0003DMT400040121; PGSC0003DMG400015525.
DR Gramene; PGSC0003DMT400040122; PGSC0003DMT400040122; PGSC0003DMG400015525.
DR Gramene; PGSC0003DMT400040182; PGSC0003DMT400040182; PGSC0003DMG400015545.
DR Gramene; PGSC0003DMT400060471; PGSC0003DMT400060471; PGSC0003DMG400023522.
DR Gramene; PGSC0003DMT400060472; PGSC0003DMT400060472; PGSC0003DMG400023523.
DR Gramene; PGSC0003DMT400071314; PGSC0003DMT400071314; PGSC0003DMG400027736.
DR Gramene; PGSC0003DMT400078154; PGSC0003DMT400078154; PGSC0003DMG400030399.
DR Gramene; PGSC0003DMT400078155; PGSC0003DMT400078155; PGSC0003DMG400030400.
DR Gramene; PGSC0003DMT400078156; PGSC0003DMT400078156; PGSC0003DMG400030401.
DR Gramene; PGSC0003DMT400097008; PGSC0003DMT400097008; PGSC0003DMG400046579.
DR Gramene; RHC04H1G0662.2.1; RHC04H1G0662.2.1.cds.1; RHC04H1G0662.2.
DR Gramene; RHC04H1G1134.2.1; RHC04H1G1134.2.1.cds.1; RHC04H1G1134.2.
DR Gramene; RHC06H1G0518.2.1; RHC06H1G0518.2.1.cds.1; RHC06H1G0518.2.
DR Gramene; RHC06H1G2945.2.1; RHC06H1G2945.2.1.cds.1; RHC06H1G2945.2.
DR Gramene; RHC06H1G2948.2.1; RHC06H1G2948.2.1.cds.1; RHC06H1G2948.2.
DR Gramene; RHC06H1G2963.2.1; RHC06H1G2963.2.1.cds.1; RHC06H1G2963.2.
DR Gramene; RHC11H1G2440.2.1; RHC11H1G2440.2.1.cds.1; RHC11H1G2440.2.
DR Gramene; RHC11H1G2442.2.1; RHC11H1G2442.2.1.cds.1; RHC11H1G2442.2.
DR Gramene; RHC11H1G2444.2.1; RHC11H1G2444.2.1.cds.1; RHC11H1G2444.2.
DR Gramene; RHC11H1G2446.2.1; RHC11H1G2446.2.1.cds.1; RHC11H1G2446.2.
DR KEGG; sot:102590298; -.
DR KEGG; sot:102604694; -.
DR KEGG; sot:102604795; -.
DR KEGG; sot:102605372; -.
DR eggNOG; KOG3467; Eukaryota.
DR HOGENOM; CLU_109117_2_3_1; -.
DR InParanoid; M1B9C1; -.
DR OMA; QKEHING; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR GO; GO:0006334; P:nucleosome assembly; IBA:GO_Central.
DR CDD; cd00076; H4; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR035425; CENP-T/H4_C.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR001951; Histone_H4.
DR InterPro; IPR019809; Histone_H4_CS.
DR PANTHER; PTHR10484; HISTONE H4; 1.
DR PANTHER; PTHR10484:SF0; HISTONE H4; 1.
DR Pfam; PF15511; CENP-T_C; 1.
DR PRINTS; PR00623; HISTONEH4.
DR SMART; SM00417; H4; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR PROSITE; PS00047; HISTONE_H4; 1.
PE 2: Evidence at transcript level;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454, ECO:0000256|RuleBase:RU000528};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU000528};
KW Nucleosome core {ECO:0000256|ARBA:ARBA00023269,
KW ECO:0000256|RuleBase:RU000528};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU000528};
KW Reference proteome {ECO:0000313|Proteomes:UP000011115}.
FT DOMAIN 39..96
FT /note="CENP-T/Histone H4 histone fold"
FT /evidence="ECO:0000259|Pfam:PF15511"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 103 AA; 11425 MW; A9E4B0EC3A2A7598 CRC64;
MSGRGKGGKG LGKGGAKRHR KVLRDNIQGI TKPAIRRLAR RGGVKRISGL IYEETRGVLK
IFLENVIRDS VTYTEHARRK TVTAMDVVYA LKRQGRTLYG FGG
//
