ID M1WHY1_CLAP2 Unreviewed; 446 AA.
AC M1WHY1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Fatty acid desaturase domain-containing protein {ECO:0000259|Pfam:PF00487};
GN ORFNames=CPUR_07444 {ECO:0000313|EMBL:CCE33519.1};
OS Claviceps purpurea (strain 20.1) (Ergot fungus) (Sphacelia segetum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Claviceps.
OX NCBI_TaxID=1111077 {ECO:0000313|EMBL:CCE33519.1, ECO:0000313|Proteomes:UP000016801};
RN [1] {ECO:0000313|EMBL:CCE33519.1, ECO:0000313|Proteomes:UP000016801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=20.1 {ECO:0000313|EMBL:CCE33519.1,
RC ECO:0000313|Proteomes:UP000016801};
RX PubMed=23468653; DOI=10.1371/journal.pgen.1003323;
RA Schardl C.L., Young C.A., Hesse U., Amyotte S.G., Andreeva K., Calie P.J.,
RA Fleetwood D.J., Haws D.C., Moore N., Oeser B., Panaccione D.G.,
RA Schweri K.K., Voisey C.R., Farman M.L., Jaromczyk J.W., Roe B.A.,
RA O'Sullivan D.M., Scott B., Tudzynski P., An Z., Arnaoudova E.G.,
RA Bullock C.T., Charlton N.D., Chen L., Cox M., Dinkins R.D., Florea S.,
RA Glenn A.E., Gordon A., Gueldener U., Harris D.R., Hollin W., Jaromczyk J.,
RA Johnson R.D., Khan A.K., Leistner E., Leuchtmann A., Li C., Liu J., Liu J.,
RA Liu M., Mace W., Machado C., Nagabhyru P., Pan J., Schmid J., Sugawara K.,
RA Steiner U., Takach J.E., Tanaka E., Webb J.S., Wilson E.V., Wiseman J.L.,
RA Yoshida R., Zeng Z.;
RT "Plant-symbiotic fungi as chemical engineers: Multi-genome analysis of the
RT Clavicipitaceae reveals dynamics of alkaloid loci.";
RL PLoS Genet. 9:E1003323-E1003323(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCE33519.1}.
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DR EMBL; CAGA01000060; CCE33519.1; -; Genomic_DNA.
DR AlphaFoldDB; M1WHY1; -.
DR STRING; 1111077.M1WHY1; -.
DR VEuPathDB; FungiDB:CPUR_07444; -.
DR eggNOG; ENOG502S94X; Eukaryota.
DR HOGENOM; CLU_033263_0_0_1; -.
DR OrthoDB; 2782678at2759; -.
DR PhylomeDB; M1WHY1; -.
DR Proteomes; UP000016801; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR InterPro; IPR005804; FA_desaturase_dom.
DR PANTHER; PTHR36459:SF1; FATTY ACID DESATURASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR36459; ORF; 1.
DR Pfam; PF00487; FA_desaturase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016801};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 126..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 160..380
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
FT REGION 28..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..42
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..61
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 51550 MW; 348591511D7C1B74 CRC64;
MDEQIVFDKG LTKADRVVLQ SLAEDIRTHV APRSKKNSAS HESDVDSGLG SEPSSGDEAS
HAAQQTDDRR IAALKAARNP GSTKFEPTVV VSVDDVSAFL HPLVNQYLLQ PYVRQARKIV
RHETDVVMIT HLILYLTTSV PSALLLFRHF TYTHAILHVV MQGYYVGTYT LMQHQHIHQR
GILAKQFAVL DQLLPYILDP LMGHTWNTYY YHHVKHHHVE GNGPDDLSST IRFQRDSVPD
FLCYVGRFYF LIWFDLPRYF FRKNRPGMAF KMICSELANY AFYYLVSRIA GIKATFFVYI
IPLLIMRVGL MVGNWGQHAF VDQNEPDSDF RSSVTLVDVA SNRFCFNDGY HTSHHLNPLR
HWRDHPISFM EQKHTYAKEG ALVFHNIDYL MITFRLLAKD YDHLAKCLVP IGDQIKLTMD
ERVQLLKKST RKFSEEEIAQ KFKKTQ
//
