ID M2TH24_COCH5 Unreviewed; 466 AA.
AC M2TH24;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=D-serine dehydratase-like domain-containing protein {ECO:0000259|SMART:SM01119};
GN ORFNames=COCHEDRAFT_1199617 {ECO:0000313|EMBL:EMD96745.1};
OS Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O) (Southern
OS corn leaf blight fungus) (Bipolaris maydis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX NCBI_TaxID=701091 {ECO:0000313|EMBL:EMD96745.1, ECO:0000313|Proteomes:UP000016936};
RN [1] {ECO:0000313|EMBL:EMD96745.1, ECO:0000313|Proteomes:UP000016936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C5 / ATCC 48332 / race O {ECO:0000313|Proteomes:UP000016936};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
RN [2] {ECO:0000313|Proteomes:UP000016936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C5 / ATCC 48332 / race O {ECO:0000313|Proteomes:UP000016936};
RX PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT "Comparative genome structure, secondary metabolite, and effector coding
RT capacity across Cochliobolus pathogens.";
RL PLoS Genet. 9:E1003233-E1003233(2013).
CC -!- SIMILARITY: Belongs to the DSD1 family.
CC {ECO:0000256|ARBA:ARBA00005323}.
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DR EMBL; KB445569; EMD96745.1; -; Genomic_DNA.
DR AlphaFoldDB; M2TH24; -.
DR STRING; 701091.M2TH24; -.
DR eggNOG; ENOG502QWI8; Eukaryota.
DR HOGENOM; CLU_031639_0_0_1; -.
DR OMA; EIRPGNF; -.
DR Proteomes; UP000016936; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProt.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR Gene3D; 2.40.37.20; D-serine dehydratase-like domain; 1.
DR InterPro; IPR001608; Ala_racemase_N.
DR InterPro; IPR026956; D-ser_dehydrat-like_dom.
DR InterPro; IPR042208; D-ser_dehydrat-like_sf.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR28004:SF2; D-SERINE DEHYDRATASE; 1.
DR PANTHER; PTHR28004; ZGC:162816-RELATED; 1.
DR Pfam; PF01168; Ala_racemase_N; 1.
DR Pfam; PF14031; D-ser_dehydrat; 1.
DR SMART; SM01119; D-ser_dehydrat; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000016936}.
FT DOMAIN 333..448
FT /note="D-serine dehydratase-like"
FT /evidence="ECO:0000259|SMART:SM01119"
SQ SEQUENCE 466 AA; 50163 MW; F7D080695B46A823 CRC64;
MSGPSTLQNY PLPSSSSLAA QFVGKTLNEL PTPAVVLDRA LIKRNCNAML NVCKELGVGF
RAHVKSHKTA ELSKLQVGEQ GAANFIVSTI IEAEHLAEVV LEEQGKGRDA SILYGVPVPQ
SGIPRLIALA EKLKPRSVSL IIDNQDAFLK LFQRLAASES QVELGIFIKI DTGYERAGIK
TSSPSFPTLV STIISKTQET GSKCFLQGFY SHFGHSYAGS SEDDAANGLI EELIGLEAAT
KAVPASFAGK LVLSVGATPT ATAAQNMLSR TSPRVREFQT VLSRLQAQHL VELHAGVYPL
LDCQQVATHA RPPTFSSAEP TPAFQPLSKS NIGIRMLLEV TSVYNERAKP EALVSAGSLA
MGREPCKSYA GWGIVTPDLG NSSAKHIYDE QAGRTGWTVG RISQEHGVLT WEGDRDACND
LVIGDKVMVW PNHACVAGAG FGWYLVIDSE GHGETVVDVW VRWRGW
//
