ID M1VEQ8_CYAM1 Unreviewed; 1026 AA.
AC M1VEQ8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 03-MAY-2023, entry version 44.
DE SubName: Full=Acetyl-CoA synthetase {ECO:0000313|EMBL:BAM81402.1};
GN ORFNames=CYME_CMN336C {ECO:0000313|EMBL:BAM81402.1};
OS Cyanidioschyzon merolae (strain NIES-3377 / 10D) (Unicellular red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Cyanidiales; Cyanidiaceae;
OC Cyanidioschyzon.
OX NCBI_TaxID=280699 {ECO:0000313|EMBL:BAM81402.1, ECO:0000313|Proteomes:UP000007014};
RN [1] {ECO:0000313|EMBL:BAM81402.1, ECO:0000313|Proteomes:UP000007014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10D {ECO:0000313|EMBL:BAM81402.1,
RC ECO:0000313|Proteomes:UP000007014};
RX PubMed=15071595; DOI=10.1038/nature02398;
RA Matsuzaki M., Misumi O., Shin-i T., Maruyama S., Takahara M.,
RA Miyagishima S., Mori T., Nishida K., Yagisawa F., Nishida K., Yoshida Y.,
RA Nishimura Y., Nakao S., Kobayashi T., Momoyama Y., Higashiyama T.,
RA Minoda A., Sano M., Nomoto H., Oishi K., Hayashi H., Ohta F., Nishizaka S.,
RA Haga S., Miura S., Morishita T., Kabeya Y., Terasawa K., Suzuki Y.,
RA Ishii Y., Asakawa S., Takano H., Ohta N., Kuroiwa H., Tanaka K.,
RA Shimizu N., Sugano S., Sato N., Nozaki H., Ogasawara N., Kohara Y.,
RA Kuroiwa T.;
RT "Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon
RT merolae 10D.";
RL Nature 428:653-657(2004).
RN [2] {ECO:0000313|EMBL:BAM81402.1, ECO:0000313|Proteomes:UP000007014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10D {ECO:0000313|EMBL:BAM81402.1,
RC ECO:0000313|Proteomes:UP000007014};
RX PubMed=17623057; DOI=10.1186/1741-7007-5-28;
RA Nozaki H., Takano H., Misumi O., Terasawa K., Matsuzaki M., Maruyama S.,
RA Nishida K., Yagisawa F., Yoshida Y., Fujiwara T., Takio S., Tamura K.,
RA Chung S.J., Nakamura S., Kuroiwa H., Tanaka K., Sato N., Kuroiwa T.;
RT "A 100%-complete sequence reveals unusually simple genomic features in the
RT hot-spring red alga Cyanidioschyzon merolae.";
RL BMC Biol. 5:28-28(2007).
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DR EMBL; AP006496; BAM81402.1; -; Genomic_DNA.
DR RefSeq; XP_005537438.1; XM_005537381.1.
DR AlphaFoldDB; M1VEQ8; -.
DR STRING; 280699.M1VEQ8; -.
DR EnsemblPlants; CMN336CT; CMN336CT; CMN336C.
DR GeneID; 16995212; -.
DR Gramene; CMN336CT; CMN336CT; CMN336C.
DR KEGG; cme:CYME_CMN336C; -.
DR eggNOG; ENOG502QWQW; Eukaryota.
DR HOGENOM; CLU_007415_0_2_1; -.
DR OMA; IVIYMES; -.
DR OrthoDB; 5474939at2759; -.
DR Proteomes; UP000007014; Chromosome 14.
DR GO; GO:0043758; F:acetate-CoA ligase (ADP-forming) activity; IEA:InterPro.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR003781; CoA-bd.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR043938; Ligase_CoA_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR43334; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR PANTHER; PTHR43334:SF1; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR Pfam; PF13302; Acetyltransf_3; 1.
DR Pfam; PF13549; ATP-grasp_5; 1.
DR Pfam; PF13380; CoA_binding_2; 1.
DR Pfam; PF19045; Ligase_CoA_2; 1.
DR Pfam; PF13607; Succ_CoA_lig; 1.
DR SMART; SM00881; CoA_binding; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS51186; GNAT; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Reference proteome {ECO:0000313|Proteomes:UP000007014}.
FT DOMAIN 612..648
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT DOMAIN 856..1026
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
SQ SEQUENCE 1026 AA; 110980 MW; A3FE6736DBDD619B CRC64;
MLNCSRELGR ATLATVWQKG QVSGLRAWYA QVTACDAAGG YRLGGKRLIT QLISPADSVG
SRKMGVPTAV SVQRLSSSCA GETGTAASER SASVPRFDPS VHIVTRRTRV REQLDAIFKP
RAVAVIGATE KPGSVGRNIF QNLLSPFGGA VYPVNPKRSH ILGIRAYPNV SSIPEPIDLA
VITTPARTVP SIMHELADNR VPGCVIISAG FAEAQVGGEG RKLLDETLAE ARRGGTRIIG
PNCLGILNIS TGMNASFGAR AEYVKGDVAL LSQSGALVCS LLDWALKERF GFSKVASLGT
MCDVDWADMI RYIGEDTHSR SIVAYVESIG NVRAFISAAR EVATTKPIVV IKAGRTPAAA
AAAASHTGNL TGSDEVIGEV LRRAGVLRVD RIDDLFLTAR VLAQQPRPRG KNLTIITNAG
GPGILAADEL VSGGGALTEL SSETMDALDK VLPAAWSHAN PVDIIGDATP ETYAKALEIC
SKDVNTDGTL VILTPQVMTD ATATADILVR AAATARAEDK PVLASWMGGI DVLAGQEILK
RNEIPNFAFA DVAVRIWNYL HRYNSILESL YEVPEGPSTR VAGMRQIKRS AEEMLEQARQ
AGRIVLNEYE SKRLLSMYEI PVLEAKLAHS EDEAVEIAKR IGFPVVAKLL SHTITHKTDV
GGVKVNLHTP DQVVEAFHSI RESVTKLRGA EHFQGVILER MIDLRPGGYE VLLGSTLDPQ
AGPIVAFGTG GTLVEVYRDV SLGIPPLNSA LARQMMERTR IYNALKGVRG HDPADLEQLQ
TVVSRFSRMV CEQRLIKECD INPLFVTPRG IVAIDARVVL HDPHVSLDTV PQPAIRPYPS
EYVSPWSGDS MGNLPVVIRP IHPSDTPKLL EFWDALSTTG TGYLVPQVVA AAPTRDVNLR
DRWLRNRLLR IAFCDFNSEM VIIAEARDAE GSAAIHALAQ LRLEPEPDPG HFAINVLDTD
RGHGLGTEML RRLMDIARRE GLTRIWSEIA PENRAMQRIC EKLGFQLGPL PDQENGNILA
EYVLSA
//
