ID M1CDE5_SOLTU Unreviewed; 517 AA.
AC M1CDE5;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=UDP-MurNAc-pentapeptide synthetase {ECO:0000256|ARBA:ARBA00031461};
GN Name=102596832 {ECO:0000313|EnsemblPlants:PGSC0003DMT400065101};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400065101, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400065101}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400065101};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
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DR RefSeq; XP_006360840.1; XM_006360778.2.
DR AlphaFoldDB; M1CDE5; -.
DR STRING; 4113.M1CDE5; -.
DR PaxDb; 4113-PGSC0003DMT400065101; -.
DR EnsemblPlants; PGSC0003DMT400065101; PGSC0003DMT400065101; PGSC0003DMG400025302.
DR GeneID; 102596832; -.
DR Gramene; PGSC0003DMT400065101; PGSC0003DMT400065101; PGSC0003DMG400025302.
DR KEGG; sot:102596832; -.
DR eggNOG; ENOG502QT6H; Eukaryota.
DR HOGENOM; CLU_031507_1_1_1; -.
DR InParanoid; M1CDE5; -.
DR OMA; IEMGANH; -.
DR OrthoDB; 449324at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR ExpressionAtlas; M1CDE5; baseline.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0047480; F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR Gene3D; 3.90.190.20; Mur ligase, C-terminal domain; 1.
DR Gene3D; 3.40.1190.10; Mur-like, catalytic domain; 1.
DR Gene3D; 3.40.1390.10; MurE/MurF, N-terminal domain; 1.
DR HAMAP; MF_02019; MurF; 1.
DR InterPro; IPR036565; Mur-like_cat_sf.
DR InterPro; IPR004101; Mur_ligase_C.
DR InterPro; IPR036615; Mur_ligase_C_dom_sf.
DR InterPro; IPR013221; Mur_ligase_cen.
DR InterPro; IPR035911; MurE/MurF_N.
DR InterPro; IPR005863; UDP-N-AcMur_synth.
DR NCBIfam; TIGR01143; murF; 1.
DR PANTHER; PTHR43024; UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE; 1.
DR PANTHER; PTHR43024:SF1; UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE; 1.
DR Pfam; PF02875; Mur_ligase_C; 1.
DR Pfam; PF08245; Mur_ligase_M; 1.
DR SUPFAM; SSF53623; MurD-like peptide ligases, catalytic domain; 1.
DR SUPFAM; SSF53244; MurD-like peptide ligases, peptide-binding domain; 1.
DR SUPFAM; SSF63418; MurE/MurF N-terminal domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000011115}.
FT DOMAIN 154..341
FT /note="Mur ligase central"
FT /evidence="ECO:0000259|Pfam:PF08245"
FT DOMAIN 361..437
FT /note="Mur ligase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02875"
SQ SEQUENCE 517 AA; 55568 MW; 31872DABA8994207 CRC64;
MSPLTIQLHS SVFPLTNPAK PQTTIFTLPS RPRILIPQAT FSSSSNSPLW TISEIVRAVN
GRIIKWGPPG TICTDTRTLE PGQWFLPLVG QNFDAHNFIT SKLATKGCVG VIGNWVCEGW
NNGFVQVEGD TMSSLKRLGF YARNMFTGCL IGLTGSVGKT TTKTMVALAL ESVGAIYYSP
GNWNNEIGVA LSLIGMSRDV GFGVLEMGMS KKGEILELSR MCRPDVRVIL NVNAAHLENF
ANLEEVSVAK GEILREAMPG HVCVLNGDDP LVMSLPVPVG VKKVVFGRKL GCDVRLVSSQ
IIDGGRRIQI VLEGFNETVK FIISSPGLHL AVNACAAAAV ASALGIPLAL AGNSLSRFIP
VHRRSELEVT ENGITIINDV YNASPASTQA AIDLLRNIDC KGKRVAILGD MLELGPTEFK
FHELMLQSCC DAHFDIVALV GTRFVSAAGS IDFGPEIKLL CTTNAHQMTS KIINDLNSGD
VVLVKGSRQI GMEVIVDAIK SIHFAVPLCH AVMSKCD
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