ID M1D4P4_SOLTU Unreviewed; 877 AA.
AC M1D4P4;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=GTP diphosphokinase {ECO:0000256|ARBA:ARBA00013251};
DE EC=2.7.6.5 {ECO:0000256|ARBA:ARBA00013251};
GN Name=102606017 {ECO:0000313|EnsemblPlants:PGSC0003DMT400081393};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400081393, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400081393}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400081393};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RelA/SpoT family.
CC {ECO:0000256|ARBA:ARBA00007476}.
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DR RefSeq; XP_006359863.1; XM_006359801.2.
DR AlphaFoldDB; M1D4P4; -.
DR STRING; 4113.M1D4P4; -.
DR PaxDb; 4113-PGSC0003DMT400081393; -.
DR EnsemblPlants; PGSC0003DMT400081393; PGSC0003DMT400081393; PGSC0003DMG400031817.
DR GeneID; 102606017; -.
DR Gramene; PGSC0003DMT400081393; PGSC0003DMT400081393; PGSC0003DMG400031817.
DR KEGG; sot:102606017; -.
DR eggNOG; KOG1157; Eukaryota.
DR HOGENOM; CLU_012300_5_0_1; -.
DR InParanoid; M1D4P4; -.
DR OMA; HSIQWFC; -.
DR OrthoDB; 1396at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR ExpressionAtlas; M1D4P4; baseline and differential.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0008728; F:GTP diphosphokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR CDD; cd05399; NT_Rel-Spo_like; 1.
DR CDD; cd01668; TGS_RSH; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR007685; RelA_SpoT.
DR InterPro; IPR004095; TGS.
DR InterPro; IPR012676; TGS-like.
DR InterPro; IPR033655; TGS_RelA/SpoT.
DR PANTHER; PTHR43061; GTP DIPHOSPHOKINASE RSH1, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR43061:SF1; GTP DIPHOSPHOKINASE RSH1, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF13328; HD_4; 1.
DR Pfam; PF04607; RelA_SpoT; 1.
DR Pfam; PF02824; TGS; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00954; RelA_SpoT; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81271; TGS-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS51880; TGS; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plastid {ECO:0000256|ARBA:ARBA00022640};
KW Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Transferase {ECO:0000256|ARBA:ARBA00022777}.
FT DOMAIN 167..273
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT DOMAIN 556..619
FT /note="TGS"
FT /evidence="ECO:0000259|PROSITE:PS51880"
FT COILED 324..355
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 877 AA; 97932 MW; C42D2B2B170EC06E CRC64;
MASATSMSVS IECVNICKSW KGDVSGRLDC SALSCAWKAP RALTGFLAST THPTQCSSTR
FGRYGRRDRL RRCRCYTSDM DERYPVEVLR GVPGSMLLLS ASSKWKLCCS SSFSSESYVA
ISPESLWEDL KPTISYLSCK ELELVRKALN LAFEAHDGQK RRSGEPFIIH PVAVAQILGQ
LELDWESVAA GLLHDTVEDT DVVTFERIEK EFGATVRRIV EGETKVSKLG KIKCKDESHV
QDVKADDLRQ MFLSMTEEVR VIIVKLADRL HNMRTLSHMP PHKQSGIATE TLQVFAPLAK
LLGIYQIKSE LENLAFMYTN AQDYARVQRR IAELYKEHEK EIEEAKRILM KKIEEDQFLE
LVTVKTEIQS ICKEPYSIYK AVLKSKSSIN EVNQIAQLRI IIKPKPCVGV RPLCNAQQIC
YHLLGLVHGI WTPIPRAMKD YIATPKPNGY QSLHTTVIPF LYESMFRLEV QIRTEEMDLI
AERGIAAHYS GKGFVNGLVG HVITNDKSSG GKIVCLNNAN IALRIGWLNA IREWQEEFVG
NMSSREFVDT VTRDLLGSRV FVFTPGGEIK HLPKGATVID YAYMIHTEIG NKMVAAKVNG
NLVKPMHVLA NAEVVEIITY NGLSSKSAFE RHKQWLQHAK TRCARHKIMK FLREQAALSA
SEITVDSVKE FAAESEGDST VEELADYSKG TKHSWEKILK NVMEVSSARI NSEDIFQLRS
GSIQIPKVNG KHNKCMQHTS LKATGETLSQ GNGVGEMILA NIPRYRDVLP GLDGWLASKV
ATWQNLEGHS VQWFCVVSID RKGMMADITS ALAAVGVTIC SCAAETDREK GIGVALFHIE
ADLESLVGAS LKIDMILGVL GWSTGCSWSE NKQFLEC
//
