ID M1WAJ3_CLAP2 Unreviewed; 771 AA.
AC M1WAJ3;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Glycosyl hydrolase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CPUR_04336 {ECO:0000313|EMBL:CCE30488.1};
OS Claviceps purpurea (strain 20.1) (Ergot fungus) (Sphacelia segetum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Claviceps.
OX NCBI_TaxID=1111077 {ECO:0000313|EMBL:CCE30488.1, ECO:0000313|Proteomes:UP000016801};
RN [1] {ECO:0000313|EMBL:CCE30488.1, ECO:0000313|Proteomes:UP000016801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=20.1 {ECO:0000313|EMBL:CCE30488.1,
RC ECO:0000313|Proteomes:UP000016801};
RX PubMed=23468653; DOI=10.1371/journal.pgen.1003323;
RA Schardl C.L., Young C.A., Hesse U., Amyotte S.G., Andreeva K., Calie P.J.,
RA Fleetwood D.J., Haws D.C., Moore N., Oeser B., Panaccione D.G.,
RA Schweri K.K., Voisey C.R., Farman M.L., Jaromczyk J.W., Roe B.A.,
RA O'Sullivan D.M., Scott B., Tudzynski P., An Z., Arnaoudova E.G.,
RA Bullock C.T., Charlton N.D., Chen L., Cox M., Dinkins R.D., Florea S.,
RA Glenn A.E., Gordon A., Gueldener U., Harris D.R., Hollin W., Jaromczyk J.,
RA Johnson R.D., Khan A.K., Leistner E., Leuchtmann A., Li C., Liu J., Liu J.,
RA Liu M., Mace W., Machado C., Nagabhyru P., Pan J., Schmid J., Sugawara K.,
RA Steiner U., Takach J.E., Tanaka E., Webb J.S., Wilson E.V., Wiseman J.L.,
RA Yoshida R., Zeng Z.;
RT "Plant-symbiotic fungi as chemical engineers: Multi-genome analysis of the
RT Clavicipitaceae reveals dynamics of alkaloid loci.";
RL PLoS Genet. 9:E1003323-E1003323(2013).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC {ECO:0000256|ARBA:ARBA00005641}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCE30488.1}.
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DR EMBL; CAGA01000022; CCE30488.1; -; Genomic_DNA.
DR AlphaFoldDB; M1WAJ3; -.
DR STRING; 1111077.M1WAJ3; -.
DR VEuPathDB; FungiDB:CPUR_04336; -.
DR eggNOG; ENOG502QPU8; Eukaryota.
DR HOGENOM; CLU_009024_0_1_1; -.
DR OrthoDB; 69117at2759; -.
DR PhylomeDB; M1WAJ3; -.
DR Proteomes; UP000016801; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:1901136; P:carbohydrate derivative catabolic process; IEA:UniProt.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProt.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProt.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR041036; GH5_C.
DR InterPro; IPR001547; Glyco_hydro_5.
DR InterPro; IPR018087; Glyco_hydro_5_CS.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR31308; -; 1.
DR PANTHER; PTHR31308:SF5; ERGOSTERYL-BETA-GLUCOSIDASE; 1.
DR Pfam; PF00150; Cellulase; 1.
DR Pfam; PF18564; Glyco_hydro_5_C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS00659; GLYCOSYL_HYDROL_F5; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000016801};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 71..129
FT /note="Glycoside hydrolase family 5"
FT /evidence="ECO:0000259|Pfam:PF00150"
FT DOMAIN 645..734
FT /note="Glycoside hydrolase family 5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18564"
FT REGION 565..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 574..595
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 771 AA; 87049 MW; 24E1DE65EED1F149 CRC64;
MASFRLTIED GQFRDGHSRQ VVLRGINVAG DAKLPSEPNR PSHISEGFFD GDSVKFHERP
FSKKDAPIHF ARLKRYGFNT IRYIFTWEAI ESAGPGIYDE DFIQHTIEIL RLAKSYGFFV
FMDPHQDVWS RFTGGSGAPM WTLYACGLNP RSFAATEAAI VQNTYPKPDD FPKMIWSTNY
HRLAAGTMFT LFFAGKDFAP KCIIDGMNIQ DYLQDHFCNA CAHLAKRIHE AGDLENDPVV
GWESMNEPNR GMVGYVDLTV TAKDNPLKKG TCPTMWQTFL TGMGRACEID TWEMGGLGPY
KTGRTLVDPR GQIAWLPEDY DDSRYGWKRH PEWKLGQCLW AQHGVWDTST DTILKKHYFS
VNPRTGKTID YPEFTNSYFM DFWRHYSRSC RAHHKNCIML MQYPTLELPP EIKGTEDDDP
MMAFTPHFYD GITLMTKHWN STWNVDVVGV LRGKYLHPAF AIKIGESAIR NCLRDQLASL
RQEGLDRTGK HPCLLTEFGI PYDMDEKKAF KTGDYSSQSA ALDANYFGVE RSQIEGHCLW
VYTVINDHER GDQWNGEDLS INSVDDKLPC TSPVPKSPTL SSSAESPLKL SSTNKNRESS
LDDEIITPGN LQHTLASPSI SSNRSAKDPE LTNAPGFRGA EAFIRPTPTV VAGNVSYTGF
DLRRCVYELK IRASKAAEET APTTVFVPEF HFPQDQCEVT VSAGKWELSS DDSEGPMLQR
LKWWHPEGEQ SLTVQGIVRK HNVAEGSTEE AGYLEQCQQG YGFNAGNCLV M
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