ID M2NBE8_BAUPA Unreviewed; 830 AA.
AC M2NBE8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Mitochondrial escape protein 2 {ECO:0000256|ARBA:ARBA00020222, ECO:0000256|RuleBase:RU367108};
GN ORFNames=BAUCODRAFT_70204 {ECO:0000313|EMBL:EMC96215.1};
OS Baudoinia panamericana (strain UAMH 10762) (Angels' share fungus)
OS (Baudoinia compniacensis (strain UAMH 10762)).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Teratosphaeriaceae; Baudoinia.
OX NCBI_TaxID=717646 {ECO:0000313|EMBL:EMC96215.1, ECO:0000313|Proteomes:UP000011761};
RN [1] {ECO:0000313|EMBL:EMC96215.1, ECO:0000313|Proteomes:UP000011761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 10762 {ECO:0000313|EMBL:EMC96215.1,
RC ECO:0000313|Proteomes:UP000011761};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
CC -!- FUNCTION: Plays a role in maintaining the mitochondrial genome and in
CC controlling the mtDNA escape. Involved in the regulation of mtDNA
CC nucleotide structure and number. May have a dispensable role in early
CC maturation of pre-rRNA. {ECO:0000256|ARBA:ARBA00025276,
CC ECO:0000256|RuleBase:RU367108}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004434,
CC ECO:0000256|RuleBase:RU367108}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004434, ECO:0000256|RuleBase:RU367108}.
CC -!- SIMILARITY: Belongs to the YME2 family. {ECO:0000256|ARBA:ARBA00010320,
CC ECO:0000256|RuleBase:RU367108}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB445555; EMC96215.1; -; Genomic_DNA.
DR RefSeq; XP_007676297.1; XM_007678107.1.
DR AlphaFoldDB; M2NBE8; -.
DR GeneID; 19116574; -.
DR KEGG; bcom:BAUCODRAFT_70204; -.
DR eggNOG; ENOG502QS0P; Eukaryota.
DR HOGENOM; CLU_007861_0_0_1; -.
DR OMA; WTPEQAW; -.
DR OrthoDB; 1384689at2759; -.
DR Proteomes; UP000011761; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000002; P:mitochondrial genome maintenance; IEA:UniProtKB-UniRule.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-UniRule.
DR CDD; cd12433; RRM_Yme2p_like; 1.
DR InterPro; IPR018850; Mt_escape_2_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR039627; Yme2_C.
DR InterPro; IPR034260; Yme2_RRM.
DR PANTHER; PTHR32198; MITOCHONDRIAL ESCAPE PROTEIN 2; 1.
DR PANTHER; PTHR32198:SF2; MITOCHONDRIAL ESCAPE PROTEIN 2; 1.
DR Pfam; PF10443; RNA12; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW ECO:0000256|RuleBase:RU367108};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792,
KW ECO:0000256|RuleBase:RU367108};
KW mRNA processing {ECO:0000256|RuleBase:RU367108};
KW Reference proteome {ECO:0000313|Proteomes:UP000011761};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176,
KW ECO:0000256|RuleBase:RU367108};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 165..257
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 830 AA; 93189 MW; 3D4B9C2A9A31FE4C CRC64;
MLQRRLLLQR PCLRSLPVPR LHQRSRLRQV RHATAEAGEN ESGHIATTPN EGILFFNNLL
PLSIPFMRLL PFVLRSNKSS ILQDADKWMR VGALVVEILP RLREAGAFLK FQHQEQDDPA
TVAEAVRQYL RAHPTRPWWN PFDPVRAGLV VGKPWVEDLF RLPSKRLKVE FLPTAPGAEV
AELNQEQLYA FFRPYGKLAD IVVQPSDSKI MPRFAYLDYS QVGKAIMAKN CLHGFTVPEP
QGGGKLGTIF RITYEKRRQG GWIWDWITNH PRIVFPIVVA LVAGISVTIF DPIRTLSIKA
HITHSFHIED NVIFRWFKTQ SEDLLKKVRE LRHGVDESEA GMQVVWDDRK ADIEQIQSWL
METADTFIVV QGPRGSGKRE LVIDHALQRK QAAHRVLVVD CKPVQEARGD GPTIAAAASQ
VGYWPVFSWM NSLNGMLDLA AQGLTGVKAG FSETLDTQLS KIWNSTAVAL KSIALEGRKK
DDKDANLSDD EYLEAHPERR PVVVIDNFLH KSSDAGAGLV YDKLAEWAAR LTTTNVAHVI
FLTNDLSYSK SLGRALPDRV FRQITLRDCS LETAKRYVIH HLDFDKAEDR PTQDESDEAR
KLTPSQKRKD LAELDHVIPL LGGRLTDLEF LARRIKAGET PTKAVHEIIE QSASEILKMY
LLSGGGSGSS GETREWSIPQ AWTLIRSLAA SETLRYNEML LLDAYKSAGD RALAALEQAE
LITVQSLNGR PCSIGPGKPV YRPAFQRLVD DKVLAAKMDL AVLGESIGNE NKSIDGYERE
LHLLGELPKQ PGELRGRVQW LLGKIEACQG KIEGYEKESA GLKKILVSEY
//
