ID M1L557_9PROT Unreviewed; 494 AA.
AC M1L557;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=NADH dehydrogenase I subunit M {ECO:0000313|EMBL:AGF47773.1};
DE EC=1.6.5.3 {ECO:0000313|EMBL:AGF47773.1};
GN ORFNames=CDEE_0794 {ECO:0000313|EMBL:AGF47773.1};
OS Candidatus Kinetoplastibacterium crithidii TCC036E.
OC Bacteria; Pseudomonadota; Betaproteobacteria;
OC Candidatus Kinetoplastibacterium.
OX NCBI_TaxID=1208918 {ECO:0000313|EMBL:AGF47773.1, ECO:0000313|Proteomes:UP000011686};
RN [1] {ECO:0000313|EMBL:AGF47773.1, ECO:0000313|Proteomes:UP000011686}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TCC036E {ECO:0000313|EMBL:AGF47773.1,
RC ECO:0000313|Proteomes:UP000011686};
RX PubMed=23345457;
RA Alves J.M., Serrano M.G., Maia da Silva F., Voegtly L.J., Matveyev A.V.,
RA Teixeira M.M., Camargo E.P., Buck G.A.;
RT "Genome evolution and phylogenomic analysis of candidatus
RT kinetoplastibacterium, the betaproteobacterial endosymbionts of strigomonas
RT and angomonas.";
RL Genome Biol. Evol. 5:338-350(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}.
CC -!- SIMILARITY: Belongs to the complex I subunit 4 family.
CC {ECO:0000256|ARBA:ARBA00009025}.
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DR EMBL; CP003804; AGF47773.1; -; Genomic_DNA.
DR AlphaFoldDB; M1L557; -.
DR STRING; 1208918.CDEE_0794; -.
DR KEGG; kct:CDEE_0794; -.
DR PATRIC; fig|1208918.3.peg.473; -.
DR eggNOG; COG1008; Bacteria.
DR HOGENOM; CLU_007100_4_4_4; -.
DR Proteomes; UP000011686; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR InterPro; IPR010227; NADH_Q_OxRdtase_chainM/4.
DR InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR InterPro; IPR001750; ND/Mrp_mem.
DR NCBIfam; TIGR01972; NDH_I_M; 1.
DR PANTHER; PTHR43507; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; 1.
DR PANTHER; PTHR43507:SF20; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR PRINTS; PR01437; NUOXDRDTASE4.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:AGF47773.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011686};
KW Transmembrane {ECO:0000256|RuleBase:RU000320, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 33..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 135..417
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 494 AA; 55826 MW; A481CD23838F9BC5 CRC64;
MSYTSIPWLS LSIFTPIVFG FIILAVDRRN QLYIKLISLF GSIISLFIVL SIYKLFQIDS
SLFQFEENYS WIETFNINYH LGIDGISLWF LILNSFMTVI VILSSWESIK NNISQYFAAF
LILSGLINGV FVSLDGILFY VFFETTLIPM YLIIGIWGGP NRFYASFKFF LYTLLGSLLM
FIALIYLRNI SNSSEIINWY SINIRYIDQV LIFMAFWLAF AVKIPMWPVH TWLPDAHVEA
PTGGSIILAS IMLKLGAYGF LRFSLPILPD ASKDMSILMI SLSLIAIIYI GFIAIAQRDM
KKLIAYSSIA HMGFVTLGIF IFNKAGMEGA ILQMISHGFV STAMFFSIGV LYDRTHSRLI
SDYSGLVNVM PTFVTFFVFF SMANSGLPVT SGFVGEFFVI MGSIKYNFVV GILTALSLVL
SASYSLWLVK RIAFGKINSS TASNNLSDVN KREFFIFSLL AILILFMGIY PKIFTDVIHL
PVEILLDQLS ITKI
//
