ID M1LU68_9CLOT Unreviewed; 448 AA.
AC M1LU68;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=CCA-adding enzyme Cca {ECO:0000313|EMBL:AGF56605.1};
DE EC=2.7.7.72 {ECO:0000313|EMBL:AGF56605.1};
GN Name=cca {ECO:0000313|EMBL:AGF56605.1};
GN ORFNames=Cspa_c28420 {ECO:0000313|EMBL:AGF56605.1};
OS Clostridium saccharoperbutylacetonicum N1-4(HMT).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=931276 {ECO:0000313|EMBL:AGF56605.1, ECO:0000313|Proteomes:UP000011728};
RN [1] {ECO:0000313|EMBL:AGF56605.1, ECO:0000313|Proteomes:UP000011728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N1-4(HMT) {ECO:0000313|Proteomes:UP000011728};
RA Poehlein A., Daniel R.;
RT "Genome sequence of Clostridium saccharoperbutylacetonicum N1-4(HMT).";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the tRNA nucleotidyltransferase/poly(A)
CC polymerase family. {ECO:0000256|RuleBase:RU003953}.
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DR EMBL; CP004121; AGF56605.1; -; Genomic_DNA.
DR RefSeq; WP_015392924.1; NZ_AOIF01000093.1.
DR AlphaFoldDB; M1LU68; -.
DR STRING; 36745.CLSAP_25950; -.
DR KEGG; csr:Cspa_c28420; -.
DR PATRIC; fig|931276.5.peg.2858; -.
DR eggNOG; COG0617; Bacteria.
DR HOGENOM; CLU_015961_3_1_9; -.
DR OrthoDB; 9805698at2; -.
DR Proteomes; UP000011728; Chromosome.
DR GO; GO:0004810; F:CCA tRNA nucleotidyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0031123; P:RNA 3'-end processing; IEA:UniProt.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR CDD; cd05398; NT_ClassII-CCAase; 1.
DR Gene3D; 1.10.246.80; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3090.10; cca-adding enzyme, domain 2; 1.
DR InterPro; IPR032810; CCA-adding_enz_C.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002646; PolA_pol_head_dom.
DR InterPro; IPR032828; PolyA_RNA-bd.
DR PANTHER; PTHR46173; CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR46173:SF1; CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL; 1.
DR Pfam; PF01743; PolyA_pol; 1.
DR Pfam; PF12627; PolyA_pol_RNAbd; 1.
DR Pfam; PF13735; tRNA_NucTran2_2; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81891; Poly A polymerase C-terminal region-like; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:AGF56605.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011728};
KW RNA-binding {ECO:0000256|RuleBase:RU003953};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003953}.
FT DOMAIN 25..144
FT /note="Poly A polymerase head"
FT /evidence="ECO:0000259|Pfam:PF01743"
FT DOMAIN 172..229
FT /note="tRNA nucleotidyltransferase/poly(A) polymerase RNA
FT and SrmB- binding"
FT /evidence="ECO:0000259|Pfam:PF12627"
FT DOMAIN 297..435
FT /note="CCA-adding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13735"
SQ SEQUENCE 448 AA; 52112 MW; 79C47C63E259F9EC CRC64;
MNIEINMPEN VKYIINTLMT NGYEAYVVGG CVRDSILNRE PKDWDITTKA KPEEVINLFD
KVILTGLKHG TVTVIINKEN YEITTYRTDG EYEDNRHPKE VKFVNSLKED LARRDFTINA
MAYNERDGLI DYFNGVKDLN SKIINTVGEA KKRFEEDALR MLRAIRFSAQ LNFEINYNVL
EAIKDLKDNL RKISKERIRE EFNKTIVYNP RKLQLLKDTE TFEYIIEGIS SIYDFDQNNP
YHSYDLYEHT LLATEAIEPI IHLRLTMLLH DLGKVVTKTT DEKGISHFYA HPRESLKIAE
KILGTLKYDN NTTNKVLTLI EYHDCTLKSK VSIKRMLNKI GEELFRDLLR VKWADALAQN
PKYFKDTVKN LLEVDEKLNI IIKERECFSV KDLKINGEEL IALGFNKGKE IGETLKYLLN
EVIANPELNK KSELIKLSEA RLNENSII
//
