ID M1C706_SOLTU Unreviewed; 736 AA.
AC M1C706;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Importin beta-2 subunit family protein {ECO:0000313|EnsemblPlants:PGSC0003DMT400061079};
GN Name=102606314 {ECO:0000313|EnsemblPlants:PGSC0003DMT400061079};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400061079, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400061079}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400061079};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR AlphaFoldDB; M1C706; -.
DR EnsemblPlants; PGSC0003DMT400061079; PGSC0003DMT400061079; PGSC0003DMG400023766.
DR Gramene; PGSC0003DMT400061079; PGSC0003DMT400061079; PGSC0003DMG400023766.
DR HOGENOM; CLU_003794_1_0_1; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR ExpressionAtlas; M1C706; baseline.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF6; IMPORTIN-4; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF03810; IBN_N; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 2.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011115}.
FT DOMAIN 23..89
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REPEAT 379..417
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 420..455
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 736 AA; 81318 MW; 10478CD8849AEF62 CRC64;
MAQSLELLLI QFLMPDNDAR RQAEDQIKRL AKDPQVVPSL IHHLRTAKTP NVRQLAAVLL
RKKITGHWAK LSPQHRQLVK QSLIESITME HSPPVRRASA NVISIVAKYA VPAGEWSDLL
PYLFQCSQSA QEDHREVALI LFSSLTETIG NSFQPYFADL QSLLLKCLQD ETSNRVRVAA
LKAVGSFLEF THDEAEVIKF REFIPSILNV SRQCLASGDE DVAVLAFEIF DELIESPAPL
LGDSVKAIVQ FSLEVCSSPT LESNTRHQAI QIISWLAKYK ANSLKKYKLV TPILQVMCPL
LAESTDRNED DDLAPDRAAA EVIDTMALNL SKHVFPPVLE FASLSSQSPN GKFREASVTS
LGVISEGCLE LMKNKLEPIL HIVLGSLRDP EQMVRGAASF ALGQFAEYLQ PEIVSHYESV
LPCILNAVED VSDEVKEKSY YALAAFCENM GEEILPFLDP LMGKLLGALQ SSPRNLQETC
MSAIGSVASA AEQAFVPYAE RVLELMKVFM VLTNDEDLLS RARATELVGI VAMSVGRTRM
EPVLPPFIEA AISGFGLEFS ELREYTHGFF SNIAEILDEG FAQYLPHVVP LAFNSCNLDD
GSAVDIDDSE EDENVHGFGG VSSDDEAHDE PRVRNISIRT GVLDEKAAAT QALGLFALHT
KGSYAPYLEE SFKILVRHSS YFHEDVRMQA IISLKYILIA TQAALQGHNV SNDLSPSIIV
VFSLSFIILH AVDTFC
//
