ID M1UXW1_CYAM1 Unreviewed; 720 AA.
AC M1UXW1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Transcription factor E2F {ECO:0000313|EMBL:BAM83371.1};
GN ORFNames=CYME_CMT433C {ECO:0000313|EMBL:BAM83371.1};
OS Cyanidioschyzon merolae (strain NIES-3377 / 10D) (Unicellular red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Cyanidiales; Cyanidiaceae;
OC Cyanidioschyzon.
OX NCBI_TaxID=280699 {ECO:0000313|EMBL:BAM83371.1, ECO:0000313|Proteomes:UP000007014};
RN [1] {ECO:0000313|EMBL:BAM83371.1, ECO:0000313|Proteomes:UP000007014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10D {ECO:0000313|EMBL:BAM83371.1,
RC ECO:0000313|Proteomes:UP000007014};
RX PubMed=15071595; DOI=10.1038/nature02398;
RA Matsuzaki M., Misumi O., Shin-i T., Maruyama S., Takahara M.,
RA Miyagishima S., Mori T., Nishida K., Yagisawa F., Nishida K., Yoshida Y.,
RA Nishimura Y., Nakao S., Kobayashi T., Momoyama Y., Higashiyama T.,
RA Minoda A., Sano M., Nomoto H., Oishi K., Hayashi H., Ohta F., Nishizaka S.,
RA Haga S., Miura S., Morishita T., Kabeya Y., Terasawa K., Suzuki Y.,
RA Ishii Y., Asakawa S., Takano H., Ohta N., Kuroiwa H., Tanaka K.,
RA Shimizu N., Sugano S., Sato N., Nozaki H., Ogasawara N., Kohara Y.,
RA Kuroiwa T.;
RT "Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon
RT merolae 10D.";
RL Nature 428:653-657(2004).
RN [2] {ECO:0000313|EMBL:BAM83371.1, ECO:0000313|Proteomes:UP000007014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10D {ECO:0000313|EMBL:BAM83371.1,
RC ECO:0000313|Proteomes:UP000007014};
RX PubMed=17623057; DOI=10.1186/1741-7007-5-28;
RA Nozaki H., Takano H., Misumi O., Terasawa K., Matsuzaki M., Maruyama S.,
RA Nishida K., Yagisawa F., Yoshida Y., Fujiwara T., Takio S., Tamura K.,
RA Chung S.J., Nakamura S., Kuroiwa H., Tanaka K., Sato N., Kuroiwa T.;
RT "A 100%-complete sequence reveals unusually simple genomic features in the
RT hot-spring red alga Cyanidioschyzon merolae.";
RL BMC Biol. 5:28-28(2007).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU003796}. Plastid,
CC chloroplast {ECO:0000256|ARBA:ARBA00004229}.
CC -!- SIMILARITY: Belongs to the E2F/DP family.
CC {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|RuleBase:RU003796}.
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DR EMBL; AP006502; BAM83371.1; -; Genomic_DNA.
DR RefSeq; XP_005539407.1; XM_005539350.1.
DR AlphaFoldDB; M1UXW1; -.
DR STRING; 280699.M1UXW1; -.
DR EnsemblPlants; CMT433CT; CMT433CT; CMT433C.
DR GeneID; 16998230; -.
DR Gramene; CMT433CT; CMT433CT; CMT433C.
DR KEGG; cme:CYME_CMT433C; -.
DR eggNOG; KOG2578; Eukaryota.
DR HOGENOM; CLU_384223_0_0_1; -.
DR OrthoDB; 1761at2759; -.
DR Proteomes; UP000007014; Chromosome 20.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR015633; E2F.
DR InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12081; TRANSCRIPTION FACTOR E2F; 1.
DR PANTHER; PTHR12081:SF7; TRANSCRIPTION FACTOR EFL-3; 1.
DR Pfam; PF02319; E2F_TDP; 2.
DR SMART; SM01372; E2F_TDP; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003796};
KW Nucleus {ECO:0000256|RuleBase:RU003796};
KW Reference proteome {ECO:0000313|Proteomes:UP000007014};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU003796};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU003796}.
FT DOMAIN 33..104
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT DOMAIN 190..278
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 123..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 389..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 651..720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..708
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 720 AA; 77632 MW; 25F69977B2E07D86 CRC64;
MFPYRASPMR GYGEPGTSRS SSQPLVSGDA YSRKDKSLGL LCENFLSLYG VLEQARGNSS
CEICLDEAAT RLGVERRRIY DIVNVLESVG MVTRKAKNKY IWLGQSRLKE SIQRLRQEAE
SAGGVAGLGD SSQLNGDDDE LANDPVSGPL STTAKASEVE RYATCPESLL ASNALSKPSV
ASTKNHRMSR KEKSLGALSQ RFVQLFLLAG GDTISLEYAA SILLSGSVGN REAEENPLNG
GMKTKVRRLY DIANILSSLG LIRKTHTEYR KPAFVWCGED NVRLEELRTP RELLPNPYSN
QVVRPASADK LQAAGLTDAA IARSTQRLPS LHSTNEALRY ASCALPGTDS VADGAWLAVA
NAEDPAAYVN TVMPSFQEMR VPDGHELREI SSPKRPRTAN AALTENKEDR AAWPGLAAAP
GAPRGMTSTA SRSVLNPRPL FPRPSSVPPS PVRGLGNRSV PPSPGALPAV QGMPRTDAAV
PAACGYPSNM PSRGPTSPEH VALWGWSPLP GPFSAKLYAA HGMSPHALGS SYTLTSNTPA
NYIHSSGQAA SQWLEWLDHV QQQQQQQQLQ QQQPQQQVTG WKGFGSRPNT PPSYSFHFDI
DAYMRRAQAA GPEYYARAQE WYREMLEWKQ RWLRPAGAAP VAATAASPIP SSLETAGMQN
GQHAAAGSDQ QRHPRLNGSA TRAMDASRST HDVQDASPVE SPATASTMAA MEATLAPPTN
//
