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Database: UniProt
Entry: M1VGB6_CYAM1
LinkDB: M1VGB6_CYAM1
Original site: M1VGB6_CYAM1 
ID   M1VGB6_CYAM1            Unreviewed;       339 AA.
AC   M1VGB6;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   28-MAR-2018, entry version 25.
DE   SubName: Full=Glyoxylate reductase/hydroxypyruvate reductase {ECO:0000313|EMBL:BAM82167.1};
GN   ORFNames=CYME_CMQ289C {ECO:0000313|EMBL:BAM82167.1};
OS   Cyanidioschyzon merolae (strain 10D) (Red alga).
OC   Eukaryota; Rhodophyta; Bangiophyceae; Cyanidiales; Cyanidiaceae;
OC   Cyanidioschyzon.
OX   NCBI_TaxID=280699 {ECO:0000313|EMBL:BAM82167.1, ECO:0000313|Proteomes:UP000007014};
RN   [1] {ECO:0000313|EMBL:BAM82167.1, ECO:0000313|Proteomes:UP000007014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=10D {ECO:0000313|EMBL:BAM82167.1,
RC   ECO:0000313|Proteomes:UP000007014};
RX   PubMed=15071595; DOI=10.1038/nature02398;
RA   Matsuzaki M., Misumi O., Shin-i T., Maruyama S., Takahara M.,
RA   Miyagishima S., Mori T., Nishida K., Yagisawa F., Nishida K.,
RA   Yoshida Y., Nishimura Y., Nakao S., Kobayashi T., Momoyama Y.,
RA   Higashiyama T., Minoda A., Sano M., Nomoto H., Oishi K., Hayashi H.,
RA   Ohta F., Nishizaka S., Haga S., Miura S., Morishita T., Kabeya Y.,
RA   Terasawa K., Suzuki Y., Ishii Y., Asakawa S., Takano H., Ohta N.,
RA   Kuroiwa H., Tanaka K., Shimizu N., Sugano S., Sato N., Nozaki H.,
RA   Ogasawara N., Kohara Y., Kuroiwa T.;
RT   "Genome sequence of the ultrasmall unicellular red alga
RT   Cyanidioschyzon merolae 10D.";
RL   Nature 428:653-657(2004).
RN   [2] {ECO:0000313|EMBL:BAM82167.1, ECO:0000313|Proteomes:UP000007014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=10D {ECO:0000313|EMBL:BAM82167.1,
RC   ECO:0000313|Proteomes:UP000007014};
RX   PubMed=17623057; DOI=10.1186/1741-7007-5-28;
RA   Nozaki H., Takano H., Misumi O., Terasawa K., Matsuzaki M.,
RA   Maruyama S., Nishida K., Yagisawa F., Yoshida Y., Fujiwara T.,
RA   Takio S., Tamura K., Chung S.J., Nakamura S., Kuroiwa H., Tanaka K.,
RA   Sato N., Kuroiwa T.;
RT   "A 100%-complete sequence reveals unusually simple genomic features in
RT   the hot-spring red alga Cyanidioschyzon merolae.";
RL   BMC Biol. 5:28-28(2007).
CC   -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC       dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR   EMBL; AP006499; BAM82167.1; -; Genomic_DNA.
DR   RefSeq; XP_005538203.1; XM_005538146.1.
DR   ProteinModelPortal; M1VGB6; -.
DR   STRING; 45157.CMQ289CT; -.
DR   EnsemblPlants; CMQ289CT; CMQ289CT; CMQ289C.
DR   GeneID; 16996198; -.
DR   Gramene; CMQ289CT; CMQ289CT; CMQ289C.
DR   KEGG; cme:CYME_CMQ289C; -.
DR   KO; K00049; -.
DR   Proteomes; UP000007014; Chromosome 17.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR   InterPro; IPR029753; D-isomer_DH_CS.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00389; 2-Hacid_dh; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007014};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW   Pyruvate {ECO:0000313|EMBL:BAM82167.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007014}.
FT   DOMAIN        9    334       2-Hacid_dh. {ECO:0000259|Pfam:PF00389}.
FT   DOMAIN      120    303       2-Hacid_dh_C. {ECO:0000259|Pfam:PF02826}.
SQ   SEQUENCE   339 AA;  36667 MW;  73C0F175E929438A CRC64;
     MAATGIVRVL VTRQIQEEAL EYVRKQVPNV ELQVHPDEHQ SPARSELEAW LERGVDGLVC
     VIGDVIDEAL LTHDTQGRLR VVSTMSVGYN HIDVESCRQR GIAVGHTPDV LTETTADLAV
     GLAIATARRF REALQAVEQP GGWKSSWSPT WMCGTDVHGA TVGIIGLGRI GVAVARRLHH
     GFGCRILYHG TREKPVVAAE IGQARFCADL GELLAESDFV IPLCPLTQKT RNLINASSLR
     LMKKSAFLIN VSRGEIVDQD AVCDALEAEA LAGYGTDVTV PEPIPTDHRL LKTRGVTVLP
     HIGSATLQTR LAMARLCVEN LVAGVKGDPL PHPVPLHAE
//
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