ID M2P7S7_9FIRM Unreviewed; 312 AA.
AC M2P7S7;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000256|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000256|HAMAP-Rule:MF_01420};
GN ORFNames=HMPREF9943_01298 {ECO:0000313|EMBL:EMD16372.1};
OS Eggerthia catenaformis OT 569 = DSM 20559.
OC Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC Coprobacillaceae; Eggerthia.
OX NCBI_TaxID=999415 {ECO:0000313|EMBL:EMD16372.1, ECO:0000313|Proteomes:UP000011758};
RN [1] {ECO:0000313|EMBL:EMD16372.1, ECO:0000313|Proteomes:UP000011758}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OT 569 {ECO:0000313|EMBL:EMD16372.1,
RC ECO:0000313|Proteomes:UP000011758};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Izard J., Blanton J.M.,
RA Mathney J., Dewhirst F.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA Haas B., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.,
RA Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lactobacillus catenaformis F0143.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000256|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000256|HAMAP-
CC Rule:MF_01420}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMD16372.1}.
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DR EMBL; AGEJ01000021; EMD16372.1; -; Genomic_DNA.
DR RefSeq; WP_004803249.1; NZ_KB446648.1.
DR AlphaFoldDB; M2P7S7; -.
DR STRING; 999415.HMPREF9943_01298; -.
DR PATRIC; fig|999415.3.peg.1317; -.
DR eggNOG; COG1481; Bacteria.
DR OrthoDB; 401278at2; -.
DR Proteomes; UP000011758; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR NCBIfam; TIGR00647; DNA_bind_WhiA; 1.
DR PANTHER; PTHR37307; CELL DIVISION PROTEIN WHIA-RELATED; 1.
DR PANTHER; PTHR37307:SF1; CELL DIVISION PROTEIN WHIA-RELATED; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR Pfam; PF10298; WhiA_N; 1.
DR SUPFAM; SSF55608; Homing endonucleases; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|HAMAP-
KW Rule:MF_01420};
KW Cell division {ECO:0000256|ARBA:ARBA00022618, ECO:0000256|HAMAP-
KW Rule:MF_01420};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_01420}; Reference proteome {ECO:0000313|Proteomes:UP000011758}.
FT DOMAIN 19..102
FT /note="Sporulation transcription regulator WhiA N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10298"
FT DOMAIN 123..214
FT /note="WhiA LAGLIDADG-like"
FT /evidence="ECO:0000259|Pfam:PF14527"
FT DOMAIN 218..303
FT /note="Sporulation regulator WhiA C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02650"
SQ SEQUENCE 312 AA; 35397 MW; E1C4904DAE8F9370 CRC64;
MLSFSRKVKE EIVFNDFDRS CSKALLSALI KVTGTLHIGN GMSLTIRSEN AKIASKTHKL
LKELYNPQLE FMVSRKMKLH KNNIYILKVS KAKEILDDLQ LMDGLGVSKI PSDTLLKDTM
TKRAYLAGIF LAGGSVNNPD TSNYHLEMSV LSSTHARFIQ ELTNEYDLNA KIIKRRNKYV
VYLKSAEKIG DFLRAIGAAQ SVLDFEMTRI DRSMANTVNR WNNCDIANEM KAMSAAEKQI
EDIAYVVEKA GLEILDSKTQ EAAKIRLENP ELSLNELTEI YMLKTGQSIS KSGLHHRFKK
IKEEADRLRK ME
//
