ID M1VC31_CYAM1 Unreviewed; 549 AA.
AC M1VC31;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Probable zinc protease {ECO:0000313|EMBL:BAM80017.1};
GN ORFNames=CYME_CMI130C {ECO:0000313|EMBL:BAM80017.1};
OS Cyanidioschyzon merolae (strain NIES-3377 / 10D) (Unicellular red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Cyanidiales; Cyanidiaceae;
OC Cyanidioschyzon.
OX NCBI_TaxID=280699 {ECO:0000313|EMBL:BAM80017.1, ECO:0000313|Proteomes:UP000007014};
RN [1] {ECO:0000313|EMBL:BAM80017.1, ECO:0000313|Proteomes:UP000007014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10D {ECO:0000313|EMBL:BAM80017.1,
RC ECO:0000313|Proteomes:UP000007014};
RX PubMed=15071595; DOI=10.1038/nature02398;
RA Matsuzaki M., Misumi O., Shin-i T., Maruyama S., Takahara M.,
RA Miyagishima S., Mori T., Nishida K., Yagisawa F., Nishida K., Yoshida Y.,
RA Nishimura Y., Nakao S., Kobayashi T., Momoyama Y., Higashiyama T.,
RA Minoda A., Sano M., Nomoto H., Oishi K., Hayashi H., Ohta F., Nishizaka S.,
RA Haga S., Miura S., Morishita T., Kabeya Y., Terasawa K., Suzuki Y.,
RA Ishii Y., Asakawa S., Takano H., Ohta N., Kuroiwa H., Tanaka K.,
RA Shimizu N., Sugano S., Sato N., Nozaki H., Ogasawara N., Kohara Y.,
RA Kuroiwa T.;
RT "Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon
RT merolae 10D.";
RL Nature 428:653-657(2004).
RN [2] {ECO:0000313|EMBL:BAM80017.1, ECO:0000313|Proteomes:UP000007014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10D {ECO:0000313|EMBL:BAM80017.1,
RC ECO:0000313|Proteomes:UP000007014};
RX PubMed=17623057; DOI=10.1186/1741-7007-5-28;
RA Nozaki H., Takano H., Misumi O., Terasawa K., Matsuzaki M., Maruyama S.,
RA Nishida K., Yagisawa F., Yoshida Y., Fujiwara T., Takio S., Tamura K.,
RA Chung S.J., Nakamura S., Kuroiwa H., Tanaka K., Sato N., Kuroiwa T.;
RT "A 100%-complete sequence reveals unusually simple genomic features in the
RT hot-spring red alga Cyanidioschyzon merolae.";
RL BMC Biol. 5:28-28(2007).
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
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DR EMBL; AP006491; BAM80017.1; -; Genomic_DNA.
DR RefSeq; XP_005536303.1; XM_005536246.1.
DR AlphaFoldDB; M1VC31; -.
DR STRING; 280699.M1VC31; -.
DR EnsemblPlants; CMI130CT; CMI130CT; CMI130C.
DR GeneID; 16993761; -.
DR Gramene; CMI130CT; CMI130CT; CMI130C.
DR KEGG; cme:CYME_CMI130C; -.
DR eggNOG; KOG0960; Eukaryota.
DR HOGENOM; CLU_009902_1_2_1; -.
DR OMA; TSFERTN; -.
DR OrthoDB; 306122at2759; -.
DR Proteomes; UP000007014; Chromosome 9.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR001431; Pept_M16_Zn_BS.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR43690:SF18; INSULIN-DEGRADING ENZYME-RELATED; 1.
DR PANTHER; PTHR43690; NARDILYSIN; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR PROSITE; PS00143; INSULINASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:BAM80017.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007014};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 107..153
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 305..483
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 549 AA; 62606 MW; 7FCF017BDE81320B CRC64;
MGILPFCNAT AAERFCQSPK RTQTKRRTRY QGSRERRRRG YVFASGSVCS RRRFLSYVFS
SAGVLLGQKA ANAGATTTTK VPSLKDFLTE QMRGLHQFQL PNGARFVVLE RSNTPTVSFI
SFVDAGAVDE TDGKTGMAHF LEHLAFKGSR QIGTNNWAAE SRLLCDLDRL YDKWHADPEA
VHEQIMTLSR EAEAFVDENA FGRLVQRNGG IGLNAATEAD TTQYFYNLPA NRTELWFALE
SERFRDPVFR EFERERRVIL EERLLRVDND DVGKFLEEFL EVAFEKHPYR RPVIGYKEDI
QRLVPADVRS FFREFYVPTR LTFVIVGDVK HQVIHDLAVR YFADLPGTGA SRRQIPRYPR
EYSPQSPKHF QIDLASNPMC LVAYHVPPFQ DPDTAALRVL SDMLDGGRLS RLYKLFIETG
KASSANFSLG FPGDKYVNLG IFSALPIPGQ DMQRIVDEWH TAAAHLQNPA NITDKELERV
RKRVRVSLLN AIMNNNEMAG LLGKFALMKG DARELFRFLD RLEAVRREDV SRVAALYLKP
EHSITGFMV
//
