ID M1BBS0_SOLTU Unreviewed; 878 AA.
AC M1BBS0;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=NOL1/NOP2/sun family protein {ECO:0000313|EnsemblPlants:PGSC0003DMT400041672};
GN Name=102590670 {ECO:0000313|EnsemblPlants:PGSC0003DMT400041672};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400041672, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400041672}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400041672};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RsmB/NOP family. {ECO:0000256|ARBA:ARBA00007494,
CC ECO:0000256|PROSITE-ProRule:PRU01023}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01023}.
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DR RefSeq; XP_006353214.1; XM_006353152.2.
DR AlphaFoldDB; M1BBS0; -.
DR STRING; 4113.M1BBS0; -.
DR PaxDb; 4113-PGSC0003DMT400041672; -.
DR EnsemblPlants; PGSC0003DMT400041672; PGSC0003DMT400041672; PGSC0003DMG400016157.
DR GeneID; 102590670; -.
DR Gramene; PGSC0003DMT400041672; PGSC0003DMT400041672; PGSC0003DMG400016157.
DR Gramene; RHC11H1G0366.2.1; RHC11H1G0366.2.1; RHC11H1G0366.2.
DR KEGG; sot:102590670; -.
DR eggNOG; KOG2198; Eukaryota.
DR HOGENOM; CLU_005316_4_3_1; -.
DR InParanoid; M1BBS0; -.
DR OMA; QLFTEYV; -.
DR OrthoDB; 197651at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR ExpressionAtlas; M1BBS0; baseline.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IBA:GO_Central.
DR GO; GO:0016428; F:tRNA (cytidine-5-)-methyltransferase activity; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001510; P:RNA methylation; IBA:GO_Central.
DR GO; GO:0030488; P:tRNA methylation; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR018314; Fmu/NOL1/Nop2p_CS.
DR InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR InterPro; IPR023267; RCMT.
DR InterPro; IPR023270; RCMT_NCL1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR22808; NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR22808:SF1; RNA CYTOSINE C(5)-METHYLTRANSFERASE NSUN2; 1.
DR Pfam; PF01189; Methyltr_RsmB-F; 1.
DR PRINTS; PR02008; RCMTFAMILY.
DR PRINTS; PR02011; RCMTNCL1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS01153; NOL1_NOP2_SUN; 1.
DR PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01023}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU01023};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01023};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01023}; tRNA processing {ECO:0000256|ARBA:ARBA00022694};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555}.
FT DOMAIN 78..494
FT /note="SAM-dependent MTase RsmB/NOP-type"
FT /evidence="ECO:0000259|PROSITE:PS51686"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 505..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 563..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..50
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..524
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..633
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 346
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 196..202
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 228
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 293
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ SEQUENCE 878 AA; 98409 MW; 214B91E3A402679D CRC64;
MGGRGRSRTQ RKHFRQSREN VWKRSKHDDS GEKQDSVTTT NDGNKEHRHW EPFATQNLAF
DEYYKEQGIV PTEEWDTFIG FLRTPLPAAF RINSSAQCYV DIRTKLENDF MKSLQAEGVD
GSEIEGIKPL PWYPENLAWQ SNFSRNQLRK NQILERFHEF LKLQNEIGNI TRQEAVSMVP
PLFLDVRPDH FALDMCAAPG SKTFQLLEMI HHLAEPGTLP SGMVLANDVD VQRCNLLIHQ
TKRMSTANLI VTNHEAQHFP SCRLDRNFAN GSETQTVREL DINQLQFDRV LCDVPCSGDG
TLRKAPDIWR KWNAGNGNGL HGLQIQIAMR GLSLLKVGGR MVYSTCSMNP IENEAVVAEI
LRRCGESVEL VDVSSEVPQL VRRPGLKKWK VRDKGAWWTS YKDVPEGRRN AIVPGMFPSG
KTYLDASEKN DDATRDQLSD NGNNANVIEV LEDPATAATI SDEEVSTLPL ERCMRIVPHD
QNSGAFFVSV FQKLSPLPAA AFQQKKPVSS RGKPNSSDVI QAESLTTKVK EDVNVEDVKP
VDSVGTQEVT MDDADIQAES VTTKVKEDEN TEDVKPVNSV GSEDVTMDEA GNGTDETALD
TEPSEILEKT EKEETQPSTD TRAEPETVRG KRKLQMQGKW RGVDPVIFYK EEAVVSKIKD
FYGIKESFLF EGHLITRNSD MNHVKRIYHV SKSVKEVLHL NFLAGQQLKI ASVGLKMFER
QTSKDGASAS CIFRISSEGL PLMLPHITKQ ILYSSPADFK HLLQYKSIKL GDFVDAEFGE
KASQLLMGCC VVVLNKENKT LSEAQADPST IAIGCWRGRS NISVMVTALD CQELLERMSM
GVEEETKASS PEIMPSTNKA DEIVEAVEDE VKENTEQP
//
