ID   M1YZK8_NITG3            Unreviewed;       678 AA.
AC   M1YZK8;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=Histidine kinase domain-containing protein {ECO:0000259|PROSITE:PS50109};
GN   ORFNames=NITGR_500006 {ECO:0000313|EMBL:CCQ90941.1};
OS   Nitrospina gracilis (strain 3/211).
OC   Bacteria; Nitrospinae/Tectomicrobia group; Nitrospinota; Nitrospinia;
OC   Nitrospinales; Nitrospinaceae; Nitrospina.
OX   NCBI_TaxID=1266370 {ECO:0000313|EMBL:CCQ90941.1, ECO:0000313|Proteomes:UP000011704};
RN   [1] {ECO:0000313|EMBL:CCQ90941.1, ECO:0000313|Proteomes:UP000011704}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3/211 {ECO:0000313|EMBL:CCQ90941.1,
RC   ECO:0000313|Proteomes:UP000011704};
RX   PubMed=23439773; DOI=10.3389/fmicb.2013.00027;
RA   Luecker S., Nowka B., Rattei T., Spieck E., and Daims H.;
RT   "The genome of Nitrospina gracilis illuminates the metabolism and evolution
RT   of the major marine nitrite oxidizer.";
RL   Front. Microbiol. 4:27-27(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCQ90941.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CAQJ01000056; CCQ90941.1; -; Genomic_DNA.
DR   AlphaFoldDB; M1YZK8; -.
DR   STRING; 1266370.NITGR_500006; -.
DR   HOGENOM; CLU_405341_0_0_0; -.
DR   InParanoid; M1YZK8; -.
DR   OrthoDB; 9792869at2; -.
DR   Proteomes; UP000011704; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR   Gene3D; 1.20.5.1930; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR   PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR   PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR   Pfam; PF13185; GAF_2; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF07730; HisKA_3; 1.
DR   SMART; SM00065; GAF; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011704};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   TRANSMEM        50..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          483..678
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
FT   COILED          445..483
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   678 AA;  77026 MW;  05E536CEE87BDD76 CRC64;
     MDQRKPFFVQ ISFTEVLQID YNASFAINPT DLPLIGYQKV EPRPEFVKLL WGILAAFLFV
     IDLLLPEGTI DGFFYVILVL AALRIRHKNF LIMATLLATM LNMIGFYLAL DGPNLYQELL
     DRLGSTLTIW VAGWLCLVQQ KSEDHAYQLL QRQGSFVQLH KDIAVASNET RAVEETLQYC
     LRRICHQAGW PVGHLYLVNS PANPNLVSTT TWHLENPEQF QTFRSVSEGT VFDSGIGLPG
     RVLANGKPAW IIDVNKDPNF PRARLSPNIG VKAGFAFPIL IGNEVAGIME FFSPRAEPPN
     DDMLEVMGHI GTLLGRVLER KRAEDEQEQL LHFLKERVNE QTCLYNVANL IANAKTIREV
     FNNLQSYVAS AWQYPEITRV KVVFGEEAFA PPDFRETPWT MSAPLTIHGV QQGSLVVCYL
     EERPDSEEGP FVKEERRLLD GLAYLLSVAA QRKLAEEEIE RSRQQLRNLY NKLETVREEE
     RSRIAREIHD EMAQVLTTMK LEVARLCKKL EISHPDLKEN AETVIELIDQ TIPTVKQLIH
     DLRPPILDHF GLEEAISWQG QEFERLTGIQ FEFDCDSEPE NLDKERSTTL FRIFQETLTN
     VARHSKAENV SVKLNDENGM VSLHVQDDGV GITQDRLKNG HSLGILGMQE RARVWGGSVN
     FVSKPNEGTL VTINISRN
//