ID   M1CN94_SOLTU            Unreviewed;       533 AA.
AC   M1CN94;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=FH protein NFH2 {ECO:0000313|EnsemblPlants:PGSC0003DMT400071148};
GN   Name=102591335 {ECO:0000313|EnsemblPlants:PGSC0003DMT400071148};
OS   Solanum tuberosum (Potato).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX   NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400071148, ECO:0000313|Proteomes:UP000011115};
RN   [1] {ECO:0000313|Proteomes:UP000011115}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX   PubMed=21743474; DOI=10.1038/nature10158;
RG   The Potato Genome Sequencing Consortium;
RT   "Genome sequence and analysis of the tuber crop potato.";
RL   Nature 475:189-195(2011).
RN   [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400071148}
RP   IDENTIFICATION.
RC   STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400071148};
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the formin-like family. Class-I subfamily.
CC       {ECO:0000256|ARBA:ARBA00025793}.
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DR   AlphaFoldDB; M1CN94; -.
DR   EnsemblPlants; PGSC0003DMT400071148; PGSC0003DMT400071148; PGSC0003DMG400027669.
DR   Gramene; PGSC0003DMT400071148; PGSC0003DMT400071148; PGSC0003DMG400027669.
DR   HOGENOM; CLU_511338_0_0_1; -.
DR   Proteomes; UP000011115; Unassembled WGS sequence.
DR   ExpressionAtlas; M1CN94; baseline.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   GO; GO:0045010; P:actin nucleation; IEA:InterPro.
DR   Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   InterPro; IPR027643; Formin-like_plant.
DR   PANTHER; PTHR23213:SF276; FORMIN-LIKE PROTEIN 1; 1.
DR   PANTHER; PTHR23213; FORMIN-RELATED; 1.
DR   PROSITE; PS51444; FH2; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        122..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          492..533
FT                   /note="FH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51444"
FT   REGION          43..88
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          148..186
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          203..246
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          298..464
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          485..505
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        43..64
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        65..82
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        203..227
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        298..328
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        347..383
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        387..401
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        421..461
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   533 AA;  57645 MW;  121B65DAEEB4C24B CRC64;
     MVVSFFFIFF LCFSPQYYYL SFATTAAAVF SGNNRRVLHE PFFPLDSPPP SSQPPIPSPP
     APTEYPFQGS TTTPDNSDNN PFFPTYPSPP LPPDSPADFV PANVSSIILP NTSKSNPVSN
     KLIVTAIISV LAAVIVLSIA IFLHIRKRRK QSDRKTQRSD SNSNGLSRDG ARSDGNNGVP
     KLQRPSQTSS EFLYLGTLAS SHGGVETHNA QNRNGSNTSS TPSSRKMDSP ELRPLPPLHG
     RNLRQSYGNT RFFSGTAEND VDFYSSAGSM GGRESSIGGD SLSRRDFSAV EVEKFVGCSS
     SSSSSSSSSG SGSPVRSVSL SISPPASLSP ERKSVRPKSP ELVAVDTAPP PQYPPPPPPP
     PATIVPPFAE SPSPSPSPPC PLSPERYSTR SMDSSPGIFN LLDQDVQFPA RIRNHIQQAT
     PAFGPPPPRP PPPPPPRSKN MESPKTPSPP FSKPAFNPPV LESPLKPIGI ESPVLVSPME
     LPSISEHIEK NDEKTEEPKP KLKTLHWDKV RASSDREMVW DQLKSSSFKY DNL
//