ID M2XQN9_GALSU Unreviewed; 244 AA.
AC M2XQN9;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Peroxidase {ECO:0000313|EMBL:EME25938.1};
DE EC=1.11.1.7 {ECO:0000313|EMBL:EME25938.1};
DE Flags: Fragment;
GN ORFNames=Gasu_64070 {ECO:0000313|EMBL:EME25938.1};
OS Galdieria sulphuraria (Red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Galdieriales; Galdieriaceae;
OC Galdieria.
OX NCBI_TaxID=130081 {ECO:0000313|EMBL:EME25938.1, ECO:0000313|Proteomes:UP000030680};
RN [1] {ECO:0000313|Proteomes:UP000030680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=074W {ECO:0000313|Proteomes:UP000030680};
RX PubMed=23471408; DOI=10.1126/science.1231707;
RA Schonknecht G., Chen W.H., Ternes C.M., Barbier G.G., Shrestha R.P.,
RA Stanke M., Brautigam A., Baker B.J., Banfield J.F., Garavito R.M., Carr K.,
RA Wilkerson C., Rensing S.A., Gagneul D., Dickenson N.E., Oesterhelt C.,
RA Lercher M.J., Weber A.P.;
RT "Gene transfer from bacteria and archaea facilitated evolution of an
RT extremophilic eukaryote.";
RL Science 339:1207-1210(2013).
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|PIRSR:PIRSR601621-2};
CC Note=Binds 2 calcium ions per subunit. {ECO:0000256|PIRSR:PIRSR601621-
CC 2};
CC -!- COFACTOR:
CC Name=heme b; Xref=ChEBI:CHEBI:60344;
CC Evidence={ECO:0000256|PIRSR:PIRSR601621-2};
CC Note=Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
CC {ECO:0000256|PIRSR:PIRSR601621-2};
CC -!- SIMILARITY: Belongs to the peroxidase family. Ligninase subfamily.
CC {ECO:0000256|ARBA:ARBA00006089}.
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DR EMBL; KB454708; EME25938.1; -; Genomic_DNA.
DR RefSeq; XP_005702458.1; XM_005702401.1.
DR AlphaFoldDB; M2XQN9; -.
DR STRING; 130081.M2XQN9; -.
DR EnsemblPlants; EME25938; EME25938; Gasu_64070.
DR GeneID; 17084928; -.
DR Gramene; EME25938; EME25938; Gasu_64070.
DR KEGG; gsl:Gasu_64070; -.
DR OrthoDB; 168803at2759; -.
DR Proteomes; UP000030680; Unassembled WGS sequence.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0140825; F:lactoperoxidase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0034599; P:cellular response to oxidative stress; IEA:InterPro.
DR Gene3D; 1.10.520.10; -; 1.
DR Gene3D; 1.10.420.10; Peroxidase, domain 2; 1.
DR InterPro; IPR044831; Ccp1-like.
DR InterPro; IPR002016; Haem_peroxidase.
DR InterPro; IPR010255; Haem_peroxidase_sf.
DR InterPro; IPR001621; Ligninase.
DR InterPro; IPR019793; Peroxidases_heam-ligand_BS.
DR PANTHER; PTHR31356:SF66; HEME-BINDING PEROXIDASE-RELATED; 1.
DR PANTHER; PTHR31356; THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF00141; peroxidase; 1.
DR PRINTS; PR00462; LIGNINASE.
DR PRINTS; PR00458; PEROXIDASE.
DR SUPFAM; SSF48113; Heme-dependent peroxidases; 1.
DR PROSITE; PS00435; PEROXIDASE_1; 1.
DR PROSITE; PS50873; PEROXIDASE_4; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|PIRSR:PIRSR601621-2};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Heme {ECO:0000256|PIRSR:PIRSR601621-2};
KW Iron {ECO:0000256|PIRSR:PIRSR601621-2};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR601621-2};
KW Oxidoreductase {ECO:0000313|EMBL:EME25938.1};
KW Peroxidase {ECO:0000313|EMBL:EME25938.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000030680}.
FT DOMAIN 1..142
FT /note="Plant heme peroxidase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50873"
FT REGION 155..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 204..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 71
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR601621-2"
FT BINDING 72
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR601621-2"
FT NON_TER 244
FT /evidence="ECO:0000313|EMBL:EME25938.1"
SQ SEQUENCE 244 AA; 25399 MW; EE5B30B709C2E761 CRC64;
SIADLINSCA VTALKFLNGP DVPVYYGRLD RNVPDPTGLI PEPTMSLSAL INAFSAIGFS
KEDVVTLSGA HSVGVCHGIP MCPGHNTSFG NHYYQELIEG DLSGKLPTDV ELLEDNTMRS
LVQQYANDNS QFFSDFSRVF GKYISRIHCN QTSTGPCPLD DIGNSTTSTS TSSVTSSVIP
VVASPSSSFP SSSSPIIIGS PIVISSSSSS SSSTSSSESF PPVPPISGPF SNPPSNPGGS
VLSV
//
