ID M2XSZ4_GALSU Unreviewed; 521 AA.
AC M2XSZ4;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=MFS transporter, SP family, sugar:H+ symporter {ECO:0000313|EMBL:EME26549.1};
GN ORFNames=Gasu_57830 {ECO:0000313|EMBL:EME26549.1};
OS Galdieria sulphuraria (Red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Galdieriales; Galdieriaceae;
OC Galdieria.
OX NCBI_TaxID=130081 {ECO:0000313|EMBL:EME26549.1, ECO:0000313|Proteomes:UP000030680};
RN [1] {ECO:0000313|Proteomes:UP000030680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=074W {ECO:0000313|Proteomes:UP000030680};
RX PubMed=23471408; DOI=10.1126/science.1231707;
RA Schonknecht G., Chen W.H., Ternes C.M., Barbier G.G., Shrestha R.P.,
RA Stanke M., Brautigam A., Baker B.J., Banfield J.F., Garavito R.M., Carr K.,
RA Wilkerson C., Rensing S.A., Gagneul D., Dickenson N.E., Oesterhelt C.,
RA Lercher M.J., Weber A.P.;
RT "Gene transfer from bacteria and archaea facilitated evolution of an
RT extremophilic eukaryote.";
RL Science 339:1207-1210(2013).
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000256|RuleBase:RU003346}.
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DR EMBL; KB454546; EME26549.1; -; Genomic_DNA.
DR RefSeq; XP_005703069.1; XM_005703012.1.
DR AlphaFoldDB; M2XSZ4; -.
DR EnsemblPlants; EME26549; EME26549; Gasu_57830.
DR GeneID; 17085516; -.
DR Gramene; EME26549; EME26549; Gasu_57830.
DR KEGG; gsl:Gasu_57830; -.
DR eggNOG; KOG0254; Eukaryota.
DR OMA; WMDYGTS; -.
DR OrthoDB; 1029916at2759; -.
DR Proteomes; UP000030680; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR NCBIfam; TIGR00879; SP; 1.
DR PANTHER; PTHR48020:SF9; MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48020; PROTON MYO-INOSITOL COTRANSPORTER; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030680};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU003346}.
FT TRANSMEM 37..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 417..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 42..473
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 521 AA; 58219 MW; F02F19903FC98655 CRC64;
MTFQMKSLMM KLGRLELQLK ETKVSFFNSI TLGNPKVFTW VLVAFASMGG LLSGLDQSLI
SGANLYMLAD LHLDSGQVSL VDSLMPLGAV LGALILSPTN EALGRKLSII VACLLYTLGA
GLEAGAHSVG MMYAGRFILG MGLGLEGGTV PVYVAECVAK KFRGNLVSLY QFNIALGEVF
GYVVAAIFVN VSGTWRWMLG SSLLFSTVLL VGMIFMPESP RYLMHKGREV ESYSVWKRIR
GVSDIDARRE FIVMRHLVEQ EQEEKKRLRY PYLDFIRVPR CRRAIVYANI MVFLGQFTGV
NAIMYYMSVL MSEVGFSSKQ SVFMSLVGGG SLLLGTIPAI LWMDRFGRRV AAITLLPGFF
VGLLIIGFGY FIPLSNVHSA EGVYLTGLII YMWFFGSYAC LTWVLPSEVY PTYLRSYGMT
SSDATLFLSA FIVTYNFSRM QNAMTKTGLA VGFYGGIAVF GWIYQVLYMP ETKNKTLEEI
DLVFSKPTKE LVRENWQSTK ETVSDLFHLR WKRAFGLQGE Y
//
