ID   M2MJT8_BAUPA            Unreviewed;       636 AA.
AC   M2MJT8;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   13-SEP-2023, entry version 45.
DE   RecName: Full=Alpha-actinin-2 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BAUCODRAFT_69320 {ECO:0000313|EMBL:EMC96956.1};
OS   Baudoinia panamericana (strain UAMH 10762) (Angels' share fungus)
OS   (Baudoinia compniacensis (strain UAMH 10762)).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Mycosphaerellales; Teratosphaeriaceae; Baudoinia.
OX   NCBI_TaxID=717646 {ECO:0000313|EMBL:EMC96956.1, ECO:0000313|Proteomes:UP000011761};
RN   [1] {ECO:0000313|EMBL:EMC96956.1, ECO:0000313|Proteomes:UP000011761}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 10762 {ECO:0000313|EMBL:EMC96956.1,
RC   ECO:0000313|Proteomes:UP000011761};
RX   PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA   Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA   Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA   LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA   Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA   Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA   Grigoriev I.V.;
RT   "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT   genomes of eighteen Dothideomycetes fungi.";
RL   PLoS Pathog. 8:E1003037-E1003037(2012).
CC   -!- SIMILARITY: Belongs to the alpha-actinin family.
CC       {ECO:0000256|ARBA:ARBA00010255}.
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DR   EMBL; KB445554; EMC96956.1; -; Genomic_DNA.
DR   RefSeq; XP_007675511.1; XM_007677321.1.
DR   AlphaFoldDB; M2MJT8; -.
DR   STRING; 717646.M2MJT8; -.
DR   GeneID; 19116515; -.
DR   KEGG; bcom:BAUCODRAFT_69320; -.
DR   eggNOG; KOG0035; Eukaryota.
DR   HOGENOM; CLU_005217_0_2_1; -.
DR   OMA; CYEGVEV; -.
DR   OrthoDB; 2872403at2759; -.
DR   Proteomes; UP000011761; Unassembled WGS sequence.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR   CDD; cd21215; CH_SpAIN1-like_rpt1; 1.
DR   CDD; cd21291; CH_SpAIN1-like_rpt2; 1.
DR   CDD; cd00051; EFh; 1.
DR   Gene3D; 1.20.58.60; -; 2.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR   Gene3D; 1.10.238.10; EF-hand; 2.
DR   InterPro; IPR001589; Actinin_actin-bd_CS.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR014837; EF-hand_Ca_insen.
DR   InterPro; IPR002048; EF_hand_dom.
DR   PANTHER; PTHR11915:SF435; SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5; 1.
DR   PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR   Pfam; PF00307; CH; 2.
DR   Pfam; PF08726; EFhand_Ca_insen; 1.
DR   SMART; SM00033; CH; 2.
DR   SMART; SM01184; efhand_Ca_insen; 1.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   SUPFAM; SSF47473; EF-hand; 1.
DR   SUPFAM; SSF46966; Spectrin repeat; 2.
DR   PROSITE; PS00019; ACTININ_1; 1.
DR   PROSITE; PS00020; ACTININ_2; 1.
DR   PROSITE; PS50021; CH; 2.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011761};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          11..116
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          125..231
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          485..520
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
SQ   SEQUENCE   636 AA;  73274 MW;  D947EAA03C250593 CRC64;
     MAVLLDQAWV KVQAKTFTKW LNNKLTARNV QIDDLVKDLS DGIILIHLLE ILSNESLGRY
     AARPKLRVQR FENVNIALEF IKSRKIQLTN IGAEDIVDGN RKIILGLIWT LILRFTISDI
     NDQGLSAREG LLLWCQRKTA CYEDVHIQDF SGSWNNGLGF CALLDIHRPD LIDYDKLDKS
     DHRGNMQLAF DIASNEIGIP DLLDVEDVCD VAKPDERSLM TYIAYWFHAF SQMERVENAG
     RRVEKFVSNM NGAWEMQNNF ERRMRALLEQ IAEQVKSWST ARFDGTYTDA KEQSKDFTKY
     KQKEKRKWVA EKSDLAGLLG NIKTKLSTYR LRPYEPPPEL RLEALDRAWA ELVEAEHQRS
     QVINNTIRDI KNNLRRTFAD KANDFALALQ TISMSISGLE GDVEDQLDHS NQIALNLPPL
     DQYLDLIARL DTQCQEANIE ENDFTTYTYD ELAYELSLVR SSVQKKLAFL ENQMVARNMT
     NLTPIQLEEF ESVFRHFDRD LSNSLQELEF SAALASLGLV YDEQEMHERF VEVAGRGGSV
     SFEQFIRFMV AVTEDQNTAE QVFESFREVA DGKPYVTELD LTHSLIPEDV VQMLVESMPP
     HRGPDLQEDR EVPKYDYVRF MEDFVGSVPR SNGVRH
//