ID M2P801_CERS8 Unreviewed; 1383 AA.
AC M2P801;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
GN ORFNames=CERSUDRAFT_127336 {ECO:0000313|EMBL:EMD31449.1};
OS Ceriporiopsis subvermispora (strain B) (White-rot fungus) (Gelatoporia
OS subvermispora).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Gelatoporiaceae; Gelatoporia.
OX NCBI_TaxID=914234 {ECO:0000313|EMBL:EMD31449.1, ECO:0000313|Proteomes:UP000016930};
RN [1] {ECO:0000313|EMBL:EMD31449.1, ECO:0000313|Proteomes:UP000016930}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B {ECO:0000313|EMBL:EMD31449.1,
RC ECO:0000313|Proteomes:UP000016930};
RX PubMed=22434909; DOI=10.1073/pnas.1119912109;
RA Fernandez-Fueyo E., Ruiz-Duenas F.J., Ferreira P., Floudas D.,
RA Hibbett D.S., Canessa P., Larrondo L.F., James T.Y., Seelenfreund D.,
RA Lobos S., Polanco R., Tello M., Honda Y., Watanabe T., Watanabe T.,
RA Ryu J.S., Kubicek C.P., Schmoll M., Gaskell J., Hammel K.E., St John F.J.,
RA Vanden Wymelenberg A., Sabat G., Splinter BonDurant S., Syed K.,
RA Yadav J.S., Doddapaneni H., Subramanian V., Lavin J.L., Oguiza J.A.,
RA Perez G., Pisabarro A.G., Ramirez L., Santoyo F., Master E., Coutinho P.M.,
RA Henrissat B., Lombard V., Magnuson J.K., Kuees U., Hori C., Igarashi K.,
RA Samejima M., Held B.W., Barry K.W., LaButti K.M., Lapidus A.,
RA Lindquist E.A., Lucas S.M., Riley R., Salamov A.A., Hoffmeister D.,
RA Schwenk D., Hadar Y., Yarden O., de Vries R.P., Wiebenga A., Stenlid J.,
RA Eastwood D., Grigoriev I.V., Berka R.M., Blanchette R.A., Kersten P.,
RA Martinez A.T., Vicuna R., Cullen D.;
RT "Comparative genomics of Ceriporiopsis subvermispora and Phanerochaete
RT chrysosporium provide insight into selective ligninolysis.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:5458-5463(2012).
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DR EMBL; KB445818; EMD31449.1; -; Genomic_DNA.
DR STRING; 914234.M2P801; -.
DR HOGENOM; CLU_000288_6_3_1; -.
DR OrthoDB; 1659672at2759; -.
DR Proteomes; UP000016930; Unassembled WGS sequence.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR CDD; cd21037; MLKL_NTD; 1.
DR CDD; cd00200; WD40; 2.
DR Gene3D; 1.20.930.20; Adaptor protein Cbl, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 6.
DR InterPro; IPR036537; Adaptor_Cbl_N_dom_sf.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011044; Quino_amine_DH_bsu.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22847:SF748; TRANSCRIPTIONAL REPRESSOR TUP11; 1.
DR PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF00400; WD40; 12.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 12.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF50969; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR PROSITE; PS50837; NACHT; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 10.
DR PROSITE; PS50082; WD_REPEATS_2; 12.
DR PROSITE; PS50294; WD_REPEATS_REGION; 12.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000016930};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 293..437
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT REPEAT 833..874
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 876..917
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 919..960
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 962..1003
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1005..1046
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1048..1089
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1091..1123
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1134..1175
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1177..1218
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1220..1261
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1263..1304
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1306..1347
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 18..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 76..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 142..200
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 23..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1383 AA; 151598 MW; 70EA18ED856C4C48 CRC64;
MTTSPWRRMK HAISDVLQGP WRRGNADTTQ AHGTAMNSSI HPSTSAQQST AVSVAFPDHA
AGGSGHPSIR TESLVAPSAD AASGSVHSSL DTPSDEMNTS PRGTGWMMLK VLQVVRDGSD
LFILLRTALV GVVEVMDEVD NVGEAQDEFE RIAQDIDQLL QALSPYGMEQ HASPLVRRRL
KRIEEVLDRI RQEIENKARR NGMRRVFESW TDVREVESIF RELAAMIDDF QLECNLHTER
MTEDLEMSRL KAQLQHIPDA GIDAQSGAEC MQGTREALLG DLKAWSGDSA APPIFWLNGM
AGTGKSAIAR SLCLILRRAG VFGGSFFCSR GTNRDDIKRI IPTLTVSLAC QFPAYKRALS
EALRKHPDAG HDRVEVQVER LLRGPLREAF GDVLPTLVLV IDALDECADQ KATSTVLTHL
LQVSPHMPIK FFVTSRPEQH IRAQFERGDL RIQRILRLHD IETSIVETDL ALYIRHRLHE
IRRSMAASEP SYSFPPQWPT DADIVTLACH AGKLFIYAFT ATEYIQTVDP VGRLCRCIGL
EITTGKPFYG PLDDVYTFIL DKALDPKHYE AEELHTIRRI LAAILTVREH LSLDILANLI
GIPAQRIRVM LQALHAVVDV PPLDDVGVIS TFHASFGDFM TTPERAGQFL IDRQTGHRDL
ADCCIRIMDS ELLHFNVNEC TTSYLPNDKQ LCAALPKQLT YGCSYWSYHI VALEDASSQL
QQLDFILSRK LLLWLEVIST LRQPNRASIM IMQVLTAHQS HMADDLSQFL RDANIFVVSC
QDAIERSAPH MYLSALPSAH TSSRIADAFW PGFINVPVIM TMGISRRRII LQHIDNASPV
MAVTSSPDGA CIVSGSYDNT IRIWSVTTGR AMLKPLEGHS GWVKSVASSP DGTRIVSGSA
DNTIRIWDAS TGQALLEPLK GHTYGVTYVV FSPDGTLIVS GSGDKTIRIW DANTGQALLK
PLEGHTCGVC SIAFSPDGSR IVSGSYDKTI RIWDANTGQA LLEPLKGHTS HVNSVAFSPD
GTRIVSGSYD KTIRVWDAHT GHALLKPLEA HTNDVTSVAF SPDGSHIVSG SRDKTIRIWD
MSTGQVLCDA LEGHTCGVTS VIFSPNGTHI MSGSGDKTIC IWDATMGWAL RELLERHSGW
VKSVALSLDG TRIVSGSADN SMCIWDASTG QALLEPLEGH TSHVNSIAFS PDGTRIVSGS
YDKTIRIWDT NTGQVLLEPL EGHANGVSSV AFSPDGTRIV SGSYDKTICT WDVSTGQALL
QLLQGHTESV SSVAFSPDGT RIVSGSHDNT VRIWDASTGQ ALLEPIQGHT NWVSSVAFSP
DGTRIVSGSY DKIIRTWDAS TGQALLEPLK GPTDIVSSIT FSPDGNPHCV RLTRWGNLRV
QGD
//
