ID M2UF93_COCH5 Unreviewed; 1172 AA.
AC M2UF93;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=COCHEDRAFT_1124333 {ECO:0000313|EMBL:EMD97169.1};
OS Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O) (Southern
OS corn leaf blight fungus) (Bipolaris maydis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX NCBI_TaxID=701091 {ECO:0000313|EMBL:EMD97169.1, ECO:0000313|Proteomes:UP000016936};
RN [1] {ECO:0000313|EMBL:EMD97169.1, ECO:0000313|Proteomes:UP000016936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C5 / ATCC 48332 / race O {ECO:0000313|Proteomes:UP000016936};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
RN [2] {ECO:0000313|Proteomes:UP000016936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C5 / ATCC 48332 / race O {ECO:0000313|Proteomes:UP000016936};
RX PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT "Comparative genome structure, secondary metabolite, and effector coding
RT capacity across Cochliobolus pathogens.";
RL PLoS Genet. 9:E1003233-E1003233(2013).
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DR EMBL; KB445569; EMD97169.1; -; Genomic_DNA.
DR AlphaFoldDB; M2UF93; -.
DR STRING; 701091.M2UF93; -.
DR eggNOG; KOG1166; Eukaryota.
DR HOGENOM; CLU_002115_1_0_1; -.
DR OMA; NCEKGVG; -.
DR Proteomes; UP000016936; Unassembled WGS sequence.
DR GO; GO:0000776; C:kinetochore; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR CDD; cd13981; STKc_Bub1_BubR1; 1.
DR Gene3D; 1.25.40.430; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR015661; Bub1/Mad3.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR013212; Mad3/Bub1_I.
DR InterPro; IPR012572; Mad3/Bub1_II.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR14030:SF4; BUB1 KINASE, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR14030; MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1; 1.
DR Pfam; PF08311; Mad3_BUB1_I; 1.
DR Pfam; PF08171; Mad3_BUB1_II; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00777; Mad3_BUB1_I; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51489; BUB1_N; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016936}.
FT DOMAIN 63..222
FT /note="BUB1 N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51489"
FT DOMAIN 834..1169
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 237..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 512..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 717..752
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..467
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..542
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..573
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 574..599
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 633..647
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1172 AA; 131317 MW; 2FD1394E300DB952 CRC64;
MGSDDLIDFE VIENQKENIQ SLPSGRSAKA LAQLYTPPLT SAAGQAPSPS QMQDANSATR
LQYEKELMAI DDSDDPLDVY DRYVKWTLDA YPSAQNTPQS QLCPLLERAT KTFQSSPQYK
NDARYLKLWL HYIHLFSDAP RETFAYLARH HIGEELALYY EEFAAWLESA GRYAQAEEVY
NMGIERGARP TERLIRKYGE FQHRCESRPQ QAEEPTSPAL PAVRPALAAK VDPFALASPS
APAPQAQAQP KPAAGTSRSG KAKLAIFADG DDAAKPTSSG STEGWGNIGS LADRKKENAQ
EARPWAGETL KVGKKNTGVP KMAIFKDESK SNLNDENVNS HPLREYQQAV NPRTGRLEVV
FVDLEKVYPN HEDPMSEEYS FEELRAKHRG WLDRDWAAMR RQEEQARKDA EAALAAAQTK
PKAMPLAPKQ EPEPIAKPQT VPLKGSARRE ERANRTRKIK VMETKEIRGE TQTIQANLDS
PAKSKMRRKK AGPEMTMTLH TKEAMDEIYD IFNEPLKNAD DNASEVQSGE ESSEDDEDDY
SSGAESTGTG RISGATSEYG DETTSVSESS DFTEIKPGQK DDEQDQSENE SEHSGQSQDD
SFDETSNVDG ESEHQQDERV VTPTSPSGPR SLPTRFVPVP PEDYNPAMRP YRDPVVVANN
RLPFMTPIVE KTESSLGIAT AVAQKEYYAA KTPSRSPFSD ILGQVIDGPG KVAKLALTDS
KPVPKEPLDE PQRKPLAAKE PPVTVARPSG PIIKDTQCNP VDDSIRKTIL QETQPPLESY
EGYYADTEQS YGKGADIRKY TKAVSKLSKN AQDKTAANVG ACPTLEFPGT ERTYVVKREL
GKGAFAPVYL VESKEAENDE NKPSQMGKGE FGPKRQHLEA IKMEDPPTPW EFYIMRQAKR
RLGVSRAAES VVSAYEMHVF KDECYLVEEY RDQGTLLDLV NHARADNGAM DEQLAMFFTI
ELFRTVEALH SKGIIHGDLK SDNVLVRFDA LQKDEHWDSE YKRDGRDGWS AKGISLIDFG
RGIDMKAFKP EVQFIADWPT TEADCAEMRE LRPWTHQIDY HGLAGIVHNL LFGKYISAVA
ERGATLGSGA TKTYKIKENL KRYWQTEIWH ECFDLLLNPL MHLEGEEGRR LPVLKGMKEL
REKMEEYLEN NCEKGVGLKV LVRRMEEVVK RR
//
