ID M1BUS8_SOLTU Unreviewed; 429 AA.
AC M1BUS8;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=ethanolamine-phosphate cytidylyltransferase {ECO:0000256|ARBA:ARBA00024221};
DE EC=2.7.7.14 {ECO:0000256|ARBA:ARBA00024221};
DE AltName: Full=CTP:phosphoethanolamine cytidylyltransferase {ECO:0000256|ARBA:ARBA00031473};
GN Name=102594626 {ECO:0000313|EnsemblPlants:PGSC0003DMT400053308};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400053308, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400053308}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400053308};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3.
CC {ECO:0000256|ARBA:ARBA00024191}.
CC -!- SIMILARITY: Belongs to the cytidylyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010101}.
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DR RefSeq; XP_006361583.1; XM_006361521.2.
DR RefSeq; XP_006361584.1; XM_006361522.2.
DR AlphaFoldDB; M1BUS8; -.
DR STRING; 4113.M1BUS8; -.
DR PaxDb; 4113-PGSC0003DMT400053308; -.
DR EnsemblPlants; PGSC0003DMT400053307; PGSC0003DMT400053307; PGSC0003DMG400020688.
DR EnsemblPlants; PGSC0003DMT400053308; PGSC0003DMT400053308; PGSC0003DMG400020688.
DR GeneID; 102594626; -.
DR Gramene; PGSC0003DMT400053307; PGSC0003DMT400053307; PGSC0003DMG400020688.
DR Gramene; PGSC0003DMT400053308; PGSC0003DMT400053308; PGSC0003DMG400020688.
DR KEGG; sot:102594626; -.
DR eggNOG; KOG2803; Eukaryota.
DR HOGENOM; CLU_031246_2_1_1; -.
DR InParanoid; M1BUS8; -.
DR OMA; CGVHNDE; -.
DR OrthoDB; 5474784at2759; -.
DR UniPathway; UPA00558; UER00742.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR ExpressionAtlas; M1BUS8; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004306; F:ethanolamine-phosphate cytidylyltransferase activity; IBA:GO_Central.
DR GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IBA:GO_Central.
DR CDD; cd02174; CCT; 1.
DR CDD; cd02173; ECT; 1.
DR Gene3D; 3.40.50.620; HUPs; 2.
DR InterPro; IPR041723; CCT.
DR InterPro; IPR004821; Cyt_trans-like.
DR InterPro; IPR044608; Ect1/PCYT2.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00125; cyt_tran_rel; 2.
DR PANTHER; PTHR45780; ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR45780:SF5; ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE; 1.
DR Pfam; PF01467; CTP_transf_like; 2.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 2.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000011115}.
FT DOMAIN 68..197
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
FT DOMAIN 266..362
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
SQ SEQUENCE 429 AA; 47709 MW; 555DD50DD1CE6BD9 CRC64;
MDFESNNWVW EGMYYYPRLF GGIMLTAALL GLSTSYFGGI SVPTLLYPFP YLSIFYKKKH
EKKRVRVYMD GCFDLMHYGH ANALRQAKAL GDELVVGVVS DEEIIATKGP PVLCMEERLA
LVSGLKWVDE VISSAPYAIT EDFMNRLFNE YKIDYIIHGD DPCLLPDGTD AYALAKKAGR
YKQIKRTEGV SSTDIVGRIL SASKSGDSPQ DCSNSTPVGE ADDIKNKFGA EKQAKGGQIS
HFLPTSRRIV QFSNGKGPAP NSRVVYIDGA FDLFHAGHVE ILRSARQHGD FLLVGIYPDQ
TVSELRGHQY PLMNLYERSL GVLACRYVDE VIIGAPWEVT QDMITTFNIS LVVHGTVSES
NSSTEGGQDP YAVPKSMGIF QVIESPKDIT TSSVAQRIIA NHEIYVKRNT KKAASEKKYY
AERKYVSGD
//
