ID M1BLL7_SOLTU Unreviewed; 514 AA.
AC M1BLL7;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Protein DETOXIFICATION {ECO:0000256|RuleBase:RU004914};
DE AltName: Full=Multidrug and toxic compound extrusion protein {ECO:0000256|RuleBase:RU004914};
GN Name=102583997 {ECO:0000313|EnsemblPlants:PGSC0003DMT400047906};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400047906, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400047906}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400047906};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC 2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199,
CC ECO:0000256|RuleBase:RU004914}.
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DR RefSeq; XP_006357608.1; XM_006357546.2.
DR AlphaFoldDB; M1BLL7; -.
DR PaxDb; 4113-PGSC0003DMT400047906; -.
DR EnsemblPlants; PGSC0003DMT400047906; PGSC0003DMT400047906; PGSC0003DMG400018618.
DR GeneID; 102583997; -.
DR Gramene; PGSC0003DMT400047906; PGSC0003DMT400047906; PGSC0003DMG400018618.
DR KEGG; sot:102583997; -.
DR eggNOG; KOG1347; Eukaryota.
DR HOGENOM; CLU_012893_1_4_1; -.
DR InParanoid; M1BLL7; -.
DR OMA; ARSHFKE; -.
DR OrthoDB; 10858at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IBA:GO_Central.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR CDD; cd13132; MATE_eukaryotic; 1.
DR InterPro; IPR045069; MATE_euk.
DR InterPro; IPR002528; MATE_fam.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR11206; MULTIDRUG RESISTANCE PROTEIN; 1.
DR PANTHER; PTHR11206:SF275; PROTEIN DETOXIFICATION 29-RELATED; 1.
DR Pfam; PF01554; MatE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU004914};
KW Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW Transmembrane {ECO:0000256|RuleBase:RU004914};
KW Transmembrane helix {ECO:0000256|RuleBase:RU004914}.
FT TRANSMEM 65..86
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 106..127
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 148..172
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 184..201
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 213..232
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 284..310
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 322..344
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 364..386
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 406..428
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 435..459
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 465..486
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
SQ SEQUENCE 514 AA; 56509 MW; B1BC5457687D0C97 CRC64;
MEDHNSKQNE PLLSQTEIST SDLDNNNSLI RSSFGSSFVA DADDIPPITG IQDFFREFTV
ESKKLWYLAG PAIFTSICQY SLGAVTQTFA GHLGTLELAA VSVENSVIAG FSFGVMLGMG
SALETLCGQA FGAGQIDMLG VYMQRSWVIL NSTAVILMFL YIFAAQFLRL IGQTEDISRE
AGKMALYMIP QLFAYAMNFP IAKFLQSQSK IMVMAWIAAI ALVFHTFFSW LLMLKLGWGL
VGAAVVLNSS WWFIVVAQML YIFSGTCGQA WSGFSWKAFV NLWGFVRLSL ASAVMLCLET
WYFMALVLFA GYLKNAEVAV DALSICMNIL GWAVMAAIGC NAAISVRVSN ELGAAHPRTA
KFSVVVVVFS SFLIGLLLSV FLLVFRSQYP SLFAESESVK RLVYELTPLL VFCMVVNNIQ
PALSGVAIGA GWQALVAYVN IACYYLFGIP LGLILGYKFN MGVQGIWYGM VSGTVIQTFV
LFWIVYKTNW NKEASIAAAR IKMWGGEPAN EIEK
//
