ID M1XMY7_NATM8 Unreviewed; 237 AA.
AC M1XMY7;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Cobalt-precorrin-8 methylmutase {ECO:0000313|EMBL:CCQ35257.1};
DE EC=5.4.99.60 {ECO:0000313|EMBL:CCQ35257.1};
GN Name=cbiC {ECO:0000313|EMBL:CCQ35257.1};
GN Synonyms=cobH {ECO:0000313|EMBL:CCQ35257.1};
GN OrderedLocusNames=Nmlp_1045 {ECO:0000313|EMBL:CCQ35257.1};
OS Natronomonas moolapensis (strain DSM 18674 / CECT 7526 / JCM 14361 /
OS 8.8.11).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Natronomonas.
OX NCBI_TaxID=268739 {ECO:0000313|EMBL:CCQ35257.1, ECO:0000313|Proteomes:UP000011867};
RN [1] {ECO:0000313|EMBL:CCQ35257.1, ECO:0000313|Proteomes:UP000011867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18674 / JCM 14361 / 8.8.11
RC {ECO:0000313|Proteomes:UP000011867};
RX PubMed=23516216; DOI=10.1128/genomeA.00095-13;
RA Dyall-Smith M.L., Pfeiffer F., Oberwinkler T., Klee K., Rampp M., Palm P.,
RA Gross K., Schuster S.C., Oesterhelt D.;
RT "Genome of the haloarchaeon Natronomonas moolapensis, a neutrophilic member
RT of a previously haloalkaliphilic genus.";
RL Genome Announc. 1:e0009513-e0009513(2013).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
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DR EMBL; HF582854; CCQ35257.1; -; Genomic_DNA.
DR RefSeq; WP_015408107.1; NC_020388.1.
DR AlphaFoldDB; M1XMY7; -.
DR STRING; 268739.Nmlp_1045; -.
DR GeneID; 14652342; -.
DR KEGG; nmo:Nmlp_1045; -.
DR eggNOG; arCOG02247; Archaea.
DR HOGENOM; CLU_084703_1_0_2; -.
DR OrthoDB; 24491at2157; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000011867; Chromosome.
DR GO; GO:0043778; F:cobalt-precorrin-8 methylmutase activity; IEA:UniProtKB-EC.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:CCQ35257.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011867}.
FT DOMAIN 28..223
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 237 AA; 24990 MW; D61603F14EFC5B52 CRC64;
MTTERADDDG DDFEAYADLG ATTSNAMEIA ETSMDRVHEL VPQETLADRI RAKSVHATGD
SEFQYLMRFT GADESEPVRV GARAVLEERP IVTDITMVKA GITGRGHDCP VRKAIGNGAE
LAAETGMTRT AASVLELDRE GVYDGAIATI GNAPTAALSL ADCIEQGTRP AVVVATPVGF
VKAAESRERI REVCAEHGVP AITNVGRRGG SGLAAGLTNE LVHVASDARE GDVEVKR
//
