ID   M1ZE68_9FIRM            Unreviewed;       450 AA.
AC   M1ZE68;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Uncharacterized transporter HI_0883 {ECO:0000313|EMBL:SHD78056.1};
GN   ORFNames=CUESP1_2719 {ECO:0000313|EMBL:SHD78056.1};
OS   [Clostridium] ultunense Esp.
OC   Bacteria; Bacillota; Tissierellia; Tissierellales; Tepidimicrobiaceae;
OC   Schnuerera.
OX   NCBI_TaxID=1288971 {ECO:0000313|EMBL:SHD78056.1, ECO:0000313|Proteomes:UP000245423};
RN   [1] {ECO:0000313|EMBL:SHD78056.1, ECO:0000313|Proteomes:UP000245423}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Clostridium ultunense strain Esp {ECO:0000313|EMBL:SHD78056.1};
RA   Manzoor S.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LT669839; SHD78056.1; -; Genomic_DNA.
DR   RefSeq; WP_005587180.1; NZ_LT669839.1.
DR   AlphaFoldDB; M1ZE68; -.
DR   HOGENOM; CLU_024867_1_0_9; -.
DR   OrthoDB; 9804874at2; -.
DR   Proteomes; UP000245423; Chromosome chri.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF14; SODIUM_AMINO ACID (ALANINE) SYMPORTER-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245423};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        14..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        70..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        98..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        173..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        212..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        239..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        301..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        341..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        391..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        418..438
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   450 AA;  48383 MW;  624A7218E828BA93 CRC64;
     MNIMEIVNVL NENLWNKVLI FLLLGTGIYY TIRLRFIQVR RFKDINAHVF GNVFKREEKA
     DKDGMSSFQA LATSIAAQVG TGNLAGVATA IASGGPGAIF WMWVSAFFGM GTIFGEAVLA
     QKYVEKIDGE VTGGPAYYLR KGLNSKLLAG FFAITIIIAL GFVGNMVQSN SIAVALTSAF
     SIPNWVGGII AAIFAGLIFA GGMSRIASFT ELIVPFMAIL YIVGSFLIIV LNYTQIIPAF
     KIIISSAFSA KAAVGGAIGV TVKEAVRYGI ARGLFSNEAG MGSTPHAHAV AKVDHPAEQG
     LVAIFGVIFD TLVICTITAL INITTGAYTL GLTGIEMTQK AFGIGLGNFG TIFVAISLFF
     FAFSTIIGWY YFGESNIKYL FGAKAIWPYR IIVLLFIVLG SILSVDAVWQ IADLFNGLMV
     LPNVIGLLIL SPQAISILRD YERNFLDSVK
//