ID M2SAU1_9SPHN Unreviewed; 785 AA.
AC M2SAU1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpA {ECO:0000313|EMBL:EMD82505.1};
GN ORFNames=C725_2226 {ECO:0000313|EMBL:EMD82505.1};
OS Pacificimonas flava.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingosinicellaceae; Pacificimonas.
OX NCBI_TaxID=1234595 {ECO:0000313|EMBL:EMD82505.1, ECO:0000313|Proteomes:UP000011717};
RN [1] {ECO:0000313|EMBL:EMD82505.1, ECO:0000313|Proteomes:UP000011717}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JLT2015 {ECO:0000313|EMBL:EMD82505.1,
RC ECO:0000313|Proteomes:UP000011717};
RX PubMed=23661488;
RA Tang K., Liu K., Li S., Jiao N.;
RT "Draft Genome Sequence of Strain JLT2015T, Belonging to the Family
RT Sphingomonadaceae of the Alphaproteobacteria.";
RL Genome Announc. 1:E00226-13(2013).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMD82505.1}.
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DR EMBL; AMRV01000007; EMD82505.1; -; Genomic_DNA.
DR RefSeq; WP_008602840.1; NZ_JACHGC010000007.1.
DR AlphaFoldDB; M2SAU1; -.
DR PATRIC; fig|1234595.3.peg.2229; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000011717; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0043335; P:protein unfolding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR013461; ClpA.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02639; ClpA; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF111; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Hydrolase {ECO:0000313|EMBL:EMD82505.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:EMD82505.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011717};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..146
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT REGION 144..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 785 AA; 85975 MW; 34537F32BF38CCEA CRC64;
MPAFSRELEN TLHNALAEAS RRTHEYATLE HLLFALIADN HAGAVIRACG VDTDVLAGQL
TEYLDTELEP LRTSEAIDPN PTAGFQRVVQ RAILHVQSSG RDEVTGANVL VALFSERESH
AVYFLQQQDM TRLDAVSYLS HGIAKSGGSE SRPARGAEEE TAEAGAKKGK KKAESPLDQF
TVNLNARAES GKIDPLIGRQ GEVDRTVQIL CRRSKNNPLY VGDPGVGKTA IAEGLARRIV
EGDVPEVLQE AVIYALDMGA LLAGTRYRGD FEERLKGVVS ELEDMPHAVL FIDEIHTVIG
AGATSGGAMD ASNLLKPALS SGAIRCIGST TYKEFRNHFE KDRALLRRFQ KIDVAEPTVE
DAIKIIQGLK PYFEEHHDVR YTNDALKAAV ELSARYINDR KLPDKAIDVI DEVGASQNLV
AKSKRKKTMG VKEVESVIAT MARIPPKSVS KDDKMQLATL EQDLKRVVFG QDKAIEILSS
AIKLSRAGLR EPNKPIGNYL FSGPTGVGKT EVAKQLSSIM GIPLHRFDMS EYMERHSVSR
LIGAPPGYVG YDQGGQLTDA VDQSPHCVLL LDEIEKAHPD LFNILLQVMD AGKLTDHHGK
TVDFRNVILI MTTNAGAAEM AREAIGFGVS AREGEDEEAI KRMFSPEFRN RLDAVVPFDY
LPTEVVAMVA EKFVLELELQ LADREVHISL ADDAKDWLVQ RGYDKLYGAR PMARLIQTEI
KQPLAEELLF GRLMHGGEVV VHLKDGKPAF EITAAPPKGT KKKGRGKTPK TQSAGGDDEG
DKVDA
//
