ID M1C001_SOLTU Unreviewed; 1116 AA.
AC M1C001;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Serine/threonine protein kinase {ECO:0000313|EnsemblPlants:PGSC0003DMT400056866};
GN Name=102604714 {ECO:0000313|EnsemblPlants:PGSC0003DMT400056866};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400056866, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400056866}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400056866};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
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DR RefSeq; XP_006346025.1; XM_006345963.2.
DR RefSeq; XP_015163615.1; XM_015308129.1.
DR AlphaFoldDB; M1C001; -.
DR STRING; 4113.M1C001; -.
DR PaxDb; 4113-PGSC0003DMT400056866; -.
DR EnsemblPlants; PGSC0003DMT400056866; PGSC0003DMT400056866; PGSC0003DMG401022117.
DR GeneID; 102604714; -.
DR Gramene; PGSC0003DMT400056866; PGSC0003DMT400056866; PGSC0003DMG401022117.
DR KEGG; sot:102604714; -.
DR eggNOG; KOG0192; Eukaryota.
DR HOGENOM; CLU_003108_0_0_1; -.
DR InParanoid; M1C001; -.
DR OMA; EEWNELE; -.
DR OrthoDB; 47962at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IBA:GO_Central.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR CDD; cd06410; PB1_UP2; 1.
DR CDD; cd13999; STKc_MAP3K-like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR23257:SF957; KINASE SUPERFAMILY WITH OCTICOSAPEPTIDE_PHOX_BEM1P DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23257; SERINE-THREONINE PROTEIN KINASE; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR00109; TYRKINASE.
DR SMART; SM00666; PB1; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 835..1101
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 24..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 581..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 733..766
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 581..618
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 733..751
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 866
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1116 AA; 123477 MW; F89293BA65041C7C CRC64;
MEQSNHQNCS HFASAQQSNA EFQPDPQVLT MDPPDHTHHN LKAPNDNCSE AKPVLNFSLQ
TGEEFVLEFM RDRVNPGKNY VPSTSGDPSF PQGHLELKGI VGISHTVCED GSDTSMLAMV
EKGPKEFEKH DSSLHDDKNY NGSVVSVQQV SSDYNSFGSL MCTSSGICDD SVAKLKAMCS
FGGKILPRPS DGKLRYVGGE TRVIRIRKDI TWKVLWHKAV AIYDPTHIVK YQLPGEDFDA
LVTVSCDEDL QNMLEECNVL EDGDISKKLR IFLFSISDLD DAHSSLTNSD ADSEFQYVVA
INGLEMGSRN SSTLHYLGSS SNNLAELDGN NIEDSSRSVM GFIGASNLPS AGFDDSSLIT
KSANPNVPIP SSAYDIDLRI HYGQKENCDN SKQQQFQFGF NSNSHFINNI EGQGSQTQAK
QYGPAMYNKA FVPESVTLAV DSTDLSFSDP VPPTQRGFCS MQIPRGQVEL LSRLSKSDDS
HNSQFLATHS RADFSQQEIL KESIDKMQNR NMNEQLVSTE KSLCCAPQTA AHDLGVPLNL
KQVIPNAANM KNVVHVDQVP VANHQTVCTD NKYTNFLVKR TEDRGSRPNP LPHVDAENHH
EDGGDIHLKI HQGDRDGSNS NEKSQPSDWT GNYRECVLQG EPSVVLPRSE QGDILIDIND
RFPRDILSDI FAKAILSNSS SDISPVQQDG AGMSLNMQNE EPKHWSFFQK LAGDEFVRKD
ISLIDQDHIT FSPNLQKVDE EPPSTINLDP QRDSGGDGPK ELPHALGDVD SQLQLGFGAT
QTEVSEGIHD DVMMDKSKVL DIDSEDGFKN VGLPLGRTLA EIDINSLQII KNEDLEELKE
LGSGTFGTVY HGKWRGTDVA IKRIKKSCFT GQLSELERLA IEFWREAEIL SKLHHPNVVA
FYGVVQDGPG GTLATVAEYM ADGSLRHVLI RKDRHLDRRK RLIIAMDAAF GMEYLHSKNI
VHFDLKCDNL LVNLKDPSRP ICKVGDFGLS KIKRNTLVSG GVRGTLPWMA PELLNGSSSK
VSEKVDVFSF GIVLWEILTG EEPYANMHYG AIIGGIVNNT LRPTIPNYCD SEWRCLMEQC
WSPNPASRPS FTEIASRLRL LSSASQNKTT GQKATK
//
