ID   M2U228_9SPHN            Unreviewed;       500 AA.
AC   M2U228;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN   ORFNames=C725_2739 {ECO:0000313|EMBL:EMD81843.1};
OS   Pacificimonas flava.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingosinicellaceae; Pacificimonas.
OX   NCBI_TaxID=1234595 {ECO:0000313|EMBL:EMD81843.1, ECO:0000313|Proteomes:UP000011717};
RN   [1] {ECO:0000313|EMBL:EMD81843.1, ECO:0000313|Proteomes:UP000011717}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JLT2015 {ECO:0000313|EMBL:EMD81843.1,
RC   ECO:0000313|Proteomes:UP000011717};
RX   PubMed=23661488;
RA   Tang K., Liu K., Li S., Jiao N.;
RT   "Draft Genome Sequence of Strain JLT2015T, Belonging to the Family
RT   Sphingomonadaceae of the Alphaproteobacteria.";
RL   Genome Announc. 1:E00226-13(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMD81843.1}.
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DR   EMBL; AMRV01000013; EMD81843.1; -; Genomic_DNA.
DR   AlphaFoldDB; M2U228; -.
DR   OrthoDB; 9781481at2; -.
DR   Proteomes; UP000011717; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000011717}.
FT   DOMAIN          15..160
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   500 AA;  56050 MW;  2D570AB2F4D755BF CRC64;
     MSDKLSAEGA CRLGTRDKIF ISHATPGDNA FAIWLSSRLS MAGFDVWCDA KKLLGGEDFW
     QEIERTLRNE TAKFLIVISH SAFGSENVLR DGIAKELALA DIVKKQISDP HFIVPVRLDD
     TSYGDFSIEL IRTNGVDCSE NWANGLARVL EIFDRDKVPQ SGAASESLAA WRSVHQHHTR
     AISDTPEILQ SNWLPVTEYP ETLYFYESPG VRWTLEPRVI ASQCTIPAFA HGRLLASFAQ
     LDEMQAAAGS EFPIRDRGNL PLKDYLRGRT GDILGVSPFD ARNQISSLVR QAWDLKMAKL
     GLWNYALANG QLTWWFPRNV PEDGQLRYTD FNGKERKRAS TGIKGQKELP DGQQVPRNYW
     HLGFTAQPML GDPKVMRLQP RIVITEDGRT PLANKTRLNS VRRSLTKMWF NDKWRGLFLG
     FVNFVAKGEA TIRLPVSSGE DVAISSQPVS FPLSCGISTD PIDQNLSDEL AEVFEEAEQA
     MRLTDPVFSS LLVDEEGEDE
//