ID M2UNU3_COCH5 Unreviewed; 1247 AA.
AC M2UNU3;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 4 {ECO:0000256|ARBA:ARBA00020975};
DE AltName: Full=Component of oligomeric Golgi complex 4 {ECO:0000256|ARBA:ARBA00031340};
GN ORFNames=COCHEDRAFT_1168970 {ECO:0000313|EMBL:EMD95256.1};
OS Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O) (Southern
OS corn leaf blight fungus) (Bipolaris maydis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX NCBI_TaxID=701091 {ECO:0000313|EMBL:EMD95256.1, ECO:0000313|Proteomes:UP000016936};
RN [1] {ECO:0000313|EMBL:EMD95256.1, ECO:0000313|Proteomes:UP000016936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C5 / ATCC 48332 / race O {ECO:0000313|Proteomes:UP000016936};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
RN [2] {ECO:0000313|Proteomes:UP000016936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C5 / ATCC 48332 / race O {ECO:0000313|Proteomes:UP000016936};
RX PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT "Comparative genome structure, secondary metabolite, and effector coding
RT capacity across Cochliobolus pathogens.";
RL PLoS Genet. 9:E1003233-E1003233(2013).
CC -!- SIMILARITY: Belongs to the COG4 family.
CC {ECO:0000256|ARBA:ARBA00009215}.
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DR EMBL; KB445571; EMD95256.1; -; Genomic_DNA.
DR AlphaFoldDB; M2UNU3; -.
DR STRING; 701091.M2UNU3; -.
DR eggNOG; KOG0412; Eukaryota.
DR HOGENOM; CLU_006939_0_0_1; -.
DR OMA; RASECQQ; -.
DR Proteomes; UP000016936; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.58.1970; -; 1.
DR Gene3D; 1.50.10.10; -; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR048682; COG4.
DR InterPro; IPR048684; COG4_C.
DR InterPro; IPR013167; COG4_M.
DR InterPro; IPR048680; COG4_N.
DR InterPro; IPR008313; GH125.
DR PANTHER; PTHR24016; CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4; 1.
DR PANTHER; PTHR24016:SF0; CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4; 1.
DR Pfam; PF20662; COG4_C; 1.
DR Pfam; PF08318; COG4_m; 1.
DR Pfam; PF20663; COG4_N; 1.
DR Pfam; PF06824; Glyco_hydro_125; 1.
DR SMART; SM00762; Cog4; 1.
DR SMART; SM01149; DUF1237; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Hydrolase {ECO:0000313|EMBL:EMD95256.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000016936};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 171..512
FT /note="COG4 transport protein middle alpha-helical bundle"
FT /evidence="ECO:0000259|SMART:SM00762"
FT REGION 331..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1247 AA; 138211 MW; BB7A2EAC9417ACB6 CRC64;
MAVDITDPHD IFAAASVAQI HAALSQLHDH EAAVTRQLNT LIASQKDLSR ELGRLDLLRA
HLGTQTVNTR AISNGMLSDA ASTATRISGA VKRLDQEQSN VKATLHVVEQ VAELKACVLG
VHGSMGAPQD WETAAGYLSR AAKIPDDVVN GSFAEEIVPT AEVPDPPRVT LDAAAESLCG
LFLREFEKAA KDGDGSKVTR FFKLFPLIGR TDVGLDAYGR YVCQGVASRA RANFNSASPA
QRNEGFFYGN TITKLFEHIA QIVDGHEPLV ERHYGPGMMQ KVIERLQIEA DVQGGIVLDT
WHEERHIDRK LTDIKSYAFS FLVQSFLPAQ KPSSGTPRAS SPANGVARTS EDEGVDMKEI
DALLGEGALI LGRYALYARF ISDKCAPAEP EEHIDYGLVM PNFLATSNLH KKVNSHLIEP
VNAMTTFFFR RSVEKAFQLD ESPSDLTLNP NKPLGSNPPF ITSAVDDVMY IVNQVLQRTL
ATSQRAVVAS VVPAVSHILG AEFIGMIQRK MRDESYPKPV IQGGLPPEDK VIAFLVLINN
LDIANDYVKR IVQQQLRIQP QPGQEDAHSP LQDLFPFGHD ATFVENTLRS MEKSFAAKSG
DLLNDGITVL FSNVLKPRIR PILAEAFRDI RYDPGGEDAN DDEDIDDTDI VKARFDRGWG
VVIRPIKRIL TPANFDRLLA LGLNYLASAL EKRIKSYYGR VNELGAVRLE RDISGIITAA
TSGGAYALRD AFQKCTQMTL ILNMEDDEFE QVAIDDAAGE SGISWVLDLE ERNRCPLYQN
YANQRHEPFS TGKWSLSYAR PIEPCRTFRA PEVEETIGRL RDVIKDPDLF RLFENTWPST
LDTTIAWRGL SDSFSNTIKQ EELTFVITGD IQAIHDSLAS LFRGAINLQA RYILGNAFCN
AFQAPDESGI PQRSSKNDDR ITPPYDYFKV FSCQWELDSV ASFLQLSTDY ATATRDYEFF
QNSSNWTKAV ELILDTAESM MIDSYSADGV WQHTPYTYCA PYGGTPINDC NGSPHRGNLG
LVRSFHRPSD DACTYQYLIP SNMMFSSALN TSSVIMSRVE ASSSGTLTTR MQQMSTGINR
GIEKYGLAND PTHGKIYAYE VDGYGGANIM DDPNVPSLLS APYIGYTTIH DPIYQNTRSK
VLSRDNPYYA VGPAITGVAS PHTLPGKPWP MALIMTILTS EDDDEITRNL RWLVSSTDGL
GLMHESVDAR NAGVWSRQWF SWANGLMGQM ILDLEKRKPH LLQLSFQ
//
