ID   M2Q1U8_9FIRM            Unreviewed;       469 AA.
AC   M2Q1U8;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   RecName: Full=M18 family aminopeptidase {ECO:0000256|RuleBase:RU004387};
DE            EC=3.4.11.- {ECO:0000256|RuleBase:RU004387};
GN   ORFNames=HMPREF9943_01664 {ECO:0000313|EMBL:EMD16261.1};
OS   Eggerthia catenaformis OT 569 = DSM 20559.
OC   Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC   Coprobacillaceae; Eggerthia.
OX   NCBI_TaxID=999415 {ECO:0000313|EMBL:EMD16261.1, ECO:0000313|Proteomes:UP000011758};
RN   [1] {ECO:0000313|EMBL:EMD16261.1, ECO:0000313|Proteomes:UP000011758}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OT 569 {ECO:0000313|EMBL:EMD16261.1,
RC   ECO:0000313|Proteomes:UP000011758};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Izard J., Blanton J.M.,
RA   Mathney J., Dewhirst F.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA   Haas B., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.,
RA   Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA   Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA   Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lactobacillus catenaformis F0143.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU004387};
CC   -!- SIMILARITY: Belongs to the peptidase M18 family.
CC       {ECO:0000256|ARBA:ARBA00008290, ECO:0000256|RuleBase:RU004386}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMD16261.1}.
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DR   EMBL; AGEJ01000024; EMD16261.1; -; Genomic_DNA.
DR   AlphaFoldDB; M2Q1U8; -.
DR   PATRIC; fig|999415.3.peg.1691; -.
DR   eggNOG; COG1362; Bacteria.
DR   BioCyc; ECAT999415-HMP:GTTI-1725-MONOMER; -.
DR   Proteomes; UP000011758; Unassembled WGS sequence.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.250.10; Aminopeptidase i, Domain 2; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR001948; Peptidase_M18.
DR   InterPro; IPR023358; Peptidase_M18_dom2.
DR   PANTHER; PTHR28570; ASPARTYL AMINOPEPTIDASE; 1.
DR   PANTHER; PTHR28570:SF2; M18 FAMILY AMINOPEPTIDASE 1-RELATED; 1.
DR   Pfam; PF02127; Peptidase_M18; 1.
DR   PRINTS; PR00932; AMINO1PTASE.
DR   SUPFAM; SSF101821; Aminopeptidase/glucanase lid domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW   ECO:0000256|RuleBase:RU004386};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU004386};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU004386};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW   ECO:0000256|RuleBase:RU004386};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU004386};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011758};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004386}.
SQ   SEQUENCE   469 AA;  52113 MW;  D0A1D51570CDB665 CRC64;
     MIDMKGIVKM ERKTLWENYN DADIKEMNKI SERYKECLDL GKTERECASL IIKMAEENGY
     INLDEAIKEN KRLSAGDKIY ACYNGKTVAL YHLGEDDIEK GMNILGAHID SPRIDVKQNP
     LYEKEGFAYL DTHYYGGIKK YQWVTIPLSM HGVFVKKDGT VINISIGEED NDPVFTITDL
     LIHLSASQLQ KKASEVIEGE NLDLLVGSIL LKDEEKDPIK ANILKLLKEK YDIEEDDFLS
     AELELVPASK ARDLGFDKSM ILGYGQDDRI CAFTSLFAML ESNNLKRTGC TLLVDKEEIG
     SVGASGMHSR FFENTTAEIL NLMGYTKDIS VRRCLAHSTM LSSDVSAGYD PLYANAFEIK
     NAAFLGKGLV FNKFTGARGK SGSNDANAEY MAKVRNVMDS HKIAFQTAEL GKVDIGGGGT
     IAYITANYGM EVIDAGLAVL CMHSPCEVSS KADIYEAVKG YKAFLKDMY
//