ID M2THX1_COCSN Unreviewed; 1128 AA.
AC M2THX1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Nephrocystin-3 {ECO:0000256|ARBA:ARBA00040387};
GN ORFNames=COCSADRAFT_157220 {ECO:0000313|EMBL:EMD68816.1};
OS Cochliobolus sativus (strain ND90Pr / ATCC 201652) (Common root rot and
OS spot blotch fungus) (Bipolaris sorokiniana).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX NCBI_TaxID=665912 {ECO:0000313|EMBL:EMD68816.1, ECO:0000313|Proteomes:UP000016934};
RN [1] {ECO:0000313|EMBL:EMD68816.1, ECO:0000313|Proteomes:UP000016934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ND90Pr / ATCC 201652 {ECO:0000313|Proteomes:UP000016934};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
RN [2] {ECO:0000313|Proteomes:UP000016934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ND90Pr / ATCC 201652 {ECO:0000313|Proteomes:UP000016934};
RX PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT "Comparative genome structure, secondary metabolite, and effector coding
RT capacity across Cochliobolus pathogens.";
RL PLoS Genet. 9:E1003233-E1003233(2013).
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DR EMBL; KB445638; EMD68816.1; -; Genomic_DNA.
DR RefSeq; XP_007696325.1; XM_007698135.1.
DR AlphaFoldDB; M2THX1; -.
DR GeneID; 19131815; -.
DR KEGG; bsc:COCSADRAFT_157220; -.
DR eggNOG; KOG1840; Eukaryota.
DR HOGENOM; CLU_000288_125_4_1; -.
DR OMA; VHRFMAD; -.
DR OrthoDB; 1944802at2759; -.
DR Proteomes; UP000016934; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR010730; HET.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45641:SF1; NEPHROCYSTIN-3; 1.
DR PANTHER; PTHR45641; TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870); 1.
DR Pfam; PF06985; HET; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13374; TPR_10; 2.
DR Pfam; PF13424; TPR_12; 4.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00028; TPR; 10.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016934};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT DOMAIN 280..437
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 1128 AA; 126994 MW; B3195FDA4DB06360 CRC64;
MRLLHLNALG RLILTDFRGK PIPPYAILSH RWGDSEILIE DIFNGNYKKK EEGYQKLRFC
AEQAAQDGLQ YFWIDTCCID RWNNSERSKA INSMFQWYKN AVRCYVFLSD VSASTLTSIG
SVLCRDWNIS LRRSKWFTRG WTLQELIAPA SVEFFSCEGQ WIGDKTSLDQ LLHSITSIPP
AALRNCPLNQ FSISERMRWV SGRETTETED MVYCLLGLLS VSMPATYGEG RESALERLQA
EVEGAGLAPS IIPFARNKSF VGRELQLAEL EAKLFSNTQT TSTLAIVGSG GTGKSQLALE
VAHRTRKKHK HCSVFWIDAS DKDSLDQSYT SVAQKLSVPS YDSDQADTEQ IVKHCIAKLS
TRQCLLIFDN VKNTTVQHSG SSTAEAADLA DFLPQSKLCS VVFTTTESDT AKTLAPQDVV
ALRELTSDTA LRMLQSRLTT PLSNAEQPGA IRLLRELSHL PLAVSQAAAC INASNITVQQ
YHARLHEHDK AALKHSNNLG KGEQGESSLK KAVAATLSLS IGQVWQSNAI AAEQLYIAAC
VDRKDIPLDL LEAASPQARV DAIMILDRYA LITRRPAESA FDVHRLVHQA LQEQLHMQGR
LHEFTQRAVT RLLQVFPNND YSNRSKWRRL LPHAQYALSH SEKNDNEERT NLTENCARAL
QSDGQYKRAE ELYMQVMESR KRVLGSKHPD TLVSVNNLGL VLEDQGKYEE AEAMHRRVLE
AREKVLGREH PDTLTSVSNL GSVLEKQAKY EEAEAMHQRA LEAREKVLGR EHPDTLTSVS
KLGVVLEKQG KYEEAEAMHR RDLEAREKVL GREHPDTLTS VSKLGVVLER QGKYEEAEAM
HRRDLEGSEK VLGREHPDTL TSVSNLGSVL EKQGKYEEAE AMHRRVLEGY EKVLGREHPY
TLTSVSNLGL VLERQGKYKE AEAMHQRALE AREKVLGREH PDTLTSVSNL GLVLERQGKY
EEAEAMHRRA LEGSEKVLGR EHPDTLTSVS NLGSVLERQS KYEEAEAMHQ QALEAREKVL
GREHPHTLTN INNLGLVLER QGKYEEAEAM HRRALEAREK VLGREHPHTL TSVYCLAHLL
ATLCDYKESL NLYNRACDGY SVVFGEHHPT TRACRQHRSE VLLSCKQS
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