ID M2TV60_COCH5 Unreviewed; 1271 AA.
AC M2TV60;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
GN ORFNames=COCHEDRAFT_1187374 {ECO:0000313|EMBL:EMD85651.1};
OS Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O) (Southern
OS corn leaf blight fungus) (Bipolaris maydis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX NCBI_TaxID=701091 {ECO:0000313|EMBL:EMD85651.1, ECO:0000313|Proteomes:UP000016936};
RN [1] {ECO:0000313|EMBL:EMD85651.1, ECO:0000313|Proteomes:UP000016936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C5 / ATCC 48332 / race O {ECO:0000313|Proteomes:UP000016936};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
RN [2] {ECO:0000313|Proteomes:UP000016936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C5 / ATCC 48332 / race O {ECO:0000313|Proteomes:UP000016936};
RX PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT "Comparative genome structure, secondary metabolite, and effector coding
RT capacity across Cochliobolus pathogens.";
RL PLoS Genet. 9:E1003233-E1003233(2013).
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DR EMBL; KB445587; EMD85651.1; -; Genomic_DNA.
DR AlphaFoldDB; M2TV60; -.
DR STRING; 701091.M2TV60; -.
DR eggNOG; KOG0504; Eukaryota.
DR eggNOG; KOG2029; Eukaryota.
DR HOGENOM; CLU_000288_34_1_1; -.
DR OMA; WLRYYWA; -.
DR Proteomes; UP000016936; Unassembled WGS sequence.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24123:SF33; ANKYRIN 2, ISOFORM U; 1.
DR PANTHER; PTHR24123; ANKYRIN REPEAT-CONTAINING; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13637; Ank_4; 3.
DR Pfam; PF05729; NACHT; 1.
DR SMART; SM00248; ANK; 9.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000016936};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 380..535
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT REPEAT 1000..1025
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1102..1135
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1204..1236
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1271 AA; 142909 MW; 33ED7522372E378C CRC64;
MLELRKKLRK LKRKELTPEV PQKPQQFSQG QVPATEHKKS YGLFLLHENA LPDDSKDYIG
VDVVAIHGLN GDAYTTWRHE NGTLWLRDLL PSALPGSRVF TYGYPSELFW SNSVATLRDY
SGNLLSSLGA VWEGRQRPII FVCHSLGGIV CKQALVMAHE DDRLHGNILS AVSAIVFFGT
PHRGSRGADV RKAIARVINM CMRVPGITGI VGSIRDDLLT TLESNSRALN DLAVSSRNRL
RDLEIVTFYE TQTIPGLSEL VVPQTSAILE IPCEDVISLY ANHRTMCRFG GAADSNYSQV
LNVMKRLAKT ALLNREMTMT VDRTSSNQSL SETERSCMVL LNSIYLVEYK AQLPTPVQGT
CSWVLTHPAY LTWLKTEETK LLWITGEPGC GKTMLSAYIT DHLRLDHATS VKPSVFFFFC
DDKVKSQRDA NAILRGILYQ IVQQHRKLIK YVKSRFETDG PSLANSFPAL WELFLKIISN
SASGAVRVIV DAIDECEVRT RNSFLKAIMQ LVNDSQDVYR QSRNCVKFLI TSRPSLGNSY
DLTGSLKNRL SIEEDQGIVS EDLRLVIRSK VADIAKKFNC DEETRSYLER VLYSKSDQSF
LWLNMVLHSL ETSSKASRRD FERIIDTFPR SLQATYDGFL SRISIENQED AGKILRLLVG
CSRYLTLVEI NTAFTIDQDH ESIADVVNDL QHSISTTLQN IVGSFVRIRE INYTSNQDSK
VSLVHQSAKE YLTDLALRSA EKTVKSLAVS LPNAALEISQ SCIRYLLLEE FQLDIFAPEG
TSRGTNSPES YRSFPYTDFD TTAPDDHLGL DNLGLDDHLG LESFFKNSRD LDEDQSALTA
QKYKFFDYAA THWAEHYSLC EDIAPKTVQD AVKELTKSSG YVLTNWLKYY WFKNNMEYSF
PDVFETIEVA AFFNLSILLA EILEKAEFDS DAKKVQALFW AARRSSLKCM KVLLQHDTNP
NGIGTDRQTP LTISAQYGHL DAVQILLDEP FTDVTLKGKS GRSALSFAAG NGHLEIVEVL
LKHEALRLND QDNARWTPLF WAVIGDHAKV VQLLLRQSCI HINEVDKHGR SVLSWAAGEG
AGRALKVLLR HPSIDLNLRD IKGLSPLLWA ARNGQREIVS ILVHKTGVDK AAKDKDLRNA
ISWACQGGHT DTLRILLKNN CGGEDDVDVD TWTPLLWALF DRSPATVEVL LSSQRVQIDR
QDGYGRTALI WAASYGYLDV VQLLISWKAN VLIKNHGGHA AADVARMEGH TEVWEFLEAQ
QRKELEKSVD E
//
