ID   M1C7H3_SOLTU            Unreviewed;       991 AA.
AC   M1C7H3;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 47.
DE   RecName: Full=DUF4378 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   Name=102591321 {ECO:0000313|EnsemblPlants:PGSC0003DMT400061432};
OS   Solanum tuberosum (Potato).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX   NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400061432, ECO:0000313|Proteomes:UP000011115};
RN   [1] {ECO:0000313|Proteomes:UP000011115}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX   PubMed=21743474; DOI=10.1038/nature10158;
RG   The Potato Genome Sequencing Consortium;
RT   "Genome sequence and analysis of the tuber crop potato.";
RL   Nature 475:189-195(2011).
RN   [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400061432}
RP   IDENTIFICATION.
RC   STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400061432};
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   RefSeq; XP_006345668.1; XM_006345606.2.
DR   AlphaFoldDB; M1C7H3; -.
DR   PaxDb; 4113-PGSC0003DMT400061432; -.
DR   EnsemblPlants; PGSC0003DMT400061432; PGSC0003DMT400061432; PGSC0003DMG400023907.
DR   GeneID; 102591321; -.
DR   Gramene; PGSC0003DMT400061432; PGSC0003DMT400061432; PGSC0003DMG400023907.
DR   KEGG; sot:102591321; -.
DR   eggNOG; ENOG502QSHY; Eukaryota.
DR   InParanoid; M1C7H3; -.
DR   OMA; SEHACNS; -.
DR   OrthoDB; 447818at2759; -.
DR   Proteomes; UP000011115; Unassembled WGS sequence.
DR   ExpressionAtlas; M1C7H3; baseline.
DR   InterPro; IPR022212; DUF3741.
DR   InterPro; IPR025486; DUF4378.
DR   PANTHER; PTHR46836; AFADIN; 1.
DR   PANTHER; PTHR46836:SF8; AFADIN; 1.
DR   Pfam; PF12552; DUF3741; 1.
DR   Pfam; PF14309; DUF4378; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000011115}.
FT   DOMAIN          180..224
FT                   /note="DUF3741"
FT                   /evidence="ECO:0000259|Pfam:PF12552"
FT   DOMAIN          838..986
FT                   /note="DUF4378"
FT                   /evidence="ECO:0000259|Pfam:PF14309"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          94..142
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          289..309
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          332..379
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          412..463
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          728..776
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        108..142
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        290..306
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        337..366
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        418..455
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   991 AA;  111208 MW;  C25233388B4E55EA CRC64;
     MEKSRHRKSR SASGIMEGSK LGKKQVATPK VTLNSRSYCD ETTRGDMIMH DLGKISSKRV
     TGTPIKNLLA EEMAKEGESK KRPTSIVARL MGLEGMPSPQ HIGRQQRRFS DSCQHRNEQI
     DSRRRKQLFD EQSSKRSSME HQEFKDVYED LEASHVGNRR HSSRWNETGR FATPDMALIQ
     QKFMDAKRLS TDERFQNSKE FNDTLEALDS NKELLLKYLQ EPDSLFVKHL QDLQVESASS
     TCSRIAVLKP SNSVKYEGSA KSSKSVRGGS CKQSISLQKE RLDGLLLQSQ HRHSGHNSQK
     SSPVLSEGKE ENILPTRIVV LKPNLGITQS NIASVPHHPD VRKHAQYHRA SPGGAGEEEE
     KNSSKNMGIS RPKSNEARDI AKEITRRMRD SFGPFDGRDA YFRGSGVKGY AGDESSCDVY
     ESDSTGDSDI TTLSCRKSSG RGNLKKSSSL GSESSVGREA KKRLSERWKM TQYYQDIEMA
     GKSSTLGEML SLPDGRMKHD YCDTMVHVEE ATNEPGGRKG TTEWDFPLGI SSRDGWKDVC
     INDSSGYRST SPPFCSKKHR TRARREVFSN KQCSISKEPV NREQSVNHHR SRSLDGMVNF
     RDEFLSKDSR SSKKKLHSYR LGSDSLSKGK LCQRIDMNLK EDLSEKRSLA SQVASADGLS
     YTNASDDAET ESITLSSEYS VEMHRKLPVE CGSASPINQE VSILQEALPE PSPPSSAAAS
     VVLEYPAPEP ESSVSSKEAD HRSPLSVLEY PAPEPESSVS SKEADHPSPP SVLEVPFTED
     VSSGSECFER VSAELNGLRM QLKLLKMESE PYADVILSDD EVEYFEDNCS LRSQSWQSSY
     IMDVLTDSGL KASDPDTFVT SFHTLECPLS PWIFDNLEKK YTDETTGPRY ERRLLFNRIN
     LGLLDIVRKY VDPCPWVKPI EGIDWKWETY GMKNILHQLL RSHEDPANAD TPGNVVEEMQ
     WLALKDDMDV TVKDIEELLI EDLIEEVVGA I
//