ID M2WUT7_GALSU Unreviewed; 777 AA.
AC M2WUT7;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=DNA excision repair protein ERCC-2 {ECO:0000313|EMBL:EME27730.1};
GN ORFNames=Gasu_47180 {ECO:0000313|EMBL:EME27730.1};
OS Galdieria sulphuraria (Red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Galdieriales; Galdieriaceae;
OC Galdieria.
OX NCBI_TaxID=130081 {ECO:0000313|EMBL:EME27730.1, ECO:0000313|Proteomes:UP000030680};
RN [1] {ECO:0000313|Proteomes:UP000030680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=074W {ECO:0000313|Proteomes:UP000030680};
RX PubMed=23471408; DOI=10.1126/science.1231707;
RA Schonknecht G., Chen W.H., Ternes C.M., Barbier G.G., Shrestha R.P.,
RA Stanke M., Brautigam A., Baker B.J., Banfield J.F., Garavito R.M., Carr K.,
RA Wilkerson C., Rensing S.A., Gagneul D., Dickenson N.E., Oesterhelt C.,
RA Lercher M.J., Weber A.P.;
RT "Gene transfer from bacteria and archaea facilitated evolution of an
RT extremophilic eukaryote.";
RL Science 339:1207-1210(2013).
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DR EMBL; KB454528; EME27730.1; -; Genomic_DNA.
DR RefSeq; XP_005704250.1; XM_005704193.1.
DR AlphaFoldDB; M2WUT7; -.
DR STRING; 130081.M2WUT7; -.
DR EnsemblPlants; EME27730; EME27730; Gasu_47180.
DR GeneID; 17086616; -.
DR Gramene; EME27730; EME27730; Gasu_47180.
DR KEGG; gsl:Gasu_47180; -.
DR eggNOG; KOG1132; Eukaryota.
DR OMA; GNCATIV; -.
DR OrthoDB; 124793at2759; -.
DR Proteomes; UP000030680; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd18788; SF2_C_XPD; 1.
DR Gene3D; 1.10.275.40; -; 1.
DR Gene3D; 1.10.30.20; Bacterial XPD DNA helicase, FeS cluster domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR006554; Helicase-like_DEXD_c2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR InterPro; IPR013020; Rad3/Chl1-like.
DR InterPro; IPR042493; XPD_DNA_FeS.
DR NCBIfam; TIGR00604; rad3; 1.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF34; REGULATOR OF TELOMERE ELONGATION HELICASE 1; 1.
DR Pfam; PF06733; DEAD_2; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00488; DEXDc2; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000030680}.
FT DOMAIN 5..321
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
SQ SEQUENCE 777 AA; 89081 MW; 4BB254148EF87FA1 CRC64;
MVAILGVEVA FPFQPYPVQR DYMEKVIQAL QTSQHAMLES PTGTGKTLCL LCSTLAWRQS
FIAKCQLSTI SKGQSSSLHH SDAEFFQGLE SSLSRAVGKE NQRALENDDG ATLDDLFQSL
GGNQGIQPTP RIIYTSRTHS QLAQAIDQLR KTIYRPSVIV LGSREQLCIH PQVSHLRGSE
QNRLCRSLCE SKGCKYRNNL KNFYKYEKMA DEILDLEDWV NFGKKEEICP YYLAKEREPT
SELIFLPYNY LVDLHLRESL RMDFSNDIIL FDEAHHIEDI AANCASFELT TSLLDACIHQ
LQRVKSKGDN LSSIQQYSQD AVSLLLALFR TLLNDMHHLL DGVSAHELVY EPSFLFQLLS
KVNLTPKTFD AFSSKIEQLF GDQHSDFESS VDFQSSSNDA VFTFLKYMRL LFKLSEEEAR
LSYVVCIYGE QKTEETRRRI TLSYWCFNPG VVMKQLVKGV RCLVLTSGTL SPLSFLESEL
QIPFPIQLEN RHIISQHQLF VGMLGLGPSG EVLNSSYRNR SLISYKRELG RCIYNFSLVI
PGGMLVFFPS YQLLMDCVEY WKTYSMQTSD QSKDFVSIWD SIYRRKSLVV ESKEEKEFQE
SFRHYQEQVD SRASGCILFG VCRGRMSEGI DFSDEYARAV ILVGIPFPPL QQRKVKMKQH
YLSTVKKNNP QRWYRLEALR AMNQAIGRVI RHEKDFGAII LCDERFPSMV HELSLWVQPF
VKNGCYSFGA LQSELIRFFK NQGRPSLKDQ KVTTPQLKTP QLAAGDEDHL FQVVGNK
//
