ID M2M3S8_BAUPA Unreviewed; 333 AA.
AC M2M3S8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=ER membrane protein complex subunit 2 {ECO:0000256|RuleBase:RU367091};
GN ORFNames=BAUCODRAFT_318893 {ECO:0000313|EMBL:EMC91226.1};
OS Baudoinia panamericana (strain UAMH 10762) (Angels' share fungus)
OS (Baudoinia compniacensis (strain UAMH 10762)).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Teratosphaeriaceae; Baudoinia.
OX NCBI_TaxID=717646 {ECO:0000313|EMBL:EMC91226.1, ECO:0000313|Proteomes:UP000011761};
RN [1] {ECO:0000313|EMBL:EMC91226.1, ECO:0000313|Proteomes:UP000011761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 10762 {ECO:0000313|EMBL:EMC91226.1,
RC ECO:0000313|Proteomes:UP000011761};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
CC -!- FUNCTION: Part of the endoplasmic reticulum membrane protein complex
CC (EMC) that enables the energy-independent insertion into endoplasmic
CC reticulum membranes of newly synthesized membrane proteins.
CC {ECO:0000256|RuleBase:RU367091}.
CC -!- SUBUNIT: Component of the ER membrane protein complex (EMC).
CC {ECO:0000256|RuleBase:RU367091}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|RuleBase:RU367091}; Peripheral membrane protein
CC {ECO:0000256|RuleBase:RU367091}; Cytoplasmic side
CC {ECO:0000256|RuleBase:RU367091}.
CC -!- SIMILARITY: Belongs to the EMC2 family.
CC {ECO:0000256|RuleBase:RU367091}.
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DR EMBL; KB445564; EMC91226.1; -; Genomic_DNA.
DR RefSeq; XP_007681648.1; XM_007683458.1.
DR AlphaFoldDB; M2M3S8; -.
DR STRING; 717646.M2M3S8; -.
DR GeneID; 19111622; -.
DR KEGG; bcom:BAUCODRAFT_318893; -.
DR eggNOG; KOG3060; Eukaryota.
DR HOGENOM; CLU_052388_0_0_1; -.
DR OMA; LMEMLFY; -.
DR OrthoDB; 1425339at2759; -.
DR Proteomes; UP000011761; Unassembled WGS sequence.
DR GO; GO:0072546; C:EMC complex; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR039856; EMC2-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12760:SF0; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 2; 1.
DR PANTHER; PTHR12760; TETRATRICOPEPTIDE REPEAT PROTEIN; 1.
DR Pfam; PF14559; TPR_19; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|RuleBase:RU367091};
KW Membrane {ECO:0000256|RuleBase:RU367091};
KW Reference proteome {ECO:0000313|Proteomes:UP000011761};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 161..194
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 333 AA; 37150 MW; 3630751CEBC663B8 CRC64;
MSDPLLEAPT QTNPSHTLAL SQKARPYLDS RPWYFTTLPY PLSLFLAPES QERWAASQNL
FLASLIADDL PVAYAYLEDI TERFGKLNER VMALQGLYQE ASAKDTKALE DVVKNYDELL
KTDPTLMAIR KRRVAVLKGV GRIADAVGDL VLMLDASPTD AEAWAELADC YVSQGAYEQA
VWCLEEVLLV MPNAWNMHAR LAEVQYIQSQ KMSEGSGEQL KTLSESMRRF CRSIELCDDY
LRGYYGLKIT TARLLAILEK VKKPPTASSD LVAGDLAPPK VATVYKLNEL ATAKLAEIVR
RSSAEEKGWD GYSGAELKAA KAMIEKDTQK IER
//
