ID M2SEP4_COCSN Unreviewed; 730 AA.
AC M2SEP4;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Mitochondrial outer membrane transport complex Sam37/metaxin N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=COCSADRAFT_114916 {ECO:0000313|EMBL:EMD65758.1};
OS Cochliobolus sativus (strain ND90Pr / ATCC 201652) (Common root rot and
OS spot blotch fungus) (Bipolaris sorokiniana).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX NCBI_TaxID=665912 {ECO:0000313|EMBL:EMD65758.1, ECO:0000313|Proteomes:UP000016934};
RN [1] {ECO:0000313|EMBL:EMD65758.1, ECO:0000313|Proteomes:UP000016934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ND90Pr / ATCC 201652 {ECO:0000313|Proteomes:UP000016934};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
RN [2] {ECO:0000313|Proteomes:UP000016934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ND90Pr / ATCC 201652 {ECO:0000313|Proteomes:UP000016934};
RX PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT "Comparative genome structure, secondary metabolite, and effector coding
RT capacity across Cochliobolus pathogens.";
RL PLoS Genet. 9:E1003233-E1003233(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004294}.
CC -!- SIMILARITY: Belongs to the metaxin family.
CC {ECO:0000256|ARBA:ARBA00009170}.
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DR EMBL; KB445641; EMD65758.1; -; Genomic_DNA.
DR RefSeq; XP_007698816.1; XM_007700626.1.
DR AlphaFoldDB; M2SEP4; -.
DR STRING; 665912.M2SEP4; -.
DR GeneID; 19130264; -.
DR KEGG; bsc:COCSADRAFT_114916; -.
DR eggNOG; KOG3028; Eukaryota.
DR HOGENOM; CLU_022774_0_0_1; -.
DR OMA; ATIAYCH; -.
DR OrthoDB; 2723944at2759; -.
DR Proteomes; UP000016934; Unassembled WGS sequence.
DR GO; GO:0001401; C:SAM complex; IEA:InterPro.
DR CDD; cd03193; GST_C_Metaxin; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR033468; Metaxin_GST.
DR InterPro; IPR028245; PIL1/LSP1.
DR InterPro; IPR019564; Sam37/metaxin_N.
DR PANTHER; PTHR31962; SPHINGOLIPID LONG CHAIN BASE-RESPONSIVE PROTEIN PIL1; 1.
DR PANTHER; PTHR31962:SF1; SPHINGOLIPID LONG CHAIN BASE-RESPONSIVE PROTEIN PIL1; 1.
DR Pfam; PF17171; GST_C_6; 1.
DR Pfam; PF13805; Pil1; 1.
DR Pfam; PF10568; Tom37; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000016934}.
FT DOMAIN 21..147
FT /note="Mitochondrial outer membrane transport complex
FT Sam37/metaxin N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10568"
FT DOMAIN 232..293
FT /note="Metaxin glutathione S-transferase"
FT /evidence="ECO:0000259|Pfam:PF17171"
FT REGION 651..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 545..572
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 709..730
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 80439 MW; D0E731644C11E5CF CRC64;
MVLELHVWGP AFGLASIEAE CIATIAYCHR VIPEGGWSLV ASHNPTVGTA EILPILFDDG
VATASGFEDI VAYLRNYPTV TNDIDAGLSS AQRTDRTAFG TFLQATATPL VDLSLYVSAE
NYNKTTASAY TAILPWYANY TVPPRRRDLA RMRTAHMGLS SLDVDTSAEE EFAPGRGTAS
SEYEAAKRAA GIPTESQPRS LNIGRGRGLG GLLGGQVYAA RFRLDALSAE LLDPLSDLLG
KNKYLFRGDQ PSSLDCLAFG YLSLLIYPPV PQAWLRETIR AKYPRIGAYV HRLHRDLFHE
EEVSPADIWA VSTGKSNIAT STTLPWTTRP ASFGASAMAC TKEILGNLPG IATVSQKRTI
VTSEPMLVSK RFRSELPSPL FLSSVFGSRA PTASQIQNPP PPASSTKSGR FFGKANIGHT
FRHKSAGAFG PDLAKKLSQL VKMEKNVMRS MELVSRERME VAQQLSIWGE ACDDDVSDVT
DKLGVLIYEI GELEDQYVDR YDQYRVTIKS IRNIEASVQP SRDRKQKITD QIAQLKYKEP
NSPKIVVLEQ ELVRAEAESL VAEAQLSNIT REKLKAAFTY QFDAMREHCE KLAIIAGYGK
HLLELVDDTP VTPGETRQAY DGYEASKAII QDCEDALTNW VSQNASVSAK LSQRSRTLSQ
RRRNQSRGHG EGVDLSGQDQ ALDRESGLWI PASEHQGNGY EDRDELDDEN TSTIASEHHR
GREEERMVAA
//
