ID M2Q2H2_9FIRM Unreviewed; 296 AA.
AC M2Q2H2;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Excisionase family DNA binding domain-containing protein {ECO:0000313|EMBL:EMD17105.1};
GN ORFNames=HMPREF9943_00668 {ECO:0000313|EMBL:EMD17105.1};
OS Eggerthia catenaformis OT 569 = DSM 20559.
OC Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC Coprobacillaceae; Eggerthia.
OX NCBI_TaxID=999415 {ECO:0000313|EMBL:EMD17105.1, ECO:0000313|Proteomes:UP000011758};
RN [1] {ECO:0000313|EMBL:EMD17105.1, ECO:0000313|Proteomes:UP000011758}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OT 569 {ECO:0000313|EMBL:EMD17105.1,
RC ECO:0000313|Proteomes:UP000011758};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Izard J., Blanton J.M.,
RA Mathney J., Dewhirst F.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA Haas B., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.,
RA Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lactobacillus catenaformis F0143.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMD17105.1}.
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DR EMBL; AGEJ01000011; EMD17105.1; -; Genomic_DNA.
DR RefSeq; WP_004802033.1; NZ_KB446647.1.
DR AlphaFoldDB; M2Q2H2; -.
DR STRING; 999415.HMPREF9943_00668; -.
DR PATRIC; fig|999415.3.peg.667; -.
DR eggNOG; COG3177; Bacteria.
DR OrthoDB; 9813719at2; -.
DR BioCyc; ECAT999415-HMP:GTTI-689-MONOMER; -.
DR Proteomes; UP000011758; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3290.10; Fido-like domain; 1.
DR InterPro; IPR003812; Fido.
DR InterPro; IPR036597; Fido-like_dom_sf.
DR InterPro; IPR040198; Fido_containing.
DR InterPro; IPR041657; HTH_17.
DR PANTHER; PTHR13504; FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145; 1.
DR PANTHER; PTHR13504:SF34; PROTEIN ADENYLYLTRANSFERASE FICD; 1.
DR Pfam; PF02661; Fic; 1.
DR Pfam; PF12728; HTH_17; 1.
DR SUPFAM; SSF140931; Fic-like; 1.
DR PROSITE; PS51459; FIDO; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR640198-2};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR640198-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000011758}.
FT DOMAIN 148..286
FT /note="Fido"
FT /evidence="ECO:0000259|PROSITE:PS51459"
FT ACT_SITE 224
FT /evidence="ECO:0000256|PIRSR:PIRSR640198-1"
FT BINDING 228..235
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR640198-2"
FT BINDING 260..261
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR640198-2"
FT SITE 99
FT /note="Important for autoinhibition of adenylyltransferase
FT activity"
FT /evidence="ECO:0000256|PIRSR:PIRSR640198-3"
SQ SEQUENCE 296 AA; 34659 MW; 0EBED7833A7DCE3B CRC64;
MYITVKQAAE KWGISDRRVR ILCSEGKIPG VYQEGRVWKI PYDAIKPTDG RYKIKESLIP
ILEDKLEILK KRRPLTEGEL ERLNEEFLTE YTYNSNAIEG NTLTLRETDM VLRGLTIGQK
SLKEHLEVIG HKEAFDYVRQ LVSENAQISE KVIKDIHYLV LADKKKDRGI YRRVPVRIMG
AAHEPVQPYL IIPKMEELLE QYKNSEENIM TKLARFHIEF EGIHPFIDGN GRTGRLLVNL
ELMKAGYPPI DIKFTDRLKY YEAFDEYYVK HNISAMADMF ARYLNQRLDL YLSILD
//
