ID M2X3E5_GALSU Unreviewed; 709 AA.
AC M2X3E5;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=VASt domain-containing protein {ECO:0000259|PROSITE:PS51778};
GN ORFNames=Gasu_16840 {ECO:0000313|EMBL:EME30915.1};
OS Galdieria sulphuraria (Red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Galdieriales; Galdieriaceae;
OC Galdieria.
OX NCBI_TaxID=130081 {ECO:0000313|EMBL:EME30915.1, ECO:0000313|Proteomes:UP000030680};
RN [1] {ECO:0000313|Proteomes:UP000030680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=074W {ECO:0000313|Proteomes:UP000030680};
RX PubMed=23471408; DOI=10.1126/science.1231707;
RA Schonknecht G., Chen W.H., Ternes C.M., Barbier G.G., Shrestha R.P.,
RA Stanke M., Brautigam A., Baker B.J., Banfield J.F., Garavito R.M., Carr K.,
RA Wilkerson C., Rensing S.A., Gagneul D., Dickenson N.E., Oesterhelt C.,
RA Lercher M.J., Weber A.P.;
RT "Gene transfer from bacteria and archaea facilitated evolution of an
RT extremophilic eukaryote.";
RL Science 339:1207-1210(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB454495; EME30915.1; -; Genomic_DNA.
DR RefSeq; XP_005707435.1; XM_005707378.1.
DR AlphaFoldDB; M2X3E5; -.
DR EnsemblPlants; EME30915; EME30915; Gasu_16840.
DR GeneID; 17089608; -.
DR Gramene; EME30915; EME30915; Gasu_16840.
DR KEGG; gsl:Gasu_16840; -.
DR eggNOG; KOG1032; Eukaryota.
DR OrthoDB; 45896at2759; -.
DR Proteomes; UP000030680; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd13220; PH-GRAM_GRAMDC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR031968; VASt.
DR PANTHER; PTHR23319:SF4; AT22714P-RELATED; 1.
DR PANTHER; PTHR23319; UNCHARACTERIZED; 1.
DR Pfam; PF02893; GRAM; 1.
DR Pfam; PF16016; VASt; 1.
DR SMART; SM00568; GRAM; 1.
DR PROSITE; PS51778; VAST; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030680};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 606..628
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 354..537
FT /note="VASt"
FT /evidence="ECO:0000259|PROSITE:PS51778"
FT REGION 1..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..104
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 709 AA; 80288 MW; 962E74A84FD3ACC9 CRC64;
MSTENVDNHR VAMEVASSSQ RTLNTSATLE QRTSAVSFSH TQNNTSIGKS TTETQQDLSP
LASENTAVRT TPKTKERSWN NIVSKNTAQS DSASTNNNKS SKERNRVVTS NKLDKNGSSV
TNSSGLSDST LYSASQISHS KTLHKRFHLP DSENLLGEFA CALGKGVLMQ GKLYMTNSYL
CFFSGLFGRP LRVVIPLNDI SSIRKKNVAM IFPTAIQVVL KDGKKYFFAS FLARNLAFQR
LYLLWTLFKQ GKLAELKSSA QFDKILETFS NQEEDNEDMR TADDSVVSNS EDSEVHVEEN
QETDEQQRNK IAETLRMFEK GDFTQTSMFD SSFTDQDHLL VSYHLSTSVL HLGELIALNS
CPVGNETGEL NSLPSEEAGL NTTHNVLEEY HELRGDSNLE ISKWQRHSTL GCIRTIKYYS
PVHNKALAVG ISKTRNEEYQ RICLNPDKDF LLVEWTNQLL DIPFGDTFVM QTRMEAHDKS
THKSNNKPGC EVNIYLNVEW KKKVMWRRMI ESNIHRETVE SYETLIKVLK KHIENVRGSY
MMDEMVNNGN AKSIAKAKLE VQTDLTENSQ KNKSSSSQSS SLEEGLQSAN RKGSWNARLR
SLETQLYALF VFVLLISLVV LIGFFLVLRS QRTQGHVLSE RITQLEFLLE TQLDTKHRKE
WIPVAEYGNE ASVMKEQDLQ RLDSLVTQLN EVVSSLYSQH LLSKGKKES
//
