ID   M2MM50_BAUPA            Unreviewed;       823 AA.
AC   M2MM50;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   03-MAY-2023, entry version 37.
DE   RecName: Full=Probable vacuolar protein sorting-associated protein 16 homolog {ECO:0000256|PIRNR:PIRNR007949};
GN   ORFNames=BAUCODRAFT_66530 {ECO:0000313|EMBL:EMC97761.1};
OS   Baudoinia panamericana (strain UAMH 10762) (Angels' share fungus)
OS   (Baudoinia compniacensis (strain UAMH 10762)).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Mycosphaerellales; Teratosphaeriaceae; Baudoinia.
OX   NCBI_TaxID=717646 {ECO:0000313|EMBL:EMC97761.1, ECO:0000313|Proteomes:UP000011761};
RN   [1] {ECO:0000313|EMBL:EMC97761.1, ECO:0000313|Proteomes:UP000011761}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 10762 {ECO:0000313|EMBL:EMC97761.1,
RC   ECO:0000313|Proteomes:UP000011761};
RX   PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA   Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA   Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA   LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA   Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA   Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA   Grigoriev I.V.;
RT   "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT   genomes of eighteen Dothideomycetes fungi.";
RL   PLoS Pathog. 8:E1003037-E1003037(2012).
CC   -!- FUNCTION: Essential for vacuolar protein sorting. Required for vacuole
CC       biogenesis, stability and to maintain vacuole morphology.
CC       {ECO:0000256|PIRNR:PIRNR007949}.
CC   -!- SIMILARITY: Belongs to the VPS16 family.
CC       {ECO:0000256|ARBA:ARBA00009250, ECO:0000256|PIRNR:PIRNR007949}.
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DR   EMBL; KB445553; EMC97761.1; -; Genomic_DNA.
DR   RefSeq; XP_007674604.1; XM_007676414.1.
DR   AlphaFoldDB; M2MM50; -.
DR   STRING; 717646.M2MM50; -.
DR   GeneID; 19116289; -.
DR   KEGG; bcom:BAUCODRAFT_66530; -.
DR   eggNOG; KOG2280; Eukaryota.
DR   HOGENOM; CLU_008909_1_0_1; -.
DR   OMA; HMTIRDH; -.
DR   OrthoDB; 1110811at2759; -.
DR   Proteomes; UP000011761; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0007033; P:vacuole organization; IEA:InterPro.
DR   Gene3D; 1.10.150.780; Vps16, C-terminal region; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR016534; VPS16.
DR   InterPro; IPR006925; Vps16_C.
DR   InterPro; IPR038132; Vps16_C_sf.
DR   InterPro; IPR006926; Vps16_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR12811; VACUOLAR PROTEIN SORTING VPS16; 1.
DR   PANTHER; PTHR12811:SF0; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG; 1.
DR   Pfam; PF04840; Vps16_C; 1.
DR   Pfam; PF04841; Vps16_N; 1.
DR   PIRSF; PIRSF007949; VPS16; 1.
DR   SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE   3: Inferred from homology;
KW   Protein transport {ECO:0000256|PIRNR:PIRNR007949};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011761};
KW   Transport {ECO:0000256|PIRNR:PIRNR007949}.
FT   DOMAIN          7..408
FT                   /note="Vps16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04841"
FT   DOMAIN          501..808
FT                   /note="Vps16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04840"
SQ   SEQUENCE   823 AA;  92622 MW;  FE5341C8B1BDB6FA CRC64;
     MSGARAGWEP VGDRFYRKTQ LYTSVFDQDL ELENYVVTGA PYSGAVALYR DASKIFSLRG
     AQSAKSSIDI YSCAGKLIRQ IPWERQTVKA VGWSEDERLL VITNDGTVRS YADLHGDFTP
     FNIGHGAEEH GVKGCKFWSN GFVALLGNNR LVAVTRYEEP RPQLLASTPS GEVMSWTVIP
     PEYTSSRAVE VLLAINKTVY VVDPAECEDR GLEAGPFRHI GVSPNGKFIA LYTDDSKVWV
     ISSDFQDRYS EYESKVKTIP KDLQWCGNNA VVLAWEDELH LVGPNGAASK FYYDSIMHLL
     PDIDGIRVLT SDICEFLQKV PDPTEEVFRL GSTSPASVLL DALHHLEDKS PKADDNIQLI
     RESLDEAVDV CVRAAGQEYS IHWQKQLLKA ASFGKSVLDL YNSDDFVDMT ETLRVLNAVR
     FFEVALPLSY EQYLRLTPER LVQRLVNRQM YLLALKVSEY LHLPVDRIYV HWARQKVRSS
     RTDEDSICAE IVQKLNGKRG ISFEEVARAA YDEGRGKLAT DLLEHEPRAG KQVPLLLNVG
     EDTIALDKAI ESGDTDLVFY VLLNLRKKMP LSSFFRTINS RPTATAIVES SAVDQDEELL
     KDLYYQDDRR IEGSNLLVSE ALAASDTAPA TDKLKMAAKL VRDSKEYAVQ VTAIEDAQKL
     LRLQETFAKE LNERFVGLSV NETLSKLIRT GNMKRATKVQ TEFKVTEKVY WWIRLRALVS
     NRDWRELEEM SKARKSPIGW EPFYNEILAA GNTKVAALFI PKCASLTLSE RIEMWLKCGL
     VAKAGEEALK AKDRNALEDL RKQATGNAAV EIERMIGLLQ KGR
//