ID M1Z7Z3_9FIRM Unreviewed; 555 AA.
AC M1Z7Z3;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit {ECO:0000313|EMBL:SHD77821.1};
GN Name=PorA {ECO:0000313|EMBL:SHD77821.1};
GN ORFNames=CUESP1_2475 {ECO:0000313|EMBL:SHD77821.1};
OS [Clostridium] ultunense Esp.
OC Bacteria; Bacillota; Tissierellia; Tissierellales; Tepidimicrobiaceae;
OC Schnuerera.
OX NCBI_TaxID=1288971 {ECO:0000313|EMBL:SHD77821.1, ECO:0000313|Proteomes:UP000245423};
RN [1] {ECO:0000313|EMBL:SHD77821.1, ECO:0000313|Proteomes:UP000245423}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Clostridium ultunense strain Esp {ECO:0000313|EMBL:SHD77821.1};
RA Manzoor S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LT669839; SHD77821.1; -; Genomic_DNA.
DR AlphaFoldDB; M1Z7Z3; -.
DR HOGENOM; CLU_017038_1_0_9; -.
DR OrthoDB; 9794954at2; -.
DR Proteomes; UP000245423; Chromosome chri.
DR GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR InterPro; IPR022367; 2-oxoacid/accept_OxRdtase_asu.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR NCBIfam; TIGR03710; OAFO_sf; 1.
DR PANTHER; PTHR32154:SF20; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORA; 1.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01558; POR; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Pyruvate {ECO:0000313|EMBL:SHD77821.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000245423}.
FT DOMAIN 11..163
FT /note="Pyruvate/ketoisovalerate oxidoreductase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01558"
FT DOMAIN 191..428
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 454..525
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
SQ SEQUENCE 555 AA; 61845 MW; BD147985132B4AFD CRC64;
MDYTVLVGGE AGQGMDTFAN LLEKILKRAG FHVFSKSDYM SRVRGGHNFI QIRFSNKPIY
AHTEKVDIVF ALNEETVEQH LTRLKENGIV ITDEGIGKDK DLFHLPLLKT AKALRNSRVY
TTIGLGAILK YYGLPLKTGE EVIREGFNEK LYKININALR AGYGMVDSEY SLPTLEDKHI
LINGNQAVGL GAIAAGCKFY CGYPMTPSTG VLNYIAAHAN EMGIAVDQVE DEVAALNMAL
GASYAGVRAM TGSSGGGFAL MVEALSLAGI IEVPVVVINV QRPGPATGFP TRTEQADLRF
MIHAGHGEFP RMVIALRDPE DAFYQTARAF NIAEKYQIPV LLMSDQYLAD STTTREPFDF
SKIKIERRIS GEEGVLDQEY KRYKFTEDGI SPRILPGKIP GQVVLVDSDE HDEWGNITES
DEIRIKMVNK RMKKFEGLKE EVEEPWLLGD EKPENLIISW GSTYGPVREA VEKLLEEGIS
IGALVFGDIW PLPTKKLMEM SKFAKRIIDV EQNATAQLDS LIREELLIKS TDKILKYDGR
PFSGDELYTR LKEVL
//
