ID M2QZB2_COCSN Unreviewed; 869 AA.
AC M2QZB2;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744};
GN ORFNames=COCSADRAFT_40034 {ECO:0000313|EMBL:EMD60394.1};
OS Cochliobolus sativus (strain ND90Pr / ATCC 201652) (Common root rot and
OS spot blotch fungus) (Bipolaris sorokiniana).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX NCBI_TaxID=665912 {ECO:0000313|EMBL:EMD60394.1, ECO:0000313|Proteomes:UP000016934};
RN [1] {ECO:0000313|EMBL:EMD60394.1, ECO:0000313|Proteomes:UP000016934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ND90Pr / ATCC 201652 {ECO:0000313|Proteomes:UP000016934};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
RN [2] {ECO:0000313|Proteomes:UP000016934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ND90Pr / ATCC 201652 {ECO:0000313|Proteomes:UP000016934};
RX PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT "Comparative genome structure, secondary metabolite, and effector coding
RT capacity across Cochliobolus pathogens.";
RL PLoS Genet. 9:E1003233-E1003233(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448};
CC -!- PATHWAY: Glycan metabolism; cellulose degradation.
CC {ECO:0000256|ARBA:ARBA00004987}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
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DR EMBL; KB445650; EMD60394.1; -; Genomic_DNA.
DR RefSeq; XP_007703594.1; XM_007705404.1.
DR AlphaFoldDB; M2QZB2; -.
DR SMR; M2QZB2; -.
DR STRING; 665912.M2QZB2; -.
DR GeneID; 19139627; -.
DR KEGG; bsc:COCSADRAFT_40034; -.
DR eggNOG; ENOG502QR4D; Eukaryota.
DR HOGENOM; CLU_004542_2_0_1; -.
DR OMA; YYPSPWA; -.
DR OrthoDB; 5486783at2759; -.
DR Proteomes; UP000016934; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR026891; Fn3-like.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42715; BETA-GLUCOSIDASE; 1.
DR PANTHER; PTHR42715:SF12; BETA-GLUCOSIDASE A-RELATED; 1.
DR Pfam; PF14310; Fn3-like; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SMART; SM01217; Fn3_like; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EMD60394.1};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000016934};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..869
FT /note="beta-glucosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012949180"
FT DOMAIN 786..854
FT /note="Fibronectin type III-like"
FT /evidence="ECO:0000259|SMART:SM01217"
SQ SEQUENCE 869 AA; 94233 MW; 4F32FAB8106D8C98 CRC64;
MLWLAQALLV GLAQASPRFP RATNDTGSGS LNNAQSPPFY PSPWVDPTTK DWAAAYEKAK
AFVSQLTLIE KVNLTTGTGW QSDHCVGNVG AIPRLDFDPL CLQDSPLGIR FADYVSAFPA
GGTVAASWDR YEFYTRGNEM GKEHRKKGVD IQLGPAIGPL GRHPKGGRNW EGFSPDPVLS
GIAVAETVRG IQDAGVIACT KHYLLNEQEH FRQPGGFKDI PFVDAISSNT DDKTLHELYL
WPFADAVRAG TGSIMCSYNK ANNSQVCQNS YLQNYILKGE LGFQGFILSD WDAQHSGVAS
AYAGLDMTMP GDTGFNSGLS FWGTNLTVSI LNGTIPQWRL DDAAIRIMAA YYFVGLDESI
PVNFDSWQTS TYGFEHFFGK KSFGLVNKHV DVREEHFRSI RRSAAKSTVL LKNSGVLPLS
GKEKWTAVFG EDAGENPLGP NGCADRGCNS GTLAMGWGSG TADFPYLITP LEAIKREVNE
NGGMITSVTD NYATSQIQNM ASRASHSIVF VNADSGEGYI TVDNNMGDRN NLTVWGNGDV
LVKNVSALCN NTIVVIHSVG PVIVDAWKEN ANVTAILWAG LPGQESGNSI ADILYGHHNP
GGKLPFTIGS SAEEYGPDII YEPTNGILSP QANFEEGVFI DYRAFDKAGI EPTYEFGFGL
SYTTFEYSDI KVTAQSAKAY KPFTGQTSAA PTFGNFSKNP EDYQYPPGLV YPDTFIYPYL
NSTDLKTASQ DPEYGLNVTW PKGSTDGSPQ ARIAAGGAPG GNPQLWDVLF KVEATITNTG
DVAGDEVAQA YISLGGPHDP KVQLRDFDRL TIQPGESVVF TANITRRDVS NWDTVSQNWV
ITEYPKTIHV GASSRNLPLS APLDTSSFK
//
